Search Results - "Sundh, Daniel"
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Grade 1 Vertebral Fractures Identified by Densitometric Lateral Spine Imaging Predict Incident Major Osteoporotic Fracture Independently of Clinical Risk Factors and Bone Mineral Density in Older Women
Published in Journal of bone and mineral research (01-10-2020)“…ABSTRACT Because prevalent vertebral fracture (VF) is a strong predictor of future fractures, they are important to identify in clinical practice as…”
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Cortical and trabecular bone microarchitecture as an independent predictor of incident fracture risk in older women and men in the Bone Microarchitecture International Consortium (BoMIC): a prospective study
Published in The lancet. Diabetes & endocrinology (01-01-2019)“…Although areal bone mineral density (aBMD) assessed by dual-energy x-ray absorptiometry (DXA) is the clinical standard for determining fracture risk, most…”
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High‐Impact Mechanical Loading Increases Bone Material Strength in Postmenopausal Women—A 3‐Month Intervention Study
Published in Journal of bone and mineral research (01-07-2018)“…ABSTRACT Bone adapts to loading in several ways, including redistributing bone mass and altered geometry and microarchitecture. Because of previous…”
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One-year supplementation with Lactobacillus reuteri ATCC PTA 6475 counteracts a degradation of gut microbiota in older women with low bone mineral density
Published in NPJ biofilms and microbiomes (19-10-2022)“…Recent studies have shown that probiotic supplementation has beneficial effects on bone metabolism. In a randomized controlled trial (RCT) we demonstrated that…”
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Intermediate monocytes correlate with CXCR3+ Th17 cells but not with bone characteristics in untreated early rheumatoid arthritis
Published in PloS one (2021)“…Rheumatoid arthritis (RA) is associated with development of generalized osteoporosis. Bone-degrading osteoclasts are derived from circulating precursor cells…”
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Metabolic Alterations in Older Women With Low Bone Mineral Density Supplemented With Lactobacillus reuteri
Published in JBMR plus (01-04-2021)“…ABSTRACT Osteoporosis and its associated fractures are highly prevalent in older women. Recent studies have shown that gut microbiota play important roles in…”
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Synergy and oxygen adaptation for development of next-generation probiotics
Published in Nature (London) (10-08-2023)“…The human gut microbiota has gained interest as an environmental factor that may contribute to health or disease 1 . The development of next-generation…”
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Lactobacillus reuteri reduces bone loss in older women with low bone mineral density: a randomized, placebo‐controlled, double‐blind, clinical trial
Published in Journal of internal medicine (01-09-2018)“…Background The importance of the gut microbiome for bone metabolism in mice has recently been demonstrated, but no studies are available in humans…”
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Current Physical Activity Is Independently Associated With Cortical Bone Size and Bone Strength in Elderly Swedish Women
Published in Journal of bone and mineral research (01-03-2017)“…ABSTRACT Physical activity is believed to have the greatest effect on the skeleton if exerted early in life, but whether or not possible benefits of physical…”
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Increased Cortical Porosity in Older Men With Fracture
Published in Journal of bone and mineral research (01-09-2015)“…ABSTRACT Cortical porosity increases with age and affects bone strength, but its association with fracture in older men is unknown. The aim of this study was…”
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Cortical bone area predicts incident fractures independently of areal bone mineral density in older men
Published in The journal of clinical endocrinology and metabolism (01-02-2017)“…Context:Areal bone mineral density (aBMD) measured using dual-energy X-ray absorptiometry (DXA) is used clinically to predict fracture but does not allow…”
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Type 2 Diabetes Mellitus Is Associated With Better Bone Microarchitecture But Lower Bone Material Strength and Poorer Physical Function in Elderly Women: A Population‐Based Study
Published in Journal of bone and mineral research (01-05-2017)“…ABSTRACT Type 2 diabetes mellitus (T2DM) is associated with an increased risk of fractures according to several studies. The underlying mechanisms remain…”
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A High Amount of Local Adipose Tissue Is Associated With High Cortical Porosity and Low Bone Material Strength in Older Women
Published in Journal of bone and mineral research (01-04-2016)“…ABSTRACT Obesity is associated with increased risk of fractures, especially at skeletal sites with a large proportion of cortical bone, such as the humerus and…”
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Vertebral fractures and their association with health-related quality of life, back pain and physical function in older women
Published in Osteoporosis international (01-01-2018)“…Summary Studies investigating prevalent vertebral fracture (VF) diagnosed using densitometry-based VF assessment (VFA) and associations with physical function,…”
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Increased Bone Material Strength Index Is Positively Associated With the Risk of Incident Osteoporotic Fractures in Older Swedish Women
Published in Journal of bone and mineral research (01-06-2023)“…ABSTRACT No previous studies have investigated the association between the bone material strength index (BMSi; an indicator of bone material properties…”
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High-Impact Mechanical Loading Increases Bone Material Strength in Postmenopausal WomenA 3-Month Intervention Study
Published in Journal of bone and mineral research (01-07-2018)“…Bone adapts to loading in several ways, including redistributing bone mass and altered geometry and microarchitecture. Because of previous methodological…”
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Extensive undertreatment of osteoporosis in older Swedish women
Published in Osteoporosis international (01-06-2019)“…Summary In a population-based study of older Swedish women, we investigated the proportion of women treated with osteoporosis medication in relation to the…”
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Low-level cadmium exposure is associated with decreased cortical thickness, cortical area and trabecular bone volume fraction in elderly men: The MrOS Sweden study
Published in Bone (New York, N.Y.) (01-02-2021)“…It is well known that high-level exposure to cadmium can cause bone disease such as osteoporosis, osteomalacia and fractures. However, the effect of low-level…”
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Because prevalent vertebral fracture (VF) is a strong predictor of future fractures, they are important to identify in clinical practice as osteoporosis medications are effective and can be used to reduce fracture risk in postmenopausal women with VF. Lateral spine imaging (LSI) with dual-energy X-ray absorptiometry (DXA) can be used to diagnose VFs accurately but is not widespread in clinical practice. The prognostic value of grade 1 (20% to 25% compression) VFs diagnosed by LSI with DXA has be
Published in Journal of bone and mineral research (2020)“…Because prevalent vertebral fracture (VF) is a strong predictor of future fractures, they are important to identify in clinical practice as osteoporosis…”
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Journal Article