Search Results - "Sung-kyun Ko"

Zebrafish as a good vertebrate model for molecular imaging using fluorescent probes by Ko, Sung-Kyun, Chen, Xiaoqiang, Yoon, Juyoung, Shin, Injae

“…Fluorescent probes have been used extensively to monitor biomolecules and biologically relevant species in vitro and in vivo. A new trend in this area that has…”
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A thiol-specific fluorescent probe and its application for bioimaging by Chen, Xiaoqiang, Ko, Sung-Kyun, Kim, Min Jung, Shin, Injae, Yoon, Juyoung

“…A fluorescent probe based on fluorescein displays an excellent selectivity and sensitivity for thiols and its application for bioimaging is described…”
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An Autophagy‐Disrupting Small Molecule Promotes Cancer Cell Death via Caspase Activation by Park, Sang‐Hyun, Shin, Insu, Kim, Gun‐Hee, Ko, Sung‐Kyun, Shin, Injae

“…A novel autophagy inhibitor, autophazole (Atz), which promoted cancer cell death via caspase activation, is described. This compound was identified from…”
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New autophagy-modulating lanostane-type triterpenoids from a hallucinogenic poisonous mushroom Gymnopilus orientispectabilis by Lee, Seulah, Jang, Mina, Ryoo, Rhim, Roh, Jongtae, Ko, Sung-Kyun, Kim, Ki Hyun

“…Gymnopilus orientispectabilis , also known as “big laughter mushroom,” is a hallucinogenic poisonous mushroom that causes excessive laughter upon ingestion…”
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A chemodosimeter approach to fluorescent sensing and imaging of inorganic and methylmercury species by Santra, Mithun, Ryu, Dowook, Chatterjee, Amrita, Ko, Sung-Kyun, Shin, Injae, Ahn, Kyo Han

“…A highly sensitive fluorescent turn-on probe specific for methylmercury species as well as inorganic mercury ions has been developed on the basis of mercury…”
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Rhodamine-Based Cyclic Hydroxamate as Fluorescent pH Probe for Imaging of Lysosomes by Kim, Young Ju, Jang, Mina, Roh, Jongtae, Lee, Yoon Jeong, Moon, Hee Jung, Byun, Jimin, Wi, Jihyun, Ko, Sung-Kyun, Tae, Jinsung

“…Monitoring the microenvironment within specific cellular regions is crucial for a comprehensive understanding of life events. Fluorescent probes working in…”
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Xyloneside A: A New Glycosylated Incisterol Derivative from Xylaria sp. FB by Lee, Seoung Rak, Kreuzenbeck, Nina B., Jang, Mina, Oh, Taehoon, Ko, Sung‐Kyun, Ahn, Jong Seog, Beemelmanns, Christine, Kim, Ki Hyun

“…Xylaria species are prolific natural product producers. Here, we report the characterization of a new glycosylated incisterol derivative, called xyloneside A…”
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Genomics-Driven Discovery of Chlorinated Cyclic Hexapeptides Ulleungmycins A and B from a Streptomyces Species by Son, Sangkeun, Hong, Young-Soo, Jang, Mina, Heo, Kyung Taek, Lee, Byeongsan, Jang, Jun-Pil, Kim, Jong-Won, Ryoo, In-Ja, Kim, Won-Gon, Ko, Sung-Kyun, Kim, Bo Yeon, Jang, Jae-Hyuk, Ahn, Jong Seog

“…Analysis of the genome sequence of Streptomyces sp. KCB13F003 showed the presence of a cryptic gene cluster encoding flavin-dependent halogenase and…”
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A pipecolic acid-rich branched cyclic depsipeptide ulleungamide C from a Streptomyces species induces G0/G1 cell cycle arrest in promyelocytic leukemia cells by Son, Sangkeun, Jang, Mina, Lee, Byeongsan, Jang, Jun-Pil, Hong, Young-Soo, Kim, Bo Yeon, Ko, Sung-Kyun, Jang, Jae-Hyuk, Ahn, Jong Seog

“…In this study, screening by LC–MS and cytotoxicity-guided isolation led to the identification of ulleungamide C ( 1 ), a previously unknown pipecolic acid-rich…”
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Pentaminomycins A and B, Hydroxyarginine-Containing Cyclic Pentapeptides from Streptomyces sp. RK88-1441 by Jang, Jun-Pil, Hwang, Gwi Ja, Kwon, Min Cheol, Ryoo, In-Ja, Jang, Mina, Takahashi, Shunji, Ko, Sung-Kyun, Osada, Hiroyuki, Jang, Jae-Hyuk, Ahn, Jong Seog

“…Two new cyclic peptides, pentaminomycins A (1) and B (2), were isolated from cultures of Streptomyces sp. RK88-1441. Based on the interpretation of the NMR,…”
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In Vivo Monitoring of Mercury Ions Using a Rhodamine-Based Molecular Probe by Ko, Sung-Kyun, Yang, Young-Keun, Tae, Jinsung, Shin, Injae

“…Exposure to mercury causes severe damage to various tissues and organs in humans. Concern over mercury toxicity has encouraged the development of efficient,…”
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High-Contrast Reversible Fluorescence Photoswitching of Dye-Crosslinked Dendritic Nanoclusters in Living Vertebrates by Kim, Yoonkyung, Jung, Hye-youn, Choe, Yun Hui, Lee, Chaewoon, Ko, Sung-Kyun, Koun, Soonil, Choi, Yohan, Chung, Bong Hyun, Park, Byoung Chul, Huh, Tae-Lin, Shin, Injae, Kim, Eunkyoung

