Search Results - "Suping, REN"

High-resolution crystal structure of a hepatitis B virus replication inhibitor bound to the viral core protein by Klumpp, Klaus, Lam, Angela M., Lukacs, Christine, Vogel, Robert, Ren, Suping, Espiritu, Christine, Baydo, Ruth, Atkins, Kateri, Abendroth, Jan, Liao, Guochun, Efimov, Andrey, Hartman, George, Flores, Osvaldo A.

“…The hepatitis B virus (HBV) core protein is essential for HBV replication and an important target for antiviral drug discovery. We report the first, to our…”
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Effects of silicon carbide MOSFETs on the efficiency and power quality of a microgrid-connected inverter by Ding, Xiaofeng, Chen, Feida, Du, Min, Guo, Hong, Ren, Suping

“…•The characteristics comparison between SiC-inverter and Si-inverter is implemented, considering thermal effects.•The voltage distortion of inverters is…”
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Overexpression of TIM-3 in Macrophages Aggravates Pathogenesis of Pulmonary Fibrosis in Mice by Wang, Yu, Kuai, Qiyuan, Gao, Fenghua, Wang, Yanbing, He, Min, Zhou, Hong, Han, Gencheng, Jiang, Xingwei, Ren, Suping, Yu, Qun

“…Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive lung disorder and lacks effective treatments because of unclear mechanisms. Aberrant function of…”
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Change of knowledge base and the driving mechanism of innovation cooperation in resource-based cities by Xiao, YAN, Suping, REN, Jianjun, TU

“…[Objective] This study aimed to explore the pattern of change of knowledge base in resource-based cities and analyze the driving effect of innovation…”
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Protracted rosiglitazone treatment exacerbates inflammation in white adipose tissues of adipocyte-specific Nfe2l1 knockout mice by Ren, Suping, Hou, Yongyong, Zuo, Zhuo, Liu, Zhiyuan, Wang, Huihui, Xu, Yuanyuan, Yamamoto, Masayuki, Zhang, Qiang, Fu, Jingqi, Pi, Jingbo

“…Nuclear factor-erythroid 2-related factor 1 (NFE2L1, also known as NRF1) belongs to the CNC-bZIP family and is a master regulator of cellular adaptive…”
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Evaluation of SARS-CoV-2 3C-like protease inhibitors using self-assembled monolayer desorption ionization mass spectrometry by Gurard-Levin, Zachary A., Liu, Cheng, Jekle, Andreas, Jaisinghani, Ruchika, Ren, Suping, Vandyck, Koen, Jochmans, Dirk, Leyssen, Pieter, Neyts, Johan, Blatt, Lawrence M., Beigelman, Leonid, Symons, Julian A., Raboisson, Pierre, Scholle, Michael D., Deval, Jerome

“…Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the cause of the COVID-19 pandemic that began in 2019. The coronavirus 3-chymotrypsin-like…”
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2-D Magnetic Properties Measurement System for Electrical Steel Sheets Considering Laminated Direction Mechanical Stress by Ding, Xiaofeng, Ren, Suping, Xiong, Yanwen, Chen, Feida, Xu, Jinquan

“…The 2-D rotating magnetic field is demonstrated in electrical steel sheets, which are widely used in iron cores of motors, etc. In addition, the magnetic…”
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Co-Delivery of Gemcitabine and Mcl-1 SiRNA via Cationic Liposome-Based System Enhances the Efficacy of Chemotherapy in Pancreatic Cancer by Wang, Yanbing, Gao, Fenghua, Jiang, Xingwei, Zhao, Xiao, Wang, Yu, Kuai, Qiyuan, Nie, Guangjun, He, Min, Pan, Yingjie, Shi, Wei, Ren, Suping, Yu, Qun

“…Myeloid cell leukemia 1 (Mcl-1) overexpression is found in various human tumors and has emerged as a promising new target for pancreatic cancer treatment…”
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The gene expression profiles of primary and metastatic melanoma yields a transition point of tumor progression and metastasis by Riker, Adam I, Enkemann, Steven A, Fodstad, Oystein, Liu, Suhu, Ren, Suping, Morris, Christopher, Xi, Yaguang, Howell, Paul, Metge, Brandon, Samant, Rajeev S, Shevde, Lalita A, Li, Wenbin, Eschrich, Steven, Daud, Adil, Ju, Jingfang, Matta, Jaime

“…The process of malignant transformation, progression and metastasis of melanoma is poorly understood. Gene expression profiling of human cancer has allowed for…”
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CL316243 treatment mitigates the inflammation in white adipose tissues of juvenile adipocyte-specific Nfe2l1 knockout mice by Wang, Zhendi, Hou, Yongyong, Ren, Suping, Liu, Zhiyuan, Zuo, Zhuo, Huang, Sicui, Wang, Wanqi, Wang, Huihui, Chen, Yanyan, Xu, Yuanyuan, Yamamoto, Masayuki, Zhang, Qiang, Fu, Jingqi, Pi, Jingbo

“…Nuclear factor-erythroid 2-related factor 1 (NFE2L1) is a key transcription factor that regulates cellular adaptive responses to various stresses. Our previous…”
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Nrf2 in adipocytes by Wang, Zhendi, Zuo, Zhuo, Li, Lu, Ren, Suping, Gao, Tianchang, Fu, Jingqi, Hou, Yongyong, Chen, Yanyan, Pi, Jingbo

