Search Results - "Surugiu, Roxana"

Dietary habits, lifestyle factors and neurodegenerative diseases by Popa-Wagner, Aurel, Dumitrascu, Dinu, Capitanescu, Bogdan, Petcu, Eugen, Surugiu, Roxana, Fang, Wen-Hui, Dumbrava, Danut-Adrian

“…Worldwide stroke is increasing in parallel with modernization, changes in lifestyle, and the growing elderly population. Our review is focused on the link…”
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Mesenchymal stromal cell-derived small extracellular vesicles promote neurological recovery and brain remodeling after distal middle cerebral artery occlusion in aged rats by Dumbrava, Danut-Adrian, Surugiu, Roxana, Börger, Verena, Ruscu, Mihai, Tertel, Tobias, Giebel, Bernd, Hermann, Dirk M., Popa-Wagner, Aurel

“…Small extracellular vesicles (sEVs) obtained from mesenchymal stromal cells (MSCs) promote neurological recovery after middle cerebral artery occlusion (MCAO)…”
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Oxidative Stress and Antioxidant Defense Mechanisms in Acute Ischemic Stroke Patients with Concurrent COVID-19 Infection by Pinoșanu, Elena Anca, Surugiu, Roxana, Burada, Emilia, Pîrșcoveanu, Denisa, Stănciulescu, Camelia Elena, Sandu, Raluca Elena, Pisoschi, Cătălina, Albu, Carmen Valeria

“…Stroke remains a debilitating cerebrovascular condition associated with oxidative stress, while COVID-19 has emerged as a global health crisis with…”
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Molecular Mechanisms of Healthy Aging: The Role of Caloric Restriction, Intermittent Fasting, Mediterranean Diet, and Ketogenic Diet-A Scoping Review by Surugiu, Roxana, Iancu, Mihaela Adela, Vintilescu, Ștefănița Bianca, Stepan, Mioara Desdemona, Burdusel, Daiana, Genunche-Dumitrescu, Amelia Valentina, Dogaru, Carmen-Adriana, Dumitra, Gheorghe Gindrovel

“…As the population ages, promoting healthy aging through targeted interventions becomes increasingly crucial. Growing evidence suggests that dietary…”
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Intracortical Administration of the Complement C3 Receptor Antagonist Trifluoroacetate Modulates Microglia Reaction after Brain Injury by Popa-Wagner, Aurel, Olaru, Denisa Greta, Gresita, Andrei, Dumbrava, Danut, Catalin, Bogdan, Surugiu, Roxana, Hermann, Dirk M.

“…Worldwide, millions of individuals suffer an ischemic stroke each year, causing major disability, especially in the elderly, where stroke is the number one…”
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Rhoa/ROCK, mTOR and Secretome-Based Treatments for Ischemic Stroke: New Perspectives by Pinoșanu, Elena Anca, Pîrșcoveanu, Denisa, Albu, Carmen Valeria, Burada, Emilia, Pîrvu, Andrei, Surugiu, Roxana, Sandu, Raluca Elena, Serb, Alina Florina

“…Ischemic stroke triggers a complex cascade of cellular and molecular events leading to neuronal damage and tissue injury. This review explores the potential…”
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Cellular and Molecular Mechanisms Underlying Non-Pharmaceutical Ischemic Stroke Therapy in Aged Subjects by Sandu, Raluca Elena, Dumbrava, Danut, Surugiu, Roxana, Glavan, Daniela-Gabriela, Gresita, Andrei, Petcu, Eugen Bogdan

“…The incidence of ischemic stroke in humans increases exponentially above 70 years both in men and women. Comorbidities like diabetes, arterial hypertension or…”
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Present Status and Future Challenges of New Therapeutic Targets in Preclinical Models of Stroke in Aged Animals with/without Comorbidities by Popa-Wagner, Aurel, Glavan, Daniela-Gabriela, Olaru, Andrei, Olaru, Denissa-Greta, Margaritescu, Otilia, Tica, Oana, Surugiu, Roxana, Sandu, Raluca Elena

“…The aging process, comorbidities, and age-associated diseases are closely dependent on each other. Cerebral ischemia impacts a wide range of systems in an…”
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Vasculature Remodeling in a Rat Model of Cerebral Ischemia. The Fate of the BrdU-Labeled Cells Prior to Stroke by Surugiu, Roxana, Glavan, Daniela, Popescu, Mircea, Margaritescu, Otilia, Eugen, Radu, Popa-Wagner, Aurel

