Search Results - "Surles, J R"

Binding and metabolism of platelet-activating factor by human neutrophils by O'FLAHERTY, J. T, SURLES, J. R, REDMAN, J, JACOBSON, D, PIANTADOSI, C, WYKLE, R. L

“…Human polymorphonuclear neutrophils rapidly incorporated radiolabeled platelet-activating factor, 1-O-[hexadecyl-9,…”
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Desorption chemical ionization mass spectrometry of 1-O-alkyl-2-O-acetyl-sn-glycero-3-phosphocholines and analogues by Thomas, M J, Samuel, M, Wykle, R L, Surles, J R, Piantadosi, C

“…Ammonia desorption chemical ionization of ether-linked phospholipids of the type 1-O-alkyl-2-O-acetyl-sn-glycero-3-phosphocholine (platelet-activating factors)…”
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Synthesis and evaluation of novel ether lipid nucleoside conjugates for anti-HIV-1 activity by Piantadosi, Claude, Marasco, Canio J, Morris-Natschke, Susan L, Meyer, Karen L, Gumus, Fatma, Surles, Jefferson R, Ishaq, Khalid S, Kucera, Louis S, Iyer, Nathan

“…Combinations of an amidoalkylphosphocholine, 8, and AZT have been found to cause an apparent synergistic action in suppressing infectious HIV-1 replication. In…”
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Multigram synthesis of 1‐alkylamido phospholipids by Surles, Jefferson R., Morris‐Natschke, Susan, Marx, Michael H., Piantadosi, Claude

“…Phospholipids containing a 1‐alkylamido linkage have shown promisingin vitro neoplastic cell growth inhibitory properties and anti‐human immunodeficiency viral…”
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Synthesis of sulfur analogs of alkyl lysophospholipid and neoplastic cell growth inhibitory properties by Morris-Natschke, Susan, Surles, Jefferson R, Daniel, Larry W, Berens, Michael E, Modest, Edward J, Piantadosi, Claude

“…Five sulfur-containing phospholipid analogues (compounds 1-5) of alkyl lysophospholipid (1-O-alkyl-2-O-methyl-rac-glycero-3-phosphocholine, ALP) were…”
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Facile synthesis of platelet-activating factor and racemic analogs containing unsaturation in the sn-1-alkyl chain by Surles, Jefferson R, Wykle, Robert L, O'Flaherty, Joseph T, Salzer, William L, Thomas, Michael J, Snyder, Fred, Piantadosi, Claude

“…Platelet-activating factor, 1 (PAF, 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine), and octadecyl-PAF were synthesized chemically as the racemates. The…”
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1-O-alkyl-2-N-methylcarbamyl-glycerophosphocholine: a biologically potent, non-metabolizable analog of platelet-activating factor by O'Flaherty, J T, Redman, Jr, J F, Schmitt, J D, Ellis, J M, Surles, J R, Marx, M H, Piantadosi, C, Wykle, R L

“…We prepared unlabeled and 3H-labeled analogs of platelet-activating factor (PAF) containing a N-methylcarbamyl residue at the sn-2 position. PAF and its…”
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Human neutrophils incorporate arachidonic acid and saturated fatty acids into separate molecular species of phospholipids by Swendsen, C L, Chilton, F H, O'Flaherty, J T, Surles, J R, Piantadosi, C, Waite, M, Wykle, R L

“…The incorporation of radiolabeled arachidonic acid and saturated fatty acids into choline-linked phosphoglycerides (PC) of rabbit and human neutrophils was…”
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Structural features of platelet activating factor (1-alkyl-2-acetyl-sn-glycero-3-phosphocholine) required for hypotensive and platelet serotonin responses by Blank, M L, Cress, E A, Lee, T C, Malone, B, Surles, J R, Piantadosi, C, Hajdu, J, Snyder, F

“…A number of analogs similar in structure to biologically active 1-alkyl-2-acetyl-sn-glycero-3-phosphocholine (platelet activating factor) were tested for their…”
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Platelet-activating factor and analogues: comparative studies with human neutrophils and rabbit platelets by O'Flaherty, J T, Salzer, W L, Cousart, S, McCall, C E, Piantadosi, C, Surles, J R, Hammett, M J, Wykle, R L

“…Platelet-activating factor and 12 structural analogues stimulated rabbit platelets to aggregate and release [14C]-serotonin. They likewise caused human…”
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Ether lipids inhibit the effects of phorbol diester tumor promoters by Daniel, Larry W., Etkin, Lori A., Morrison, Bennett T., Parker, Judy, Morris‐Natschke, Susan, Surles, Jefferson R., Plantadosi, Claude

“…Recent studies have shown that the tumor promoter 12‐O‐tetradecanoyl‐phorbol‐13‐acetate (TPA) stimulates protein kinase C (PKC), whereas the ether‐linked…”
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Stereospecific activity of 1-O-alkyl-2-O-acetyl-sn-glycero-3-phosphocholine and comparison of analogs in the degranulation of platelets and neutrophils by Wykle, R L, Miller, C H, Lewis, J C, Schmitt, J D, Smith, J A, Surles, J R, Piantadosi, C, O'Flaherty, J T

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Synthesis and evidence for the stability of a glycerophosphochloridate: rac-1-O-hexadecyl-2-O-(methylcarbamyl)-sn-glycero-3-phosphorochloridocholine by Surles, Jefferson R., Marx, Michael H., Piantadosi, Claude, Wykle, Robert L., Schmitt, Jeffrey D.

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Platelet activating factor (1- O-alkyl-2- O-acetyl- sn-glycero-3-phosphocholine) : Activity of analogs lacking oxygen at the 2-position by Wykle, Robert L., Surles, Jefferson R., Piantadosi, Claude, Salzer, William L., O'Flaherty, Joseph T.

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Halogenated biphenyl transport by blood components by Matthews, H B, Surles, J R, Carver, J G, Anderson, M W

“…Halogenated biphenyl transport by components of rat blood was studied under both in vivo and in vitro conditions. Fractionation of plasma components by gel…”
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