Search Results - "Sungjin Chung"

Effect of Sodium-Glucose Co-Transporter 2 Inhibitor, Dapagliflozin, on Renal Renin-Angiotensin System in an Animal Model of Type 2 Diabetes by Shin, Seok Joon, Chung, Sungjin, Kim, Soo Jung, Lee, Eun-Mi, Yoo, Young-Hye, Kim, Ji-Won, Ahn, Yu-Bae, Kim, Eun-Sook, Moon, Sung-Dae, Kim, Myung-Jun, Ko, Seung-Hyun

“…Renal renin-angiotensin system (RAS) activation is one of the important pathogenic mechanisms in the development of diabetic nephropathy in type 2 diabetes…”
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Inhibition of p300/CBP-Associated Factor Attenuates Renal Tubulointerstitial Fibrosis through Modulation of NF-kB and Nrf2 by Chung, Sungjin, Kim, Soojeong, Son, Mina, Kim, Minyoung, Koh, Eun Sil, Shin, Seok Joon, Park, Cheol Whee, Kim, Ho-Shik

“…p300/CBP-associated factor (PCAF), a histone acetyltransferase, is involved in many cellular processes such as differentiation, proliferation, apoptosis, and…”
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Adiponectin receptor agonist ameliorates cardiac lipotoxicity via enhancing ceramide metabolism in type 2 diabetic mice by Kim, Yaeni, Lim, Ji Hee, Kim, Eun Nim, Hong, Yu Ah, Park, Hun-Jun, Chung, Sungjin, Choi, Bum Soon, Kim, Yong-Soo, Park, Ji Yong, Kim, Hye Won, Park, Cheol Whee

“…Accumulation of lipids and their metabolites induces lipotoxicity in diabetic cardiomyopathy. Lowering ceramide concentration could reduce the impact of…”
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Use of Anti-Diabetic Agents in Non-Diabetic Kidney Disease: From Bench to Bedside by Chung, Sungjin, Kim, Gheun-Ho

“…New drugs were recently developed to treat hyperglycemia in patients with type 2 diabetes mellitus (T2D). However, metformin remains the first-line…”
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Modeling of Fabry disease nephropathy using patient derived human induced pluripotent stem cells and kidney organoid system by Cui, Sheng, Fang, Xianying, Lee, Hanbi, Shin, Yoo Jin, Koh, Eun-Sil, Chung, Sungjin, Park, Hoon Suk, Lim, Sun Woo, Lee, Kang In, Lee, Jae Young, Yang, Chul Woo, Chung, Byung Ha

“…To explore the possibility of kidney organoids generated using patient derived human induced pluripotent stem cells (hiPSC) for modeling of Fabry disease…”
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Fenofibrate improves renal lipotoxicity through activation of AMPK-PGC-1α in db/db mice by Hong, Yu Ah, Lim, Ji Hee, Kim, Min Young, Kim, Tae Woo, Kim, Yaeni, Yang, Keun Suk, Park, Hoon Suk, Choi, Sun Ryoung, Chung, Sungjin, Kim, Hyung Wook, Kim, Hye Won, Choi, Bum Soon, Chang, Yoon Sik, Park, Cheol Whee

“…Peroxisome proliferator-activated receptor (PPAR)-α, a lipid-sensing transcriptional factor, serves an important role in lipotoxicity. We evaluated whether…”
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Therapeutic roles of thiazides and loop diuretics in blood pressure control and renal protection against chronic kidney disease by Jo, Wonji, Koh, Eun Sil, Chung, Sungjin

“…Fluid overload secondary to loss of functional nephron mass can elevate blood pressure, which is characteristic of hypertension shown in chronic kidney disease…”
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Inhibition of lymphatic proliferation by the selective VEGFR-3 inhibitor SAR131675 ameliorates diabetic nephropathy in db/db mice by Hwang, Seun Deuk, Song, Joon Ho, Kim, Yaeni, Lim, Ji Hee, Kim, Min Young, Kim, Eun Nim, Hong, Yu Ah, Chung, Sungjin, Choi, Bum Soon, Kim, Yong-Soo, Park, Cheol Whee

“…Recent studies have demonstrated that chronic inflammation-induced lymphangiogenesis plays a crucial role in the progression of various renal diseases,…”
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Intrarenal Mechanisms of Sodium-Glucose Cotransporter-2 Inhibitors on Tubuloglomerular Feedback and Natriuresis by Koh, Eun Sil, Kim, Gheun-Ho, Chung, Sungjin

“…When sodium-glucose cotransporter-2 (SGLT2) inhibitors were first introduced a decade ago, no one expected them to have substantial effects beyond their known…”
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Urate Transporters in the Kidney: What Clinicians Need to Know by Sungjin Chung, Gheun-ho Kim

“…Urate is produced in the liver by the degradation of purines from the diet and nucleotide turnover and excreted by the kidney and gut. The kidney is the major…”
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Author Correction: Importance of dialysis specialists in early mortality in elderly hemodialysis patients: a multicenter retrospective cohort study by Park, Yohan, Lee, Ji Won, Yoon, Se-Hee, Yun, Sung-Ro, Kim, Hyunsuk, Bae, Eunjin, Hyun, Young Youl, Chung, Sungjin, Kwon, Soon Hyo, Cho, Jang-Hee, Yoo, Kyung Don, Park, Woo Yeong, Sun, In O, Yu, Byung Chul, Ko, Gang-Jee, Yang, Jae Won, Song, Sang Heon, Shin, Sung Joon, Hong, Yu Ah, Hwang, Won Min

