Search Results - "Surzhikov, S. A."

A Comparative Behavior Analysis of Cy5-Pyrimidine Nucleotides in Rolling Circle Amplification by Lapa, S. A., Chirkova, P. A., Surzhikov, S. A., Kuznetsova, V. E., Shershov, V. E., Chudinov, A. V.

“…Objective: The introduction of fluorescently labeled nucleotides in the process of DNA amplification in molecular genetic analysis is a very attractive…”
Get full text

Recombinase Polymerase Amplification for Rapid Detection of Human Bacterial Pneumonia Pathogens by Lapa, S. A., Surzhikov, S. A., Blagodatskikh, S. A., Shershov, V. E., Chudinov, A. V.

“…A diagnostic system based on recombinase polymerase amplification (RPA) has been developed to identify six bacterial pathogens of human pneumonia…”
Get full text

Detection of the IDH1/2 Gene Mutations in Tumor Samples with Low-Abundance Mutant Allele by Varachev, V. O., Guskov, D. A., Susova, O. Yu, Shekhtman, A. P., Rogozhin, D. V., Surzhikov, S. A., Chudinov, A. V., Zasedatelev, A. S., Nasedkina, T. V.

“…Objective: Identification of driver mutations in tumors is an extremely important task in oncology for the choice of treatment strategy and assessment of…”
Get full text

Cytotoxicity Studies of 5-Arylaminouracil Derivatives by Kezin, V. A., Matyugina, E. S., Surzhikov, S. A., Novikov, M. S., Maslova, A. A., Karpenko, I. L., Ivanov, A. V., Kochetkov, S. N., Khandazhinskaya, A. L.

“…We have previously shown that 5-arylaminouracil derivatives can inhibit HIV-1, herpesviruses, mycobacteria, and other pathogens through various mechanisms. The…”
Get full text

Preparation of recombinant serpins B3 and B4 and investigation of their specific interactions with antibodies using hydrogel-based microarrays by Butvilovskaya, V. I., Tsybulskaya, M. V., Tikhonov, A. A., Talibov, V. O., Belousov, P. V., Sazykin, A. Yu, Schwartz, A. M., Surzhikov, S. A., Stomakhin, A. A., Solopova, O. N., Rubina, A. Yu

“…The objective of this work was to obtain preparations of recombinant squamous-cell carcinoma antigens (serpins B3 and B4) and to investigate their interactions…”
Get full text

Infrared fluorescent markers for microarray DNA analysis by Spitsyn, M. A., Shershov, V. E., Kuznetsova, V. E., Barsky, V. E., Egorov, E. E., Emelyanova, M. A., Kreindlin, E. Ya, Lysov, Yu. P., Guseinov, T. O., Fesenko, D. E., Lapa, S. A., Surzhikov, S. A., Abramov, I. S., Nasedkina, T. V., Zasedatelev, A. S., Chudinov, A. V.

“…In order to expand the informational capabilities of molecular genetic research, new indotricarbocyanine dyes that fluoresce in the near infrared (IR) spectral…”
Get full text

Analysis of the genetic determinants of multidrug and extensive drug resistance in Mycobacterium tuberculosis with the use of an oligonucleotide microchip by Zimenkov, D. V., Kulagina, E. V., Antonova, O. V., Surzhikov, S. A., Bespyatykh, Yu. A., Shitikov, E. A., Ilina, E. N., Mikhailovich, V. M., Zasedatelev, A. S., Gryadunov, D. A.

“…Steadily growing resistance of the tuberculosis causative agent towards a broad spectrum of antituberculosis drugs calls for rapid and reliable methods for…”
Get full text

Effect of Spacers on DNA Probe Properties in Hybridization Analysis by Miftakhov, R. A., Lapa, S. A., Kuznetsova, V. E., Zolotov, A. M., Vasiliskov, V. A., Shershov, V. E., Surzhikov, S. A., Zasedatelev, A. S., Chudinov, A. V.

“…— A method of immobilizing oligonucleotides on the surface of a polyethylene terephthalate (PET) substrate has been developed. The effectiveness of the…”
Get full text

Association of NAT2 polymorphisms with susceptibility to psoriasis in the Moscow population by Kozhekbaeva, Zh. M, Gra, O. A, Fadeev, V. S, Goldenkova-Pavlova, I. V, Korsunskaya, I. M, Bruskin, S. A, Agafonova, E. E, Piruzyan, An. L, Surzhikov, S. A, Nasedkina, T. V

“…N-acetyltransferase 2 (NAT2) is a key enzyme of biotransformation phase II that metabolizes genotoxic compounds such as carcinogens and mutagens in different…”
Get full text

Slippage of the Primer Strand in the Primer Extension Reaction with Modified 2'-Deoxyuridine Triphosphates by Vasiliskov, V. A., Shershov, V. E., Miftahov, R. A., Kuznetsova, V. E., Radko, S. P., Lisitsa, A. V., Lapa, S. A., Surzhikov, S. A., Timofeev, E. N., Zasedatelev, A. S., Chudinov, A. V.