“…Dendrimers crosslinked with a photochromic diarylethene (blue in picture) were labeled with the fluorescent dye Cy3 (red) for reversible fluorescence…”
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Cardiosulfa Induces Heart Deformation in Zebrafish through the AhR-Mediated, CYP1A-Independent Pathway by Ko, Sung-Kyun, Shin, Injae

“…Heart development is a complicated and elaborate biological process. To study this and similar complicated process and diseases, the discovery and use of small…”
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Jejuketomycins A and B, polyketide glycosides with cancer cell migration inhibitory activity from Streptomyces sp. KCB15JA151 by Jang, Jun-Pil, Kim, Gil Soo, Oh, Tae Hoon, Park, Beomcheol, Kim, Minhee, Hwang, Gwi Ja, Lee, Hyeok-Won, Lee, Jin-Gyeom, Hong, Young-Soo, Ahn, Jong Seog, Ko, Sung-Kyun, Jang, Jae-Hyuk

“…Two new polyketide glycosides jejuketomycins A (1) and B (2), were isolated from a culture of Streptomyces sp. KCB15JA151. Their chemical structures including…”
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Isolation of new streptimidone derivatives, glutarimide antibiotics from Streptomyces sp. W3002 using LC-MS-guided screening by Lee, Byeongsan, Son, Sangkeun, Lee, Jae Kyoung, Jang, Mina, Heo, Kyung Taek, Ko, Sung-Kyun, Park, Dong-Jin, Park, Chan Sun, Kim, Chang-Jin, Ahn, Jong Seog, Hwang, Bang Yeon, Jang, Jae-Hyuk, Hong, Young-Soo

“…A LC-MS-guided screening led to the isolation of two new streptimidone derivatives ( 2 and 3 ) containing a glutarimide ring and two glutarimide ring-opened…”
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Mechanism of the natural product moracin-O derived MO-460 and its targeting protein hnRNPA2B1 on HIF-1α inhibition by Soung, Nak-Kyun, Kim, Hye-Min, Asami, Yukihiro, Kim, Dong Hyun, Cho, Yangrae, Naik, Ravi, Jang, Yerin, Jang, Kusic, Han, Ho Jin, Ganipisetti, Srinivas Rao, Cha-Molstad, Hyunjoo, Hwang, Joonsung, Lee, Kyung Ho, Ko, Sung-Kyun, Jang, Jae-Hyuk, Ryoo, In-Ja, Kwon, Yong Tae, Lee, Kyung Sang, Osada, Hiroyuki, Lee, Kyeong, Kim, Bo Yeon, Ahn, Jong Seog

“…Hypoxia-inducible factor-1α (HIF-1α) mediates tumor cell adaptation to hypoxic conditions and is a potentially important anticancer therapeutic target. We…”
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Catenulisporolides, Glycosylated Triene Macrolides from the Chemically Underexploited Actinomycete Catenulispora Species by Son, Sangkeun, Hong, Young-Soo, Futamura, Yushi, Jang, Mina, Lee, Jae Kyoung, Heo, Kyung Taek, Ko, Sung-Kyun, Lee, Jung Sook, Takahashi, Shunji, Osada, Hiroyuki, Jang, Jae-Hyuk, Ahn, Jong Seog

“…New glycosylated 26-membered triene macrolides catenulisporolides, the first polyketide metabolites from Catenulispora species, were obtained by targeting…”
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Highly oxygenated angucycline from Streptomyces sp. KCB15JA014 by Kim, Gil Soo, Kim, Geum Jin, Lee, Byeongsan, Oh, Tae Hoon, Kwon, Mincheol, Lee, Jung-Sook, Jang, Jun-Pil, Choi, Hyukjae, Ko, Sung-Kyun, Hong, Young-Soo, Jang, Jae-Hyuk, Ahn, Jong Seog

“…LC/MS-based chemical screening of culture extract led to a new highly oxygenated angucycline derivative, grecocycline D ( 1 ), from Streptomyces sp…”
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Inhibitory effects of flavonoids isolated from Sophora flavescens on indoleamine 2,3-dioxygenase 1 activity by Kwon, Mincheol, Ko, Sung-Kyun, Jang, Mina, Kim, Gun-Hee, Ryoo, In-Ja, Son, Sangkeun, Ryu, Hyung Won, Oh, Sei-Ryang, Lee, Won-Kyu, Kim, Bo Yeon, Jang, Jae-Hyuk, Ahn, Jong Seog

“…Indoleamine 2,3-dioxygenase 1 (IDO1), a tryptophan catabolising enzyme, is known as a tumour cell survival factor that causes immune escape in several types of…”
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Inhibitory effect of human indoleamine 2,3-dioxygenase 1 (hIDO1) by kazinols of 1,3-diphenylpropane derivatives by Oh, Taehoon, Jung, Sunin, Oh, Seon Min, Park, Mi Hyeon, Kim, Hyoung-Geun, Lee, Su-Yeon, Ko, Sung-Kyun, Ryu, Hyung Won

“…This study focused on identifying and characterizing 1,3-diphenylpropane derivatives from flavonoids that inhibit human indoleamine 2,3-dioxygenase 1 (hIDO1)…”
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