Search Results - "Sunga, Gemalene"

Enhancement of Immunotherapies in Head and Neck Cancers Using Biomaterial-Based Treatment Strategies by Sunga, Gemalene M, Hartgerink, Jeffrey, Sikora, Andrew G, Young, Simon

“…Head and neck squamous cell carcinoma (HNSCC) is a challenging disease to treat because of typically late-stage diagnoses and tumor formation in…”
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A Flow Cytometry-Based Cytotoxicity Assay for the Assessment of Human NK Cell Activity by Kandarian, Fadi, Sunga, Gemalene M, Arango-Saenz, Diana, Rossetti, Maura

“…Within the innate immune system, effector lymphocytes known as natural killer (NK) cells play an essential role in host defense against aberrant cells,…”
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Localized intratumoral delivery of immunomodulators for oral cancer and oral potentially malignant disorders by Hussein, Nourhan I., Molina, Andrea H., Sunga, Gemalene M., Amit, Moran, Lei, Yu Leo, Zhao, Xiao, Hartgerink, Jeffrey D., Sikora, Andrew G., Young, Simon

“…•Systemic delivery of current cancer immunotherapies are limited by adverse effects.•Localized intratumoral delivery approaches can mitigate current…”
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NK and CD8+ T cell phenotypes predict onset and control of CMV viremia after kidney transplant by Pickering, Harry, Sen, Subha, Arakawa-Hoyt, Janice, Ishiyama, Kenichi, Sun, Yumeng, Parmar, Rajesh, Ahn, Richard S, Sunga, Gemalene, Llamas, Megan, Hoffmann, Alexander, Deng, Mario, Bunnapradist, Suphamai, Schaenman, Joanna M, Gjertson, David W, Rossetti, Maura, Lanier, Lewis L, Reed, Elaine F

“…CMV causes mostly asymptomatic but lifelong infection. Primary infection or reactivation in immunocompromised individuals can be life-threatening. CMV viremia…”
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Circulating immune cell phenotype dynamics reflect the strength of tumor–immune cell interactions in patients during immunotherapy by Griffiths, Jason I., Wallet, Pierre, Pflieger, Lance T., Stenehjem, David, Liu, Xuan, Cosgrove, Patrick A., Leggett, Neena A., McQuerry, Jasmine A., Shrestha, Gajendra, Rossetti, Maura, Sunga, Gemalene, Moos, Philip J., Adler, Frederick R., Chang, Jeffrey T., Sharma, Sunil, Bild, Andrea H.

“…The extent to which immune cell phenotypes in the peripheral blood reflect within-tumor immune activity prior to and early in cancer therapy is unclear. To…”
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T cell senescence and impaired CMV-specific response are associated with infection risk in kidney transplant recipients by Pickering, Harry, Schaenman, Joanna, Rossetti, Maura, Ahn, Richard, Sunga, Gemalene, Liang, Emily C., Bunnapradist, Suphamai, Reed, Elaine F.

“…Older kidney transplant recipients demonstrate increased rates of infection, and lower rates of rejection, compared with younger kidney transplant recipients…”
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Corrigendum to “T cell senescence and impaired CMV-specific response are associated with infection risk in kidney transplant recipients” [Hum. Immunol. 83(4) (2022) 273–280] by Pickering, Harry, Schaenman, Joanna, Rossetti, Maura, Ahn, Richard, Sunga, Gemalene, Liang, Emily C., Bunnapradist, Suphamai, Reed, Elaine F.

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Identification of Plasma Protein Biomarkers of Acute Renal Allograft Rejection by Rossetti, Maura, Fitzpatrick, Connor, Harre, Nicholas, Zheng, Ying, Mercer, Neil, Sunga, Gemalene, Gjertson, David, Reed, Elaine

“…Upon presentation of clinical symptoms, renal transplant recipients routinely undergo needle core biopsy to diagnose acute graft rejection. This procedure is…”
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A screen of Crohn’s disease-associated microbial metabolites identifies ascorbate as a novel metabolic inhibitor of activated human T cells by Chang, Yu-Ling, Rossetti, Maura, Vlamakis, Hera, Casero, David, Sunga, Gemalene, Harre, Nicholas, Miller, Shelley, Humphries, Romney, Stappenbeck, Thaddeus, Simpson, Kenneth W., Sartor, R. Balfour, Wu, Gary, Lewis, James, Bushman, Frederic, McGovern, Dermot P. B., Salzman, Nita, Borneman, James, Xavier, Ramnik, Huttenhower, Curtis, Braun, Jonathan

