Search Results - "Suri, Nitasha"
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2-Anilinonicotinyl linked 2-aminobenzothiazoles and [1,2,4]triazolo[1,5-b] [1,2,4]benzothiadiazine conjugates as potential mitochondrial apoptotic inducers
Published in Bioorganic & medicinal chemistry (01-12-2011)“…A series of N-(2-anilino-pyridyl) linked 2-amino benzothiazoles (4a–n) and [1,2,4]triazolo [1,5-b]benzothiadiazine conjugates (5a–j) have been designed,…”
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2
Synthesis and cytotoxic evaluation of substituted 3-(3′-indolyl-/3′-pyridyl)-isoxazolidines and bis-indoles
Published in Acta pharmaceutica Sinica. B (01-02-2012)“…Regio- and stereoselective 1,3-dipolar cycloadditions of C-(3-indolyl)-N-phenylnitrone (10) were carried out with different mono-substituted, disubstituted and…”
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3
Cytotoxic evaluation of semisynthetic ester and amide derivatives of oleanolic acid
Published in Natural product communications (01-10-2010)“…Although a number of chemicals have been isolated from Lantana camara, only a few have been evaluated for their biological significance. As part of our drug…”
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Synthesis and anticancer activities of new Benzothiadiazinyl Hydrazinecarboxamides and Anilino[1,2,4]triazolo[1,5-b][1,2,4]thiadiazine 5,5-diones
Published in Medicinal chemistry (Shp-sariqah, United Arab Emirates) (01-05-2011)“…Two series of compounds (5-14 and 15-23) based on the scaffolds of…”
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5
Sphaeranthus indicus Induces Apoptosis Through Mitochondrial-Dependent Pathway in HL-60 Cells and Exerts Cytotoxic Potential on Several Human Cancer Cell Lines
Published in Integrative cancer therapies (01-05-2013)“…Purpose. The study was designed to screen Sphaeranthus indicus, Ganoderma lucidum, and Urtica dioica for their anticancer activity against human cancer cell…”
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Pharmacophore, QSAR, and ADME based semisynthesis and in vitro evaluation of ursolic acid analogs for anticancer activity
Published in Journal of molecular modeling (01-07-2012)“…In the present work, QSAR models for predicting the activities of ursolic acid analogs against human lung (A-549) and CNS (SF-295) cancer cell lines were…”
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Synthesis of a novel series of artemisinin dimers with potent anticancer activity involving Sonogashira cross-coupling reaction
Published in Bioorganic & medicinal chemistry letters (01-01-2014)“…A series of C-10 acetal artemisinin dimers were synthesized using Sonogashira cross-coupling reaction. All these novel semisynthetic artemisinin dimers…”
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8
Discovery of novel small molecule EGFR inhibitory leads by structure and ligand-based virtual screening
Published in Medicinal chemistry research (2017)“…In modern drug discovery, virtual screening is an attractive and cost-effective approach, which is widely applied to filter chemical compound libraries for the…”
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Synthesis of a novel series of highly functionalized Baylis–Hillman adducts of artemisinin with potent anticancer activity
Published in Tetrahedron letters (07-08-2013)“…A novel series of densely functionalized derivatives of artemisinin have been synthesized using Baylis–Hillman reaction and their further applicability has…”
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10
Synthesis and anti-cancer activity of some novel C-17 analogs of ursolic and oleanolic acids
Published in Medicinal chemistry research (01-03-2013)“…A series of seventeen novel analogs of ursolic and oleanolic acid were synthesized (60–98 %), and evaluated for their anti-cancer potential against a panel of…”
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11
Synthesis of a novel series of highly functionalized BaylisaHillman adducts of artemisinin with potent anticancer activity
Published in Tetrahedron letters (01-08-2013)“…A novel series of densely functionalized derivatives of artemisinin have been synthesized using BaylisaHillman reaction and their further applicability has…”
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12
Novel C-ring analogs of ursolic acid: synthesis and cytotoxic evaluation
Published in Natural product communications (01-12-2014)“…Ursolic acid (1), a natural pentacyclic triterpenic acid, afforded a variety of ring-C transformed products (5-11) when treated with N-bromosuccinimide under…”
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13
Synthesis and in vitro anticancer activity of brevifoliol derivatives substantiated by in silico approach
Published in Medicinal chemistry research (01-09-2014)“…Five novel derivatives 1a , 1b , 1c , 2 and 3 of brevifoliol were synthesized. The structures of all the synthesized derivatives were established on the basis…”
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Pharmacognostic standardisation and antiproliferative activity of aegle marmelos (L.) Correa leaves in various human cancer cell lines
Published in Indian journal of pharmaceutical sciences (01-11-2013)“…Therapeutic management of cancer is a great clinical challenge and alternative medicines are being extensively explored to have integrated approach to cure…”
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