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Progressive rise in red blood cell distribution width predicts mortality and cardiovascular events in end-stage renal disease patients by Yoon, Hye Eun, Kim, Sung Jun, Hwang, Hyeon Seok, Chung, Sungjin, Yang, Chul Woo, Shin, Seok Joon

“…Red blood cell distribution width (RDW) is a robust marker of adverse clinical outcomes in various populations. However, the clinical significance of a…”
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Treatment combining aliskiren with paricalcitol is effective against progressive renal tubulointerstitial fibrosis via dual blockade of intrarenal renin by Chung, Sungjin, Kim, Soojeong, Kim, Minyoung, Koh, Eun Sil, Shin, Seok Joon, Park, Cheol Whee, Chang, Yoon Sik, Kim, Ho-Shik

“…The aim of this study was to assess any potential additive effects of a treatment combining aliskiren with paricalcitol on reducing renal fibrosis. C57BL/6J…”
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Empagliflozin Contributes to Polyuria via Regulation of Sodium Transporters and Water Channels in Diabetic Rat Kidneys by Chung, Sungjin, Kim, Soojeong, Son, Mina, Kim, Minyoung, Koh, Eun Sil, Shin, Seok Joon, Ko, Seung-Hyun, Kim, Ho-Shik

“…Besides lowering glucose, empagliflozin, a selective sodium-glucose cotransporter-2 (SGLT2) inhibitor, have been known to provide cardiovascular and renal…”
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The Protective Effect of Zebularine, an Inhibitor of DNA Methyltransferase, on Renal Tubulointerstitial Inflammation and Fibrosis by Koh, Eun Sil, Kim, Soojeong, Son, Mina, Park, Ji-Young, Pyo, Jaehyuk, Kim, Wan-Young, Kim, Minyoung, Chung, Sungjin, Park, Cheol Whee, Kim, Ho-Shik, Shin, Seok Joon

“…Renal fibrosis, the final pathway of chronic kidney disease, is caused by genetic and epigenetic mechanisms. Although DNA methylation has drawn attention as a…”
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Importance of dialysis specialists in early mortality in elderly hemodialysis patients: a multicenter retrospective cohort study by Park, Yohan, Lee, Ji Won, Yoon, Se-Hee, Yun, Sung-Ro, Kim, Hyunsuk, Bae, Eunjin, Hyun, Young Youl, Chung, Sungjin, Kwon, Soon Hyo, Cho, Jang-Hee, Yoo, Kyung Don, Park, Woo Yeong, Sun, In O, Yu, Byung Chul, Ko, Gang-Jee, Yang, Jae Won, Song, Sang Heon, Shin, Sung Joon, Hong, Yu Ah, Hwang, Won Min

“…The early mortality rate in elderly patients undergoing hemodialysis is more than twice that in young patients, requiring more specialized healthcare. We…”
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Results from a cross-specialty consensus on optimal management of patients with chronic kidney disease (CKD): from screening to complications by Arici, Mustafa, Assaad-Khalil, Samir Helmy, Bertoluci, Marcello Casaccia, Choo, Jason, Lee, Yau-Jiunn, Madero, Magdalena, Rosa Diez, Guillermo Javier, Sánchez Polo, Vicente, Chung, Sungjin, Thanachayanont, Teerawat, Pollock, Carol

“…BackgroundChronic kidney disease (CKD) affects around 10% of the global population and has been estimated to affect around 50% of individuals with type 2…”
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High-fat diet-induced renal cell apoptosis and oxidative stress in spontaneously hypertensive rat are ameliorated by fenofibrate through the PPARα―FoxO3a―PGC-1α pathway by HYUN WHA CHUNG, JI HEE LIM, MIN YOUNG KIM, SEOK JOON SHIN, SUNGJIN CHUNG, BUM SOON CHOI, HYUNG WOOK KIM, KIM, Yong-Soo, CHEOL WHEE PARK, YOON SIK CHANG

“…The peroxisome proliferator-activated receptor-α (PPARα) is a lipid-sensing transcriptional factor that has a role in gluco-oxidative stress and lipotoxicity…”
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Intrarenal Mechanisms of Sodium-Glucose Cotransporter-2 Inhibitors on Tubuloglomerular Feedback and Natriuresis by Eun Sil Koh, Gheun-ho Kim, Sungjin Chung

“…When sodium-glucose cotransporter-2 (SGLT2) inhibitors were first introduced a decade ago, no one expected them to have substantial effects beyond their known…”
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Altered Metabolism of Blood Manganese Is Associated with Low Levels of Hemoglobin in Patients with Chronic Kidney Disease by Kim, Minyoung, Koh, Eun Sil, Chung, Sungjin, Chang, Yoon Sik, Shin, Seok Joon

“…Blood manganese (Mn) level has been reported to be higher in patients with anemia or iron deficiency. The purpose of this study was to analyze the relationship…”
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