Search Results - "Sung, Yun Ju"
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Genomic atlas of the proteome from brain, CSF and plasma prioritizes proteins implicated in neurological disorders
Published in Nature neuroscience (01-09-2021)“…Understanding the tissue-specific genetic controls of protein levels is essential to uncover mechanisms of post-transcriptional gene regulation. In this study,…”
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Development and Applications of CRISPR/Cas9-Based Genome Editing in Lactobacillus
Published in International journal of molecular sciences (01-11-2022)“…Lactobacillus, a genus of lactic acid bacteria, plays a crucial function in food production preservation, and probiotics. It is particularly important to…”
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Nanoplasmonic immunosensor for the detection of SCG2, a candidate serum biomarker for the early diagnosis of neurodevelopmental disorder
Published in Scientific reports (23-11-2021)“…The neural circuits of the infant brain are rapidly established near 6 months of age, but neurodevelopmental disorders can be diagnosed only at the age of…”
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Biodegradation of Low Density Polyethylene by the Fungus Cladosporium sp. Recovered from a Landfill Site
Published in Journal of fungi (Basel) (24-05-2023)“…Low density polyethylene (LDPE) has been widely used commercially for decades; however, as a non-degradable material, its continuous accumulation has…”
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Novel antibody/gold nanoparticle/magnetic nanoparticle nanocomposites for immunomagnetic separation and rapid colorimetric detection of Staphylococcus aureus in milk
Published in Biosensors & bioelectronics (15-05-2013)“…We demonstrated the new antibody/gold nanoparticle/magnetic nanoparticle nanocomposites (antibody/AuNP/MNPs) and their application in the detection of the…”
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Genomic predictors of the maximal O2 uptake response to standardized exercise training programs
Published in Journal of applied physiology (1985) (01-05-2011)“…Low cardiorespiratory fitness is a powerful predictor of morbidity and cardiovascular mortality. In 473 sedentary adults, all whites, from 99 families of the…”
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Harmonization of CSF and imaging biomarkers in Alzheimer's disease: Need and practical applications for genetics studies and preclinical classification
Published in Neurobiology of disease (01-01-2024)“…In Alzheimer's disease (AD) research, cerebrospinal fluid (CSF) Amyloid beta (Aβ), Tau and pTau are the most accepted and well validated biomarkers. Several…”
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TOPMed imputed genomics enhances genomic atlas of the human proteome in brain, cerebrospinal fluid, and plasma
Published in Scientific data (16-04-2024)“…Comprehensive expression quantitative trait loci studies have been instrumental for understanding tissue-specific gene regulation and pinpointing functional…”
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Lacisediminimonas profundi gen. nov., sp. nov., a member of the family Oxalobacteraceae isolated from freshwater sediment
Published in Antonie van Leeuwenhoek (01-02-2020)“…A novel Gram-stain-negative bacterial strain, CHu64-6-4 T , was isolated from a 67-cm-long sediment core collected from the Daechung Reservoir at a water depth…”
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Lifestyle Risk Score: handling missingness of individual lifestyle components in meta-analysis of gene-by-lifestyle interactions
Published in European journal of human genetics : EJHG (01-05-2021)“…Recent studies consider lifestyle risk score (LRS), an aggregation of multiple lifestyle exposures, in identifying association of gene-lifestyle interaction…”
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Heritability of submaximal exercise heart rate response to exercise training is accounted for by nine SNPs
Published in Journal of applied physiology (1985) (01-03-2012)“…Endurance training-induced changes in hemodynamic traits are heritable. However, few genes associated with heart rate training responses have been identified…”
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Identifying blood pressure loci whose effects are modulated by multiple lifestyle exposures
Published in Genetic epidemiology (01-09-2020)“…Although multiple lifestyle exposures simultaneously impact blood pressure (BP) and cardiovascular health, most analysis so far has considered each single…”
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Emergence of oxacillin-resistant Staphylococcus lugdunensis carrying staphylococcal cassette chromosome mec type V in central Taiwan
Published in Journal of microbiology, immunology and infection (01-12-2016)“…Background Staphylococcus lugdunensis has emerged as a key pathogen for clinical infection. It is sensitive to most antistaphylococcal agents, but it is…”
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Methods for Collapsing Multiple Rare Variants in Whole-Genome Sequence Data
Published in Genetic epidemiology (01-09-2014)“…ABSTRACT Genetic Analysis Workshop 18 provided whole‐genome sequence data in a pedigree‐based sample and longitudinal phenotype data for hypertension and…”
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Genomic and transcriptomic predictors of triglyceride response to regular exercise
Published in British journal of sports medicine (01-12-2015)“…We performed genome-wide and transcriptome-wide profiling to identify genes and single nucleotide polymorphisms (SNPs) associated with the response of…”
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Plasma proteomics of SARS-CoV-2 infection and severity reveals impact on Alzheimer’s and coronary disease pathways
Published in iScience (21-04-2023)“…Identification of proteins dysregulated by COVID-19 infection is critically important for better understanding of its pathophysiology, building prognostic…”
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Performance of genotype imputations using data from the 1000 Genomes Project
Published in Human heredity (01-01-2012)“…Genotype imputations based on 1000 Genomes (1KG) Project data have the advantage of imputing many more SNPs than imputations based on HapMap data. It also…”
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The association of the vanin-1 N131S variant with blood pressure is mediated by endoplasmic reticulum-associated degradation and loss of function
Published in PLoS genetics (01-09-2014)“…High blood pressure (BP) is the most common cardiovascular risk factor worldwide and a major contributor to heart disease and stroke. We previously discovered…”
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PCSK9 variation and association with blood pressure in African Americans: preliminary findings from the HyperGEN and REGARDS studies
Published in Frontiers in genetics (08-04-2015)“…Proprotein convertase subtilisin/kexin type 9 (encoded by PCSK9) plays a well-known role in the regulation of low-density lipoprotein (LDL) receptors, and an…”
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