Search Results - "Sung, Uhna"
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Developing Fast Fluorescent Protein Voltage Sensors by Optimizing FRET Interactions
Published in PloS one (20-11-2015)“…FRET (Förster Resonance Energy Transfer)-based protein voltage sensors can be useful for monitoring neuronal activity in vivo because the ratio of signals…”
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Insertion of the voltage-sensitive domain into circularly permuted red fluorescent protein as a design for genetically encoded voltage sensor
Published in PloS one (01-09-2017)“…Visualization of electrical activity in living cells represents an important challenge in context of basic neurophysiological studies. Here we report a new…”
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3
Amphetamine induces a calcium/calmodulin-dependent protein kinase II-dependent reduction in norepinephrine transporter surface expression linked to changes in syntaxin 1A/transporter complexes
Published in Molecular pharmacology (01-01-2007)“…Norepinephrine (NE) transporters (NETs) are high-affinity transport proteins that mediate the synaptic clearance of NE after vesicular release. NETs represent…”
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4
Trafficking-dependent and -independent pathways of neurotransmitter transporter regulation differentially involving p38 mitogen-activated protein kinase revealed in studies of insulin modulation of norepinephrine transport in SK-N-SH cells
Published in The Journal of pharmacology and experimental therapeutics (01-11-2001)“…Presynaptic, cocaine- and antidepressant-sensitive norepinephrine (NE) transporters (NETs) dictate levels of extracellular NE after vesicular release. Recent…”
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5
Cell and Heparin Binding in the Distal Long Arm of Laminin: Identification of Active and Cryptic Sites with Recombinant and Hybrid Glycoprotein
Published in The Journal of cell biology (01-12-1993)“…The long arm of laminin, which binds heparin and cells, consists of three polypeptides (A, B1, and B2) joined in a coiled-coil rod attached to a terminal A…”
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6
Monitoring Brain Activity with Protein Voltage and Calcium Sensors
Published in Scientific reports (13-05-2015)“…Understanding the roles of different cell types in the behaviors generated by neural circuits requires protein indicators that report neural activity with high…”
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7
Recombinant laminin G domain mediates myoblast adhesion and heparin binding
Published in The Journal of biological chemistry (15-04-1993)“…A recombinant mouse cDNA fragment encoding the G domain of the basement membrane laminin A chain was inserted into the eukaryotic baculovirus expression vector…”
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Ca2+ dependent surface trafficking of norepinephrine transporters depends on threonine 30 and Ca2+ calmodulin kinases
Published in Journal of chemical neuroanatomy (01-10-2017)“…•Ca2+ signaling influences NE clearance. Changes of external Ca2+ and neuronal depolarization increase surface NET proteins.•Mutagenesis of Thr30 and…”
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9
Improving Signal Dynamics of Fluorescent Protein Voltage Sensors by Optimizing FRET Interactions
Published in Biophysical journal (27-01-2015)Get full text
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10
Development of Novel FRET-Based Fluorescent Voltage Sensor Proteins
Published in Biophysical journal (27-01-2015)Get full text
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11
Ca 2+ dependent surface trafficking of norepinephrine transporters depends on threonine 30 and Ca 2+ calmodulin kinases
Published in Journal of chemical neuroanatomy (01-10-2017)“…The antidepressant-sensitive norepinephrine (NE) transporter (NET) inactivates NE released during central and peripheral neuronal activity by transport into…”
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12
In Vivo Imaging of Odor-Evoked Responses in the Mouse Olfactory Bulb Using the FP Voltage Sensor ArcLight and the Calcium Sensor GCaMP3
Published in Biophysical journal (28-01-2014)Get full text
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13
Nabi, a Novel FRET-Based Voltage Sensor Protein
Published in Biophysical journal (28-01-2014)Get full text
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14
Genetically Encoded Protein Sensors of Membrane Potential
Published in Advances in experimental medicine and biology (2015)“…Organic voltage-sensitive dyes offer very high spatial and temporal resolution for imaging neuronal function. However these dyes suffer from the drawbacks of…”
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In Vivo Imaging of Odor-Evoked Responses in the Olfactory Bulb using Arclight, a Novel Fp Voltage Probe
Published in Biophysical journal (29-01-2013)Get full text
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16
Development of New Fluorescent Voltage Sensor Proteins
Published in Biophysical journal (29-01-2013)Get full text
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17
Imaging Membrane Potential with Two Types of Genetically Encoded Fluorescent Voltage Sensors
Published in Journal of visualized experiments (04-02-2016)Get full text
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Imaging Membrane Potential with Two Types of Genetically Encoded Fluorescent Voltage Sensors
Published in Journal of visualized experiments (04-02-2016)“…Genetically encoded voltage indicators (GEVIs) have improved to the point where they are beginning to be useful for in vivo recordings. While the ultimate goal…”
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A Regulated Interaction of Syntaxin 1A with the Antidepressant-Sensitive Norepinephrine Transporter Establishes Catecholamine Clearance Capacity
Published in The Journal of neuroscience (01-03-2003)“…Norepinephrine (NE) transporters (NETs) terminate noradrenergic synaptic transmission and represent a major therapeutic target for antidepressant medications…”
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20
Calcium-dependent interactions of the human norepinephrine transporter with syntaxin 1A
Published in Molecular and cellular neuroscience (01-02-2007)“…The norepinephrine (NE) transporter (NET) terminates noradrenergic signaling by clearing released NE at synapses. The activity of NET can be rapidly regulated…”
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