Search Results - "Supper, Valentina"
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1
Spiny mice (Acomys) cells fail to engraft in NOD scid gamma
Published in PloS one (19-05-2023)“…Immune cells and stromal cells regulate wound healing and regeneration through complex activation patterns with spatiotemporal variation. The scarless…”
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2
Chemotherapy-induced reversal of ciltacabtagene autoleucel–associated movement and neurocognitive toxicity
Published in Blood (05-10-2023)“…In 2 complementary Letters to Blood, Karschnia et al and Graham et al provide new insights into the neurological toxicities that are observed with B-cell…”
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3
Chemical genetic control of cytokine signaling in CAR-T cells using lenalidomide-controlled membrane-bound degradable IL-7
Published in Leukemia (01-03-2024)“…CAR-T cell therapy has emerged as a breakthrough therapy for the treatment of relapsed and refractory hematologic malignancies. However, insufficient CAR-T…”
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4
Pharmacological Inhibition of Inositol Hexakisphosphate Kinase 1 Protects Mice against Obesity-Induced Bone Loss
Published in Biology (Basel, Switzerland) (24-08-2022)“…Obesity and type II diabetes mellitus (T2DM) are prominent risk factors for secondary osteoporosis due to the negative impacts of hyperglycemia and excessive…”
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5
Novel role for alpha-2-macroglobulin (A2M) as a disease modifying protein in senile osteoporosis
Published in Frontiers in cell and developmental biology (30-10-2023)“…In the rapidly aging U.S. population, age-induced bone loss (senile osteoporosis) represents a major public health concern that is associated with a…”
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6
310 Targeted delivery of a VEGF-blocking scFv to enhance CAR-T cell potency
Published in Journal for immunotherapy of cancer (01-11-2023)“…BackgroundBlockade of the vascular endothelial growth factor (VEGF) pathway represents a long-standing strategy for anti-tumor activity, with drugs employing…”
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7
Spiny mice
Published in PloS one (19-05-2023)“…Immune cells and stromal cells regulate wound healing and regeneration through complex activation patterns with spatiotemporal variation. The scarless…”
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Journal Article -
8
CD70 CAR T cells secreting an anti-CD33/anti-CD3 dual targeting antibody overcome antigen heterogeneity in AML
Published in Blood (21-11-2024)“…CD70 has emerged as a promising target in acute myeloid leukemia (AML), and we have previously demonstrated the potency of an optimized CD70-targeted…”
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