“…Microbial metabolites are an emerging class of mediators influencing CD4 + T-cell function. To advance the understanding of direct causal microbial factors…”
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A Flow Cytometry-Based Cytotoxicity Assay for the Assessment of Human NK Cell Activity by Kandarian, Fadi, Sunga, Gemalene M, Arango-Saenz, Diana, Rossetti, Maura

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638. CMV-Specific T-Cell Immune Responses in Older vs. Younger Kidney Transplant Recipients by Liang, Emily, Rossetti, Maura, Sunga, Gemalene, Reed, Elaine, Schaenman, Joanna

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Preservation of Antiviral Immunologic Efficacy Without Alloimmunity After Switch to Belatacept in Calcineurin Inhibitor–Intolerant Patients by Schaenman, Joanna, Rossetti, Maura, Pickering, Harry, Sunga, Gemalene, Wilhalme, Holly, Elashoff, David, Zhang, Qiuheng, Hickey, Michelle, Reddy, Uttam, Danovitch, Gabriel, Reed, Elaine F., Bunnapradist, Suphamai

“…Belatacept has shown potential for prevention of rejection after kidney transplantation, given its demonstration of reduced nephrotoxicity in combination with…”
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OR18 Identification of anti-endothelial non–HLA antibodies in kidney allograft rejection by Butler, Carrie, Zhang, Qiuheng, Jiang, Ning, Pearl, Meghan, Rossetti, Maura, Sunga, Gemalene, Kandaian, Fadi, Ray, Bryan L., Reed, Elaine F.

“…The endothelium is the initial point of contact between the donor allograft and the transplant recipient’s immune system and therefore is a likely source for…”
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OR13 Identification and characterization of a panel of non–HLA antibodies in kidney allograft rejection by Butler, Carrie L., Hickey, Michelle J., Gjertson, David W., Pearl, Meghan, Rossetti, Maura, Cecka, J. Michael, Kandarian, Fadi, Sunga, Gemalene, Zhang, Qiuheng, Ray, Bryan L., Reed, Elaine F.

“…The goal of this study was to identify novel anti-endothelial non–HLA antibodies (Ab) associated with kidney allograft rejection and assess a panel of novel…”
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Association of pro-inflammatory cytokines and monocyte subtypes in older and younger patients on clinical outcomes after mechanical circulatory support device implantation by Schaenman, Joanna M., Rossetti, Maura, Sidwell, Tiffany, Groysberg, Victoria, Sunga, Gemalene, Liang, Emily, Vangala, Sitaram, Chang, Eleanor, Bakir, Maral, Bondar, Galyna, Cadeiras, Martin, Kwon, Murray, Reed, Elaine F., Deng, Mario

“…Noninvasive immunologic analysis of peripheral blood holds promise for explaining the mechanism of development of adverse clinical outcomes, and may also…”
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P033 Quantification of CMV-specific T cell responses in immunosuppressed renal transplant recipients by Rossetti, Maura, Korin, Yael, Sidwell, Tiffany, Sunga, Gemalene, Harre, Nicholas, Sigdel, Tara, Bunnapradist, Suphamai, Vincenti, Flavio, Sarwal, Minnie, Reed, Elaine

“…Aim Cytomegalovirus (CMV) is one of the most problematic pathogens in the immunocompromised host after solid organ and stem cell transplantation, increasing…”
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Mutational landscape influences immunotherapy outcomes among patients with non-small-cell lung cancer with human leukocyte antigen supertype B44 by Cummings, Amy L, Gukasyan, Jaklin, Lu, Henry Y, Grogan, Tristan, Sunga, Gemalene, Fares, Charlene M, Hornstein, Nicholas, Zaretsky, Jesse, Carroll, James, Bachrach, Benjamin, Akingbemi, Wisdom O, Li, Debory, Noor, Zorawar, Lisberg, Aaron, Goldman, Jonathan W, Elashoff, David, Bui, Alex A T, Ribas, Antoni, Dubinett, Steven M, Rossetti, Maura, Garon, Edward B

“…Human leukocyte antigen (HLA)-B has been recognized as a major determinant of discrepancies in disease outcomes, and recent evidence indicates a role in immune…”
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