Search Results - "Sunil, S."
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Sex differential in COVID-19 mortality varies markedly by age
Published in The Lancet (British edition) (22-08-2020)“…In the COVID-19 pandemic, we have emphasised the importance for epidemiological data to be presented by age and sex groups.1,2 This call has also been made by…”
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Cyclodextrins in pharmaceutical formulations I: structure and physicochemical properties, formation of complexes, and types of complex
Published in Drug discovery today (01-02-2016)“…•Cyclodextrins and the complexes they form are described.•Pharmaceutical uses of cyclodextrin are enumerated.•Physical chemical properties of cyclodextrins are…”
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3
Racism and discrimination in COVID-19 responses
Published in The Lancet (British edition) (11-04-2020)Get full text
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Cyclodextrins in pharmaceutical formulations II: solubilization, binding constant, and complexation efficiency
Published in Drug discovery today (01-02-2016)“…•Determination and significance of the binding constant is described.•The complexation efficiency and its utility are discussed.•The use of cyclodextrin in the…”
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Large-scale production of enzymes for biotechnology uses
Published in Current opinion in biotechnology (01-06-2021)“…[Display omitted] Enzymes are biocatalysts that speed up the chemical reaction to obtain the final valuable product/s. Biotechnology has revolutionized the use…”
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Children and young people remain at low risk of COVID-19 mortality
Published in The lancet child & adolescent health (01-05-2021)Get more information
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Tracking tsunami propagation and Island’s collapse after the Hunga Tonga Hunga Ha’apai 2022 volcanic eruption from multi-space observations
Published in Scientific reports (17-11-2023)“…The quantity and accuracy of satellite-geodetic measurements have increased over time, revolutionizing the monitoring of tectonic processes. Global Navigation…”
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Risk and the South Asian monsoon
Published in Climatic change (01-11-2018)“…South Asia’s dependence on the monsoon has always been a source of economic uncertainty. This paper examines the history of ways of thinking about the monsoon…”
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9
Quantitative profiling brain proteomes revealed mitochondrial dysfunction in Alzheimer's disease
Published in Molecular brain (28-01-2019)“…Mitochondrial dysfunction is a key feature in both aging and neurodegenerative diseases including Alzheimer's disease (AD), but the molecular signature that…”
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CIBERSORT analysis of TCGA and METABRIC identifies subgroups with better outcomes in triple negative breast cancer
Published in Scientific reports (25-02-2021)“…Studies have shown that the presence of tumor infiltrating lymphocytes (TILs) in Triple Negative Breast Cancer (TNBC) is associated with better prognosis…”
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Recent omics advances in hair aging biology and hair biomarkers analysis
Published in Ageing research reviews (01-11-2023)“…Aging is a complex natural process that leads to a decline in physiological functions, which is visible in signs such as hair graying, thinning, and loss…”
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Targeting T cell malignancies using CAR-based immunotherapy: challenges and potential solutions
Published in Journal of hematology and oncology (29-12-2019)“…Chimeric antigen receptor (CAR) T cell therapy has been successful in treating B cell malignancies in clinical trials; however, fewer studies have evaluated…”
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Prognostic value of tumor-infiltrating lymphocytes in triple-negative breast cancers from two phase III randomized adjuvant breast cancer trials: ECOG 2197 and ECOG 1199
Published in Journal of clinical oncology (20-09-2014)“…Recent studies suggest that tumor-infiltrating lymphocytes (TILs) are associated with disease-free (DFS) and overall survival (OS) in operable triple-negative…”
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Targeting the Tumor-Tumor Microenvironment Crosstalk
Published in Expert opinion on therapeutic targets (2023)“…Cancer development and progression is a complex process influenced by co-evolution of the cancer cells and their microenvironment. However, traditional…”
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Metabolomics Signatures of Aging: Recent Advances
Published in Aging and disease (01-04-2021)“…Metabolomics is the latest state-of-the-art omics technology that provides a comprehensive quantitative profile of metabolites. The metabolites are the…”
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Micro (nano) plastics in wastewater: A critical review on toxicity risk assessment, behaviour, environmental impact and challenges
Published in Chemosphere (Oxford) (01-03-2022)“…With millions of tonnes of plastic pollution generated every year, small-sized plastic particles, including micro- and nanoplastics, end up in freshwater…”
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Using Small Molecules for Targeting Heavy Metals in Neurotoxicity and Neuroinflammation
Published in Methods in molecular biology (Clifton, N.J.) (2024)“…Pharmaceutical drugs, natural toxins, industrial chemicals, and various environmental toxins negatively impact the nervous system. A significant cause of many…”
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COVID-19: the great unequaliser
Published in Journal of the Royal Society of Medicine (01-06-2020)Get full text
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C5 Inhibitor Avacincaptad Pegol for Geographic Atrophy Due to Age-Related Macular Degeneration: A Randomized Pivotal Phase 2/3 Trial
Published in Ophthalmology (Rochester, Minn.) (01-04-2021)“…The complement pathway may play a key role in the pathogenesis of age-related macular degeneration (AMD). The safety and efficacy of avacincaptad pegol…”
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Volcanic Eruption Triggers a Rare Meteotsunami in the Indian Ocean
Published in Geophysical research letters (28-01-2024)“…This study presents the observation and evaluation of a meteotsunami in the Indian Ocean triggered by the Hunga‐Tonga volcanic eruption. The event was detected…”
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