“…Despite the clinical significance of post-stroke angiogenesis, a detailed phenotypic analysis of pre-stroke vascular remodeling and post-stroke angiogenesis…”
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Genetic plasma biomarkers associated with ischemic stroke by Mihai Andrei Ruscu, Daiana Burdusel, Andreea-Mihaela Cercel, Madalina Aldea, Dirk M. Hermann, Israel Fernandez Cadenas, Thorsten R. Doeppner, Roxana Surugiu, Aurel Popa-Wagner

“…Aim: Stroke is one of the leading causes of death and disability worldwide. Plasma biomarkers have long been used to evaluate physiological or pathological…”
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Pharmacological and stem cell therapy of stroke in animal models: Do they accurately reflect the response of humans? by Ruscu, Mihai, Glavan, Daniela, Surugiu, Roxana, Doeppner, Thorsten R., Hermann, Dirk M., Gresita, Andrei, Capitanescu, Bogdan, Popa-Wagner, Aurel

“…Cerebrovascular diseases are the second leading cause of death worldwide. Despite significant research investment, the only available therapeutic options are…”
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Recent Advances in Mono- and Combined Stem Cell Therapies of Stroke in Animal Models and Humans by Surugiu, Roxana, Olaru, Andrei, Hermann, Dirk M, Glavan, Daniela, Catalin, Bogdan, Popa-Wagner, Aurel

“…Following the failure of acute neuroprotection therapies, major efforts are currently made worldwide to promote neurological recovery and brain plasticity in…”
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Clinical Ageing by Surugiu, Roxana, Burdusel, Daiana, Ruscu, Mihai-Andrei, Cercel, Andreea, Hermann, Dirk M, Cadenas, Israel Fernandez, Popa-Wagner, Aurel

“…Ageing is generally characterised by the declining ability to respond to stress, increasing homeostatic imbalance, and increased risk of ageing-associated…”
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Grafts of hydrogel-embedded electrically stimulated subventricular stem cells into the stroke cavity improves functional recovery of mice by Cercel, Andreea-Mihaela, Boboc, Ianis KS, Surugiu, Roxana, Doeppner, Thorsten R., Hermann, Dirk M., Catalin, Bogdan, Gresita, Andrei, Popa-Wagner, Aurel

“…The major aim of stroke therapy is to stimulate brain repair and improve behavioral recovery after cerebral ischemia. One option is to stimulate endogenous…”
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Extracellular Vesicles Obtained from Hypoxic Mesenchymal Stromal Cells Induce Neurological Recovery, Anti-inflammation, and Brain Remodeling After Distal Middle Cerebral Artery Occlusion in Rats by Abuzan, Mihaela, Surugiu, Roxana, Wang, Chen, Mohamud-Yusuf, Ayan, Tertel, Tobias, Catalin, Bogdan, Doeppner, Thorsten R, Giebel, Bernd, Hermann, Dirk M, Popa-Wagner, Aurel

“…Small extracellular vesicles (sEVs) obtained from mesenchymal stromal cells (MSCs) have shown considerable promise as restorative stroke treatment. In a…”
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Predictive Value of Pulmonary Involvement in Stroke Patients Co-Infected with COVID-19 by Pinosanu, Elena Anca, Burada, Emilia, Pirscoveanu, Denisa, Aldea, Madalina, Albu, Carmen Valeria, Surugiu, Roxana, Sandu, Raluca Elena

“…In response to the intricate clinical challenges posed by the intersection of COVID-19 and acute ischemic stroke, the Neuropsychiatry Hospital of Craiova,…”
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Nephrotic syndrome as a possible indicator of colonic cancer: A case report by Surugiu, Roxana, Vintilescu, Ștefănița Bianca, Sandu, Raluca Elena, Pirscoveanu, Denisa, Pirici, Daniel, Neagoe, Carmen Daniela, Matei, Daniela, Aldea, Mădălina, Dumitra, Gheorghe Gindrovel, Stepan, Mioara Desdemona, Genunche-Dumitrescu, Amelia Valentina

“…The concept of paraneoplastic syndromes encompasses a spectrum of indirect clinical manifestations caused by secretion of bioactive products by malignant…”
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CELLULAR AUTOPHAGY – TREATMENT TARGET FOR THE AGING PROCESS by Popa-Wagner, Aurel, Filfan (Aldea), Madalina, Zavaleanu, Alexandra, Surugiu, Roxana, Gresita, Andrei, Dumbrava, Danut

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Molecular mechanisms underlying neurodevelopmental disorders, ADHD and autism by Bădescu, George Mihai, Fîlfan, Mădălina, Sandu, Raluca Elena, Surugiu, Roxana, Ciobanu, Ovidiu, Popa-Wagner, Aurel

“…Neurodevelopmental disorders such as attention deficit hyperactivity disorder and autism represent a significant economic burden, which justify vigorous…”
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