Search Results - "Suopanki, J."

An arginine/lysine-rich motif is crucial for VCP/p97-mediated modulation of ataxin-3 fibrillogenesis by Boeddrich, Annett, Gaumer, Sébastien, Haacke, Annette, Tzvetkov, Nikolay, Albrecht, Mario, Evert, Bernd O, Müller, Eva C, Lurz, Rudi, Breuer, Peter, Schugardt, Nancy, Plaßmann, Stephanie, Xu, Kexiang, Warrick, John M, Suopanki, Jaana, Wüllner, Ullrich, Frank, Ronald, Hartl, Ulrich F, Bonini, Nancy M, Wanker, Erich E

“…Arginine/lysine‐rich motifs typically function as targeting signals for the translocation of proteins to the nucleus. Here, we demonstrate that such a motif…”
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Status Epilepticus Induces Changes in the Expression and Localization of Endogenous Palmitoyl-Protein Thioesterase 1 by Suopanki, J., Lintunen, M., Lahtinen, H., Haltia, M., Panula, P., Baumann, M., Tyynelä, J.

“…Kainic acid (KA)-induced experimental epilepsy, a model of excitotoxicity, leads to selective neuronal death and synaptic restructuring. We used this model to…”
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Variant Late Infantile Neuronal Ceroid-lipofuscinosis: Pathology and Biochemistry by TYYNELÄ, J, SUOPANKI, J, SANTAVUORI, P, BAUMANN, M, HALTIA, M

“…The neuronal ceroid-lipofuscinoses (NCL) are among the most common inherited neurodegenerative disorders of childhood. The genomic defect causing a variant…”
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The Expression of Palmitoyl-Protein Thioesterase Is Developmentally Regulated in Neural Tissues but Not in Nonneural Tissues by Suopanki, Jaana, Tyynelä, Jaana, Baumann, Marc, Haltia, Matti

“…Mutations in a palmitoyl-protein thioesterase (PPT) gene cause infantile neuronal ceroid lipofuscinosis (INCL). INCL is characterized by an extreme and…”
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Hippocampal lesions in the neuronal ceroid lipofuscinoses by Haltia, M, Herva, R, Suopanki, J, Baumann, M, Tyynelä, J

“…Epilepsy is a common manifestation in all childhood-onset forms of neuronal ceroid lipofuscinosis. In order to document hippocampal lesions and their…”
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Biochemical aspects of neuronal ceroid lipofuscinoses by Tyynelä, J, Suopanki, J

“…The neuronal ceroid lipofuscinoses (NCLs) collectively constitute the most common group of progressive brain diseases in children. The childhood forms of NCL…”
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Sphingolipid activator proteins (SAPs) in neuronal ceroid lipofuscinoses (NCL) by Tyynelä, J, Suopanki, J, Baumann, M, Haltia, M

“…Based on the predominant component of the storage material the neuronal ceroid lipofuscinoses (NCL) can be divided into two categories: one storing…”
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A Protein Interaction Network Links GIT1, an Enhancer of Huntingtin Aggregation, to Huntington's Disease by Goehler, Heike, Lalowski, Maciej, Stelzl, Ulrich, Waelter, Stephanie, Stroedicke, Martin, Worm, Uwe, Droege, Anja, Lindenberg, Katrin S., Knoblich, Maria, Haenig, Christian, Herbst, Martin, Suopanki, Jaana, Scherzinger, Eberhard, Abraham, Claudia, Bauer, Bianca, Hasenbank, Renate, Fritzsche, Anja, Ludewig, Andreas H., Buessow, Konrad, Coleman, Sarah H., Gutekunst, Claire-Anne, Landwehrmeyer, Bernhard G., Lehrach, Hans, Wanker, Erich E.

“…Analysis of protein-protein interactions (PPIs) is a valuable approach for characterizing proteins of unknown function. Here, we have developed a strategy…”
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Interaction of huntingtin fragments with brain membranes – clues to early dysfunction in Huntington's disease by Suopanki, Jaana, Götz, Claudia, Lutsch, Gudrun, Schiller, Jürgen, Harjes, Phoebe, Herrmann, Andreas, Wanker, Erich E.