“…White adipocytes play a key role in maintaining whole body energy homeostasis by forming white adipose tissue (WAT). The impairment of WAT formation or WAT…”
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Long isoforms of NRF1 negatively regulate adipogenesis via suppression of PPARγ expression by Xue, Peng, Hou, Yongyong, Zuo, Zhuo, Wang, Zhendi, Ren, Suping, Dong, Jian, Fu, Jingqi, Wang, Huihui, Andersen, Melvin E., Zhang, Qiang, Xu, Yuanyuan, Pi, Jingbo

“…Nuclear factor erythroid 2-related factor 1 (NRF1), a ubiquitously expressed CNC-bZIP transcription factor, plays a critical role in white adipocyte (WAC)…”
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Structure and Function of Flavivirus NS5 Methyltransferase by Zhou, Yangsheng, Ray, Debashish, Zhao, Yiwei, Dong, Hongping, Ren, Suping, Li, Zhong, Guo, Yi, Bernard, Kristen A, Shi, Pei-Yong, Li, Hongmin

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Chidamide Inhibits Aerobic Metabolism to Induce Pancreatic Cancer Cell Growth Arrest by Promoting Mcl-1 Degradation by He, Mu, Qiao, Zhixin, Wang, Yanbing, Kuai, Qiyuan, Li, Changlan, Wang, Yu, Jiang, Xingwei, Wang, Xuanlin, Li, Weijing, He, Min, Ren, Suping, Yu, Qun

“…Pancreatic cancer is a fatal malignancy worldwide and urgently requires valid therapies. Previous research showed that the HDAC inhibitor chidamide is a…”
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Tumor Regression upon Intratumoral and Subcutaneous Dosing of the STING Agonist ALG-031048 in Mouse Efficacy Models by Jekle, Andreas, Thatikonda, Santosh Kumar, Jaisinghani, Ruchika, Ren, Suping, Kinkade, April, Stevens, Sarah K, Stoycheva, Antitsa, Rajwanshi, Vivek K, Williams, Caroline, Deval, Jerome, Mukherjee, Sucheta, Zhang, Qingling, Chanda, Sushmita, Smith, David B, Blatt, Lawrence M, Symons, Julian A, Gonzalvez, Francois, Beigelman, Leonid

“…Stimulator of interferon genes (STING) agonists have shown potent anti-tumor efficacy in various mouse tumor models and have the potential to overcome…”
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Single-nucleus RNA-sequencing reveals NRF1/NFE2L1 as a key factor determining the thermogenesis and cellular heterogeneity and dynamics of brown adipose tissues in mice by Shen, Wei, Ren, Suping, Hou, Yongyong, Zuo, Zhuo, Liu, Shengnan, Liu, Zhiyuan, Fu, Jingqi, Wang, Huihui, Yang, Bei, Zhao, Rui, Chen, Yanyan, Yamamoto, Masayuki, Xu, Yuanyuan, Zhang, Qiang, Pi, Jingbo

“…Brown adipose tissue (BAT) is a major site of non-shivering thermogenesis in mammals and plays an important role in energy homeostasis. Nuclear…”
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The roles of NFE2L1 in adipocytes: Structural and mechanistic insight from cell and mouse models by Ren, Suping, Bian, Yiying, Hou, Yongyong, Wang, Zhendi, Zuo, Zhuo, Liu, Zhiyuan, Teng, Yue, Fu, Jingqi, Wang, Huihui, Xu, Yuanyuan, Zhang, Qiang, Chen, Yanyan, Pi, Jingbo

“…Adipocytes play pivotal roles in maintaining energy homeostasis by storing lipids in adipose tissue (AT), regulating the flux of lipids between AT and the…”
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CNC-bZIP protein NFE2L1 regulates osteoclast differentiation in antioxidant-dependent and independent manners by Liu, Zhiyuan, Wang, Huihui, Hou, Yongyong, Yang, Yang, Jia, Jingkun, Wu, Jinzhi, Zuo, Zhuo, Gao, Tianchang, Ren, Suping, Bian, Yiying, Liu, Shengnan, Fu, Jingqi, Sun, Yongxin, Li, Jiliang, Yamamoto, Masayuki, Zhang, Qiang, Xu, Yuanyuan, Pi, Jingbo

“…Fine-tuning of osteoclast differentiation (OD) and bone remodeling is crucial for bone homeostasis. Dissecting the mechanisms regulating osteoclastogenesis is…”
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The presence of busulfan metabolites and pharmacometabolomics in plasma drawn immediately before allograft infusion in hematopoietic cell transplant recipients by McCune, Jeannine S., Navarro, Sandi L., Risler, Linda J., Phillips, Brian R., Ren, Suping, Schoch, H. Gary, Baker, K. Scott

“…Busulfan is hepatically metabolized through glutathione (GSH) conjugation; in vitro, this process depletes hepatocyte GSH stores and generates the cytotoxic…”
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Challenges with sirolimus experimental data to inform QSP model of post‐transplantation cyclophosphamide regimens by Mohanan, Ezhilpavai, Shen, Guofang, Ren, Suping, Fan, Hsuan‐Hao, Moua, Kao Tang Ying, Karolak, Aleksandra, Rockne, Russell C., Nakamura, Ryotaro, Horne, David A., Kanakry, Christopher G., Mager, Donald E., McCune, Jeannine S.

“…Dose optimization of sirolimus may further improve outcomes in allogeneic hematopoietic cell transplant (HCT) patients receiving post‐transplantation…”
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