Search Results - "Sung, Fion"

Hyperhomocysteinemia Activates Nuclear Factor-κB in Endothelial Cells via Oxidative Stress by Au-Yeung, Kathy K.W, Woo, Connie W.H, Sung, Fion L, Yip, Johnny C.W, Siow, Yaw L, O, Karmin

“…ABSTRACT—Hyperhomocysteinemia is an independent risk factor for cardiovascular diseases. Our previous studies demonstrated an important interaction between…”
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The preclinical activity of the histone deacetylase inhibitor PXD101 (belinostat) in hepatocellular carcinoma cell lines by Ma, Brigette B.Y., Sung, Fion, Tao, Qian, Poon, Fan Fong, Lui, Vivian W., Yeo, Winnie, Chan, Stephen L., Chan, Anthony T.C.

“…Summary The activity of the histone deacetylase inhibitor PXD101 was investigated in three hepatocellular carcinoma (HCC) cell lines. PXD101was found to…”
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Plasma Osteopontin, Hypoxia, and Response to Radiotherapy in Nasopharyngeal Cancer by HUI, Edwin P, SUNG, Fion L, YU, Brian K. H, WONG, Cesar S. C, MA, Brigette B. Y, XIAORONG LIN, CHAN, Andrew, WONG, Wai-Lap, CHAN, Anthony T. C

“…Purpose: Recent studies have suggested that osteopontin is induced by hypoxia in head and neck cancer cell lines and its plasma level may serve as a surrogate…”
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Increased Monocyte Adhesion to Aortic Endothelium in Rats With Hyperhomocysteinemia: Role of Chemokine and Adhesion Molecules by Wang, Guoping, Woo, Connie W.H, Sung, Fion L, Siow, Yaw L, O, Karmin

“…OBJECTIVE—The stimulatory effect of homocysteine (Hcy) on monocyte chemoattractant protein (MCP)-1 expression in vitro has been suggested to play an important…”
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Silencing of hypoxia-inducible tumor suppressor lysyl oxidase gene by promoter methylation activates carbonic anhydrase IX in nasopharyngeal carcinoma by Sung, Fion L, Cui, Yan, Hui, Edwin P, Li, Lili, Loh, Thomas Ks, Tao, Qian, Chan, Anthony Tc

“…Lysyl oxidase (LOX) is an oxidative enzyme known to initiate the cross-linking of collagens and elastin, and suggested recently as a tumor suppressor for…”
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Genome-wide expression analysis using microarray identified complex signaling pathways modulated by hypoxia in nasopharyngeal carcinoma by Sung, Fion L, Hui, Edwin P, Tao, Qian, Li, Hongyu, Tsui, Nancy B.Y, Dennis Lo, Y.M, Ma, Brigette B.Y, To, Ka F, Harris, Adrian L, Chan, Anthony T.C

“…Abstract Previously, we showed that hypoxia-inducible factor (HIF)-1α, HIF-2α, carbonic anhydrase IX (CA IX), and vascular endothelial growth factor (VEGF)…”
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Hypoxia-targeting by tirapazamine (TPZ) induces preferential growth inhibition of nasopharyngeal carcinoma cells with Chk1/2 activation by Hong, Bo, Lui, Vivian W. Y., Hui, Edwin P., Ng, Margaret H. L., Cheng, Suk-Hang, Sung, Fion L., Tsang, Chi-Man, Tsao, Sai-Wah, Chan, Anthony Tak-Cheung

“…Summary Hypoxia is commonly developed in solid tumors, which contributes to metastasis as well as radio- and chemo-resistance. Nasopharyngeal carcinoma (NPC)…”
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Pharmacoproteomics Study of Cetuximab in Nasopharyngeal Carcinoma by Sung, Fion L, Pang, Ronald T. K, Ma, Brigette B. Y, Lee, May M. L, Chow, Shuk Man, Poon, Terence C. W, Chan, Anthony T. C

“…Epidermal growth factor receptor (EGFR) is usually overexpressed in nasopharyngeal carcinoma (NPC). Our recent in vitro study has demonstrated that cetuximab…”
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Effect of magnesium tanshinoate B on the production of nitric oxide in endothelial cells by O, K, Cheung, F, Sung, F L, Zhu, D Y, Siow, Y L

“…Nitric oxide (NO) is a potent vasodilator which plays an important role in regulating vascular tones. Danshen, a Chinese herbal medicine has been widely used…”
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Antitumor Effect and Enhancement of Cytotoxic Drug Activity by Cetuximab in Nasopharyngeal Carcinoma Cells by Sung, Fion Lan, Poon, Terence Cheun Wai, Hui, Edwin Pun, Ma, Brigette Buig Yue, Liong, Eleanore, To, Ka Fai, Huang, Dolly Poon Wai Sin, Chan, Anthony Tak Cheung

“…Background: Nasopharyngeal carcinoma (NPC) is the most common head and neck cancer in southern China and South East Asia. Epidermal growth factor receptor…”
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Homocysteine stimulates the expression of monocyte chemoattractant protein-1 in endothelial cells leading to enhanced monocyte chemotaxis by Sung, F L, Slow, Y L, Wang, G, Lynn, E G, O, K

“…Hyperhomocysteinemia has been identified as an independent risk factor for atherosclerosis. The infiltration of monocytes into the arterial wall is one of the…”
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Enhanced MCP-1 expression during ischemia/reperfusion injury is mediated by oxidative stress and NF- B by Sung, Fion L, Zhu, Tong Y, Au-Yeung, Kathy K W, Siow, Yaw L, Karmin, O

“…Renal ischemia/reperfusion injury is a major cause of acute renal failure in both native kidneys and renal allografts. One important feature of such injury is…”
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Enhanced MCP-1 expression during ischemia/reperfusion injury is mediated by oxidative stress and NF-κB by Sung, Fion L., Zhu, Tong Y., Au-Yeung, Kathy K.W., Siow, Yaw L., Karmin, O.

“…Enhanced MCP-1 expression during ischemia/reperfusion injury is mediated by oxidative stress and NF-κB. Renal ischemia/reperfusion injury is a major cause of…”
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Enhanced MCP-1 expression during ischemia/reperfusion injury is mediated by oxidative stress and NF-kappaB by Sung, Fion L, Zhu, Tong Y, Au-Yeung, Kathy K W, Siow, Yaw L, O, Karmin

“…Renal ischemia/reperfusion injury is a major cause of acute renal failure in both native kidneys and renal allografts. One important feature of such injury is…”
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Hyperhomocysteinemia activates nuclear factor-kappaB in endothelial cells via oxidative stress by Au-Yeung, Kathy K W, Woo, Connie W H, Sung, Fion L, Yip, Johnny C W, Siow, Yaw L, O, Karmin

“…Hyperhomocysteinemia is an independent risk factor for cardiovascular diseases. Our previous studies demonstrated an important interaction between nuclear…”
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Enhanced MCP-1 expression during ischemia/reperfusion injury is mediated by oxidative stress and NF-KB by SUNG, Fion L, ZHU, Tong Y, AU-YEUNG, Kathy K. W, SIOW, Y. A. W. L, O, Karmin

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