“…Huntingtin is a large, multi‐domain protein of unknown function in the brain. An abnormally elongated polyglutamine stretch in its N‐terminus causes…”
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Immunological mapping of the human leucocyte adhesion glycoprotein gp90 (CD18) by monoclonal antibodies by Nortamo, P, Patarroyo, M, Kantor, C, Suopanki, J, Gahmberg, C G

“…The leucocyte surface glycoproteins CD11a (gp160, LFA-1 antigen, TA-1 antigen), CD11b (gp155, Mac-1 antigen, OKM1 antigen, Mo-1 antigen), CD11c (gp130, Leu-M5…”
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Enzymatic in vitro synthesis of radiolabeled pentasaccharides GlcNAc beta 1-3(Gal beta 1-4GlcNAc beta 1-6)Gal beta 1-4GlcNAc/Glc and the isomeric Gal beta 1-4GlcNAc beta 1-3(GlcNAc beta 1-6)Gal beta 1-4GlcNAc/Glc by Renkonen, O, Leppänen, A, Niemelä, R, Vilkman, A, Helin, J, Penttilä, L, Maaheimo, H, Seppo, A, Suopanki, J

“…Four radiolabeled pentasaccharides, GlcNAc beta 1-3(Gal beta 1-4GlcNAc beta 1-6)Gal beta 1-4GlcNAc, Gal beta 1-4GlcNAc beta 1-3(GlcNAc beta 1-6)Gal beta…”
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0006 The Pharmacokinetics and Pharmacodynamics of SM-1 by Dahl, T, Roth, T, Scheinin, M, Suopanki-Lalowski, J, Valge, M, Puhakka, A, Mikola, H, Lovró, Z, Meierjohann, A, Vuorilehto, L, Chen, L

“…Abstract Introduction The most common form of sleep disturbance is transient insomnia, and in parallel the most common pattern of use for hypnotic medications…”
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Palmitoyl-protein thioesterase, an enzyme implicated in neurodegeneration, is localized in neurons and is developmentally regulated in rat brain by Suopanki, Jaana, Tyynelä, Jaana, Baumann, Marc, Haltia, Matti

“…Palmitoyl-protein thioesterase (PPT) is an enzyme involved in cleavage of palmitate residues from acylated proteins. Mutations in PPT gene cause a severe…”
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Regulation of alphavirus 26S mRNA transcription by replicase component nsP2 by Suopanki, J, Sawicki, DL, Sawicki, SG, Kaariainen, L

“…J Suopanki, DL Sawicki, SG Sawicki and L Kaariainen Biocenter Viikki, Institute of Biotechnology, University of Helsinki, Finland. jaana.suopanki@helsinki.fi…”
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A Protein Interaction Network Links GIT1, an Enhancer of Huntingtin Aggregation, to Huntington’s Disease by Goehler, Heike, Lalowski, Maciej, Stelzl, Ulrich, Waelter, Stephanie, Stroedicke, Martin, Worm, Uwe, Droege, Anja, Lindenberg, Katrin S., Knoblich, Maria, Haenig, Christian, Herbst, Martin, Suopanki, Jaana, Scherzinger, Eberhard, Abraham, Claudia, Bauer, Bianca, Hasenbank, Renate, Fritzsche, Anja, Ludewig, Andreas H., Buessow, Konrad, Coleman, Sarah H., Gutekunst, Claire-Anne, Landwehrmeyer, Bernhard G., Lehrach, Hans, Wanker, Erich E.

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Developmental Changes in the Expression of Neuronal Ceroid Lipofuscinoses-Linked Proteins by Suopanki, Jaana, Partanen, Sanna, Ezaki, Junji, Baumann, Marc, Kominami, Eiki, Tyynelä, Jaana

“…Neuronal ceroid lipofuscinoses (NCL) form a distinct group of storage diseases where the normal development of the central nervous system is interrupted and…”
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