Search Results - "Sundler, Roger"

The role of lipid rafts in LPS-induced signaling in a macrophage cell line by Olsson, Sandra, Sundler, Roger

“…The significance of lipid rafts in lipopolysaccharide (LPS) signaling in macrophages was studied through isolation of them by gradient centrifugation and…”
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Different roles for non-receptor tyrosine kinases in arachidonate release induced by zymosan and Staphylococcus aureus in macrophages by Olsson, Sandra, Sundler, Roger

“…Yeast and bacteria elicit arachidonate release in macrophages, leading to the formation of leukotrienes and prostaglandins, important mediators of…”
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Regulation of phospholipase C-γ2 via phosphatidylinositol 3-kinase in macrophages by Hiller, Gösta, Sundler, Roger

“…Phospholipase C-γ (PLC-γ) isoforms are thought to be activated by both tyrosine phosphorylation and phosphatidylinositol 3,4,5 trisphosphate (PtdIns 3,4,5 P…”
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Signaling to localized degranulation in neutrophils adherent to immune complexes by Nauclér, Claes, Grinstein, Sergio, Sundler, Roger, Tapper, Hans

“…The present study demonstrates that the secretion of azurophilic granules occurring during Fc receptor‐mediated attachment and spreading of neutrophils is…”
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Bafilomycin A1 inhibits lysosomal, phagosomal, and plasma membrane H(+)-ATPase and induces lysosomal enzyme secretion in macrophages by Tapper, H, Sundler, R

“…Bafilomycin A1, a specific inhibitor of H(+)-ATPases of the vacuolar type, was in the present study shown, at similar concentrations, to induce secretion of…”
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A phospholipase A2 hydrolyzing arachidonoyl‐phospholipids in mouse peritonea macrophages by Wijkander, Jonny, Sundler, Roger

“…A calcium‐dependent phospholipase A2 with half‐maximal activity at approx. 0.7 μM free Ca2+ has been identified in the cytosolic fraction from macrophages. The…”
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The macrophage β-glucan receptor mediates arachidonate release induced by zymosan: Essential role for Src family kinases by Olsson, Sandra, Sundler, Roger

“…Yeast-derived zymosan beads are among the classical agents used to induce sterile inflammatory responses in experimental animals and macrophage activation in…”
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Protein kinase C and intracellular pH regulate zymosan-induced lysosomal enzyme secretion in macrophages by Tapper, H, Sundler, R

“…Binding of zymosan particles to macrophage beta-glucan receptors has previously been shown to trigger exocytosis of preformed lysosomal contents. In the…”
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Dexamethasone Differentially Regulates Cytokine Transcription and Translation in Macrophages Responding to Bacteria or Okadaic Acid by Gewert, Karin, Svensson, Ulf, Andersson, Karolina, Holst, Elisabet, Sundler, Roger

“…Many microorganisms and microbial products induce expression of pro-inflammatory cytokines such as interleukin-1 (IL-1α/β) and tumour necrosis factor-α (TNF-α)…”
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Promotion of acid-induced membrane fusion by basic peptides. Amino acid and phospholipid specificities by Bondeson, J, Sundler, R

“…The ability of oligo- and polymers of the basic amino acids L-lysine, L-arginine, L-histidine and L-ornithine to induce lipid intermixing and membrane fusion…”
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Posttranscriptional regulation of TNFα expression via eukaryotic initiation factor 4E (eIF4E) phosphorylation in mouse macrophages by Andersson, Karolina, Sundler, Roger

“…Resident mouse macrophages secrete Tumor necrosis factor α (TNFα) upon challenge with LPS. The production of TNFα is controlled not only at the transcription…”
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Studies on the effective size of phospholipid headgroups in bilayer vesicles using lectin-glycolipid interaction as a steric probe by Sundler, R

“…An experimental approach is described which provides information about the relative, effective size of phospholipid headgroups in bilayer vesicles. It is based…”
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Posttranscriptional regulation of TNFalpha expression via eukaryotic initiation factor 4E (eIF4E) phosphorylation in mouse macrophages by Andersson, Karolina, Sundler, Roger

“…Resident mouse macrophages secrete Tumor necrosis factor alpha (TNFalpha) upon challenge with LPS. The production of TNFalpha is controlled not only at the…”
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Regulation of selenoprotein mRNA expression by hormones and retinoic acid in bovine mammary cells by Bruzelius, Katharina, Sundler, Roger, Pagmantidis, Vasileios, Åkesson, Björn

“…Selenium is essential for maintaining many body functions through the actions of selenoproteins. To find factors regulating selenoprotein biosynthesis in the…”
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Effect of Different Fatty Acids on Glycerolipid Synthesis in Isolated Rat Hepatocytes by Sundler, Roger, Åkesson, Björn, Nilsson, Åke

“…Glycerolipid synthesis from [3H]glycerol and [14C]dihydroxyacetone operated in enzymically isolated rat hepatocytes at a rate similar to that in the intact…”
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Occurrence of selenoprotein enzyme activities and mRNA in bovine mammary tissue by Bruzelius, K, Hoac, T, Sundler, R, Onning, G, Akesson, B

“…To elucidate the possible role of selenoproteins for milk formation and mammary gland physiology, the activities of selenoprotein enzymes and the expression of…”
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Activation of arachidonate release and cytosolic phospholipase A2 via extracellular signal-regulated kinase and p38 mitogen-activated protein kinase in macrophages stimulated by bacteria or zymosan by Hiller, G, Sundler, R

“…The mitogen-activated protein kinases (MAP kinases), extracellular signal-regulated kinase (ERK) and p38, can both contribute to the activation of cytosolic…”
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Regulation of phospholipase C-gamma 2 via phosphatidylinositol 3-kinase in macrophages by Hiller, Gösta, Sundler, Roger

“…Phospholipase C-gamma (PLC-gamma) isoforms are thought to be activated by both tyrosine phosphorylation and phosphatidylinositol 3,4,5 trisphosphate (PtdIns…”
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Phosphatidylinositol-4-phosphate kinase from rat brain. Activation by polyamines and inhibition by phosphatidylinositol 4,5-bisphosphate by Lundberg, G A, Jergil, B, Sundler, R

“…Phosphatidylinositol-4-phosphate (PtdIns-P) kinase was purified approximately 30-fold from rat brain cytosol. No contaminating activity of PtdIns kinase or of…”
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SIGNALLING TO TRANSLATIONAL ACTIVATION OF TUMOUR NECROSIS FACTOR-α EXPRESSION IN HUMAN THP-1 CELLS by Andersson, Karolina, Sundler, Roger

“…Monocytic THP-1 cells expressed tumour necrosis factor-α (TNF-α) mRNA, but hardly any detectable TNF-α protein and a partially activated MAP kinase ERK-2 in…”
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