Search Results - "Sundick, R"

A cloned chicken lymphokine homologous to both mammalian IL-2 and IL-15 by Sundick, RS, Gill-Dixon, C

“…IL-2, cloned in several mammalian species, plays a critical role in immune system function. Indirect evidence suggests that IL-2-like molecules also exist in…”
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A recombinant turkey herpesvirus expressing chicken interleukin-2 increases the protection provided by in ovo vaccination with infectious bursal disease and infectious bronchitis virus by Tarpey, I, van Loon, A.A, de Haas, N, Davis, P.J, Orbell, S, Cavanagh, D, Britton, P, Casais, R, Sondermeijer, P, Sundick, R

“…Abstract In ovo vaccination remains an attractive option for the mass application of vaccines to poultry, ensuring a uniform application of vaccine in a…”
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Thyroid cell injury is an initial event in the induction of autoimmune thyroiditis by iodine in obese strain chickens by Bagchi, N, Brown, T R, Sundick, R S

“…The present study examines the role of thyroid cell injury in the initiation of autoimmune thyroiditis by iodine in Obese strain (OS) chickens, a strain…”
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Expression of chicken interleukin-2 by turkey herpesvirus increases the immune response against Marek's disease virus but fails to increase protection against virulent challenge by Tarpey, I, Davis, P.J, Sondermeijer, P, Geffen, C. van, Verstegen, I, Schijns, V.E.J.C, Kolodsick, J, Sundick, R

“…As Marek's disease virus continues to evolve towards greater virulence, more efficacious vaccines will be required in the future. We expressed chicken…”
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Induction of autoimmune thyroiditis in chickens by dietary iodine by Bagchi, N, Brown, T.R, Urdanivia, E, Sundick, R.S

“…Clinical studies have suggested that excess dietary iodine promotes autoimmune thyroiditis; however, the lack of a suitable animal model has hampered…”
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Identification of a G protein coupled receptor induced in activated T cells by Kaplan, MH, Smith, DI, Sundick, RS

“…Many genes are induced after T cell activation to make a cell competent for proliferation and ultimately, function. Many of these genes encode surface…”
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Alternate forms of MHC class II-associated invariant chain are not produced by alternative splicing in rainbow trout ( Oncorhynchus mykiss) but are encoded by separate genes by Fujiki, Kazuhiro, Smith, Cortney M., Liu, Lei, Sundick, Roy S., Dixon, Brian

“…A major limiting factor in understanding teleost major histocompatibility receptor function is the lack of knowledge about antigen presentation accessory…”
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The role of iodine in thyroid autoimmunity: from chickens to humans: a review by Sundick, R S, Bagchi, N, Brown, T R

“…Evidence has been presented to support the idea that iodine plays an important role in autoimmune thyroiditis. Excessive amounts induce thyroiditis in…”
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Uptake and metabolism of iodine is crucial for the development of thyroiditis in obese strain chickens by BROWN, T. R, SUNDICK, R. S, DHAR, A, SHETH, D, BAGCHI, N

“…To assess the importance of the role of thyroidal iodine in the pathogenesis of thyroiditis in the obese strain (OS) chicken, a model of spontaneous and severe…”
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Distinct regions of thyroglobulin control the proliferation and suppression of thyroid-specific lymphocytes in obese strain chickens by Bagchi, N, Sundick, R S, Hu, L H, Cummings, G D, Brown, T R

“…The effect of thyroglobulin (Tg)iodination on the proliferation and suppression of thyroid-specific lymphocytes was examined in vivo in the obese strain (OS)…”
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The obese strain chicken as a model for human Hashimoto's thyroiditis by Sundick, R S, Bagchi, N, Brown, T R

“…The OS and the related Cornell C strain are interesting animal models for the study of the etiology of autoimmune thyroiditis. They are especially valuable for…”
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Molecular cloning and characterization of rainbow trout (Oncorhynchus mykiss) C5a anaphylatoxin receptor by Fujiki, Kazuhiro, Liu, Lei, Sundick, Roy S, Dixon, Brian

“…In the course of suppression subtractive hybridization between the cDNA of phytohemagglutinin-stimulated and non-stimulated head kidney cells in rainbow trout…”
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Thyroid injury, autoantigen availability, and the initiation of autoimmune thyroiditis by BROWN, T. R, GUANHAU ZHAO, PALMER, K. C, SUNDICK, R. S

“…Iodine depletion prevents disease and iodine repletion, which may cause thyroid cell injury by reactive oxygen intermediates, initiates disease in the Obese…”
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The incorporation of dietary iodine into thyroglobulin increases its immunogenicity by Sundick, R S, Herdegen, D M, Brown, T R, Bagchi, N

“…Experiments were performed to analyze one mechanism by which elevated levels of dietary iodine may induce thyroglobulin (Tg) autoantibodies. We tested the…”
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Production and in vitro characterization of recombinant chicken interleukin-2 by Stepaniak, J A, Shuster, J E, Hu, W, Sundick, R S

“…Mammalian interleukin-2 (IL-2) is a well-characterized cytokine that plays key roles in T cell differentiation and activation, B cell development, and natural…”
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Antioxidants delay the onset of thyroiditis in obese strain chickens by Bagchi, N, Brown, T R, Herdegen, D M, Dhar, A, Sundick, R S

“…Dietary iodine has been shown to be important in the induction of thyroiditis in susceptible chicken strains although the underlying mechanism remains unknown…”
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MUTATIONAL ANALYSIS OF CHICKEN INTERLEUKIN 2 by Kolodsick, Jill E., Stepaniak, Jolie A., Hu, Wanping, Sundick, Roy S.

“…Chicken interleukin 2 (chIL-2) has low, but significant, homology to both mammalian IL-2 and mammalian IL-15. In view of its unique phylogenetic position and…”
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Enhanced response to Con A and production of TCGF by lymphocytes of obese strain (OS) chickens with spontaneous autoimmune thyroiditis by Schauenstein, K, Kromer, G, Sundick, RS, Wick, G

“…The mitogenic response to Con A and the production of T cell growth factor or interleukin 2 (IL 2) by splenic and peripheral blood lymphocytes of obese strain…”
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Thyroidal iodine metabolism in obese-strain chickens before immune-mediated damage by Sundick, R S, Herdegen, D, Brown, T R, Dhar, A, Bagchi, N

“…Several studies have shown that iodine plays a role in spontaneous autoimmune thyroiditis in man and other animals. In addition, abnormalities of iodine…”
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Analysis of lymphocytes infiltrating the thyroid gland of Obese strain chickens by Kromer, G, Sundick, RS, Schauenstein, K, Hala, K, Wick, G

“…Lymphocytes were isolated from the infiltrated thyroid glands of 2- to 5-wk-old Obese strain (OS) chickens with spontaneous autoimmune thyroiditis (SAT)…”
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