Clinical and demographic evaluation of Behçet disease among different paediatric age groups

The aim of the study is to describe the demographic and clinical features of Behçet disease (BD) in paediatric patients. The study included 62 patients who presented to the Department of Ophthalmology at Ankara Education and Research Hospital, Ankara, Turkey and diagnosed as having BD. These patient...

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Bibliographic Details
Published in:	British journal of ophthalmology Vol. 93; no. 1; p. 83
Main Authors:	Sungur, G K, Hazirolan, D, Yalvac, I, Ozer, P A, Yuksel, D, Vural, E T, Duman, S
Format:	Journal Article
Language:	English
Published:	England 01-01-2009
Subjects:	Adolescent Age of Onset Behcet Syndrome - complications Behcet Syndrome - epidemiology Behcet Syndrome - therapy Child Child, Preschool Diagnosis, Differential Eye Diseases - epidemiology Eye Diseases - etiology Family Health Female Genetic Testing Humans Infant Infant, Newborn Male Oral Ulcer - epidemiology Retrospective Studies Sex Distribution Sex Factors Turkey - epidemiology Young Adult Turkey
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Summary:	The aim of the study is to describe the demographic and clinical features of Behçet disease (BD) in paediatric patients. The study included 62 patients who presented to the Department of Ophthalmology at Ankara Education and Research Hospital, Ankara, Turkey and diagnosed as having BD. These patients were placed into three age groups based on the age at the time of BD presentation: group 1, birth to 10 years old; group 2, 11-15 years old; group 3, 16-20 years old. Among these three age groups, the objective was to identify the ocular and extraocular clinical findings and complications of BD, and to uncover the role of gender, if exists, in the aetiology of the disease. The findings indicated that gender played no significant role in the aetiology of BD. In group 1, a family history of BD was more prevalent, and the most common ocular finding was bilateral anterior uveitis. The most frequent form of ocular involvement in groups 2 and 3 was bilateral panuveitis with retinal vasculitis and retinitis. The majority of disease complications were glaucoma, maculopathy and cataract formation. Patient age appeared to define the type of ocular involvement in BD. While anterior uveitis was the most frequent ocular finding in BD patients younger than 10 years, panuveitis was the most frequent in patients older than 10 years. As a family history of BD was more frequent among patients younger than 10 years, family screening for BD is considered critical for early and accurate diagnosis of BD, as well as for the control of its complications.
ISSN:	1468-2079
DOI:	10.1136/bjo.2007.137141