Search Results - "Suomela, Sari"
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NOD-like receptor signaling and inflammasome-related pathways are highlighted in psoriatic epidermis
Published in Scientific reports (15-03-2016)“…Psoriatic skin differs distinctly from normal skin by its thickened epidermis. Most gene expression comparisons utilize full-thickness biopsies, with…”
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2
Identification of novel miRNA‐mRNA regulatory networks in contact dermatitis by integrated microarray analysis
Published in Allergy (Copenhagen) (01-04-2021)Get full text
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Intracellular signalling pathways and cytoskeletal functions converge on the psoriasis candidate gene CCHCR1 expressed at P-bodies and centrosomes
Published in BMC genomics (04-06-2018)“…CCHCR1 (Coiled-Coil α-Helical Rod protein 1) is a putative psoriasis candidate gene with the risk alleles CCHCR1*WWCC and *Iso3, the latter inhibiting the…”
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4
Centrosomal localization of the psoriasis candidate gene product, CCHCR1, supports a role in cytoskeletal organization
Published in PloS one (26-11-2012)“…CCHCR1 (Coiled-Coil α-Helical Rod protein 1), within the major psoriasis susceptibility locus PSORS1, is a plausible candidate gene with the psoriasis…”
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5
Occupational contact urticaria due to diethylphthalate in hand sanitizers
Published in Contact dermatitis (01-01-2023)Get full text
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6
CCHCR1 is up-regulated in skin cancer and associated with EGFR expression
Published in PloS one (24-06-2009)“…Despite chronic inflammation, psoriatic lesions hardly ever progress to skin cancer. Aberrant function of the CCHCR1 gene (Coiled-Coil alpha-Helical Rod…”
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The CCHCR1 (HCR) gene is relevant for skin steroidogenesis and downregulated in cultured psoriatic keratinocytes
Published in Journal of molecular medicine (Berlin, Germany) (01-06-2007)“…The HCR gene, officially called Coiled-Coil alpha-Helical Rod protein 1 (CCHCR1), located within the major psoriasis susceptibility locus PSORS1, is a…”
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8
IL23R in the Swedish, Finnish, Hungarian and Italian populations: association with IBD and psoriasis, and linkage to celiac disease
Published in BMC medical genetics (28-01-2009)“…Association of the interleukin-23 receptor (IL23R) with inflammatory bowel disease (IBD) has been confirmed in several populations. IL23R also associates with…”
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9
Allergic contact dermatitis caused by colophonium in resin creams
Published in Contact dermatitis (01-07-2024)Get full text
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10
Occupational IgE‐mediated psyllium allergy in contemporary gluten‐free and vegan baking: A case of allergic rhinitis
Published in American journal of industrial medicine (01-05-2021)“…Psyllium (from Plantago ovata; ispaghula) is used as a dietary supplement and is supplied in the form of husk, granules, capsules, or powder. Consumers using…”
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11
Occupational contact allergy to benzyl alcohol in epoxy hardeners
Published in Contact dermatitis (01-12-2023)Get full text
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12
Nine years of patch testing with isocyanates in a clinic of occupational dermatology
Published in Contact dermatitis (01-09-2024)“…Background Isocyanates are used as starting materials of polyurethane (PU) products. They are relatively important occupational skin sensitizers. Objectives To…”
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13
The CCHCR1 (HCR) gene is relevant for skin steroidogenesis and downregulated in cultured psoriatic keratinocytes
Published in Journal of molecular medicine (Berlin, Germany) (01-06-2007)Get full text
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14
Characterization of patients with occupational allergy to two new epoxy hardener compounds
Published in Contact dermatitis (01-07-2022)“…Background The practical importance of two recently described epoxy hardener allergens—1,3‐benzenedimethanamine, N‐(2‐phenylethyl) derivatives (1,3‐BDMA‐D) and…”
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15
Occupational allergic contact dermatitis caused by colophonium
Published in Contact dermatitis (01-01-2019)“…Background Colophonium is a common contact allergen that is present not only in household products but also in occupational settings. Objectives To describe…”
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16
Machine-learning–driven biomarker discovery for the discrimination between allergic and irritant contact dermatitis
Published in Proceedings of the National Academy of Sciences - PNAS (29-12-2020)“…Contact dermatitis tremendously impacts the quality of life of suffering patients. Currently, diagnostic regimes rely on allergy testing, exposure…”
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Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity
Published in Nature genetics (01-12-2012)“…Richard Trembath and colleagues report a meta-analysis of genome-wide association studies for psoriasis, including 2 cohorts genotyped on the custom Immunochip…”
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18
High prevalence of sensitization to bumblebee venom among greenhouse workers
Published in The journal of allergy and clinical immunology in practice (Cambridge, MA) (01-02-2022)“…Clinical Implications Sensitization to bumblebee venom is common among workers in greenhouses that use bumblebees for pollination and seems to be associated…”
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Occupational asthma, rhinitis, and contact urticaria from indigo (Indigofera tinctoria) hair dye
Published in The journal of allergy and clinical immunology in practice (Cambridge, MA) (01-09-2021)“…An open skin application test result for indigo was negative. Because of mild rhinitis symptoms, tests for occupational rhinitis were not performed…”
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Prevalence of tomato and cucumber sensitization among greenhouse workers
Published in The journal of allergy and clinical immunology in practice (Cambridge, MA) (01-02-2022)“…Vegetables have been reported to cause occupational allergic diseases for example in kitchen and food industry work.1,2 Cases of occupational asthma, rhinitis,…”
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