“…An effect of primer strand slippage was observed in the primer extension reaction due to replacement of thymidine triphosphate for modified analogs of dUTP…”
Get full text

Sequence specificity of protein-oligonucleotide interactions and protein isolation on sorptive media containing immobilized protein specific oligonucleotides by Rubina, A. Yu, Tsybulskaya, M. V., Zasedateleva, O. A., Popletaeva, S. B., Filippova, M. A., Butvilovskaya, V. I., Surzhikov, S. A., Stomakhin, A. A., Zasedatelev, A. S.

“…The sequence specificity of protein—oligonucleotide interactions based on the example of binase interaction with oligodeoxyribonucleotides immobilized in…”
Get full text

Fabrication of microarray of gel-immobilized compounds on a chip by copolymerization by Vasiliskov, A V, Timofeev, E N, Surzhikov, S A, Drobyshev, A L, Shick, V V, Mirzabekov, A D

“…The manufacturing of microchips containing oligonucleotides and proteins immobilized within gel pads, ranging in size from 10 x 10 to 100 x 100 microns, is…”
Get full text

Association of polymorphisms of xenobiotic-metabolizing genes with glucocorticoid-induced osteoporosis in patients with bronchial asthma by Gra, O. A., Moskalenko, M. V., Filimonova, N. A., Baranova, I. A., Glotov, A. S., Surzhikov, S. A., Koroleva, O. V., Goldenkova-Pavlova, I. V., Nasedkina, T. V.

“…Investigation of risk factors for glucocorticoid-induced (GI) osteoporosis, which is one of the most frequent and serious complications of long-term systemic…”
Get full text

Multiplex Assay to Evaluate the Genetic Risk of Developing Human Melanoma by Fesenko, D. O., Abramov, I. S., Shershov, V. E., Kuznetsova, V. E., Surzhikov, S. A., Grechishnikova, I. V., Barsky, V. E., Chudinov, A. V., Nasedkina, T. V.

“…A genotyping procedure based on single-step PCR and subsequent allele-specific hybridization on a hydrogel biochip was developed to address the polymorphisms…”
Get full text

Novel 5-Alkylcarboxamide-2'-Deoxyuridine-5'-Triphosphates for Enzymatic Synthesis of Highly Modified DNA by Vasiliskov, V. A., Lapa, S. A., Kuznetsova, V. E., Surzhikov, S. A., Shershov, V. E., Spitsyn, M. A., Guseinov, T. O., Miftahov, R. A., Zasedateleva, O. A., Lisitsa, A. V., Radko, S. P., Zasedatelev, A. S., Timofeev, E. N., Chudinov, A. V.

“…The synthesis of deoxyuridine triphosphate derivatives with alkyl groups of various chain length attached to the pyrimidine base by the trans -alkene linker…”
Get full text

Multiplex Genotyping of Allelic Variants of Genes Involved in Metabolizing Antileukemic Drugs by Fesenko, D. O., Avdonina, M. A., Gukasyan, L. G., Surzhikov, S. A., Chudinov, A. V., Zasedatelev, A. S., Nasedkina, T. V.

“…A biochip, primer set, and genotyping protocol were developed to simultaneously address 16 single nucleotide polymorphisms in antileukemic drug metabolism…”
Get full text

The Effect of the Chromophore Charge on the Efficiency of Incorporation of Fluorescently-labeled Nucleotides in Matrix Synthesis by Taq DNA Polymerase by Shershov, V E, Kuznetsova, V E, Lysov, Yu P, Guseinov, T O, Barsky, V E, Spitsyn, M A, Zasedateleva, O A, Vasiliskov, V A, Surzhikov, S A, Zasedatelev, A S, Chudinov, A V

“…In order to study the effect of an electrical charge of the chromophore, on the efficiency of incorporation of fluorescently-labeled nucleotides into DNA…”
Get more information

Development of a Biochip for Analyzing Polymorphism of the Biotransformation Genes by Glotov, A S, Nasedkina, T V, Ivaschenko, TE, Urasov, R A, Surzhikov, SA, Pan'kov, S V, Chudinov, A V, Baranov, V S, Zasedatelev, A S

“…Large-scale population studies, diagnosis of genetic predisposition to a broad range of multifactorial diseases, and screening of polymorphic loci associated…”
Get full text

Preparation of recombinant serpins B3 and B4 and investigation of their specific interactions with antibodies using hydrogel-based microarrays by Butvilovskaya, V I, Tsybulskaya, M V, Tikhonov, A A, Talibov, V O, Belousov, P V, Sazykin, A Yu, Schwartz, A M, Putlyaeva, L V, Surzhikov, S A, Stomakhin, A A, Solopova, O N, Rubina, A Yu

“…The objective of this work was to obtain preparations of recombinant squamous-cell carcinoma antigens (serpins B3 and B4) and to investigate their interactions…”
Get more information

A new immuno-PCR format for serological diagnosis of colon cancer by Nikitina, I. G., Sabirova, E. Yu, Solopova, O. N., Surzhikov, S. A., Grineva, E. N., Karpov, V. L., Lisitsyn, N. A., Beresten, S. F.

“…A new immuno-PCR format based on the detection of CDH17 membrane protein in serum exosomes is proposed. Using the technique described, it was possible to…”
Get full text