Search Results - "Sundermann, K."
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Reconstructing tumor evolutionary histories and clone trees in polynomial-time with SubMARine
Published in PLoS computational biology (19-01-2021)“…Tumors contain multiple subpopulations of genetically distinct cancer cells. Reconstructing their evolutionary history can improve our understanding of how…”
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Haemodialysis is associated with changes in cutaneous microcirculation in diabetes mellitus
Published in Diabetic medicine (01-01-2009)“…Aims To examine the cutaneous microcirculation on the dorsum of the foot before, during and after haemodialysis in diabetic and non‐diabetic patients. Methods…”
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Total Synthesis of Epothilone B, Epothilone D, and cis- and trans-9,10-Dehydroepothilone D
Published in Journal of the American Chemical Society (13-06-2001)“…The phosphonium salt 35, representing one of the two principal subunits of the epothilones, was prepared from propargyl alcohol via heptenone 22. A Wittig…”
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The “Hydrogen-Subway”A Tunneling Approach to Intramolecular Hydrogen Transfer Reactions Controlled by Ultrashort Laser Pulses
Published in The journal of physical chemistry. A, Molecules, spectroscopy, kinetics, environment, & general theory (19-11-1998)“…Isomerization reactions from a reactant state to a near-degenerate product state which are typical for intramolecular hydrogen transfer may be achieved by…”
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Does autonomic blockade reveal a potent contribution of nitric oxide to locomotion-induced vasodilation?
Published in American journal of physiology. Heart and circulatory physiology (01-08-2000)“…We sought to test the role of nitric oxide (NO) in governing skeletal muscle (iliac) vascular conductance during treadmill locomotion in dogs (n = 6; 3.2 and…”
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Laser driven hydrogen tunneling in a dissipative environment
Published in Chemical physics (1999)“…The recently proposed tunneling approach (N. Došlić, O. Kühn, J. Manz, K. Sundermann, J. Phys. Chem. A, in press) by which isomerization reactions can be…”
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Design and interpretation of laser pulses for the control of quantum systems
Published in Applied physics. B, Lasers and optics (01-09-2000)“…An extended theory of optimal control strategies for the design of feasible laser pulses is presented. The theoretical framework includes the control of…”
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Ab initio three-dimensional quantum dynamics of Ag 3 clusters in the NeNePo process
Published in Chemical physics letters (18-02-2000)“…The first three-dimensional quantum-dynamical ab initio simulation of the large amplitude vibrational dynamics of an Ag 3 cluster initiated from its linear…”
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Improved Synthesis of Epothilone B Employing Alkylation of an Alkyne for Assembly of Subunits
Published in Organic letters (04-11-1999)“…A strategy for assembling the two principal modules of epothilone B was developed that merges an allylic bromide with a terminal acetylene to fabricate the…”
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Cytotoxic Hypothemycin Analogues from Hypomyces subiculosus
Published in Journal of natural products (Washington, D.C.) (01-10-2006)“…Three new hypothemycin analogues were isolated from the fungal strains Hypomyces subiculosus DSM 11931 and DSM 11932. The structures of these compounds were…”
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Quantum optimal control strategies for photoisomerization via electronically excited states
Published in Chemical physics letters (1998)“…Optimal control of the photoisomerization of Li 2Na from the stable acute to the near-degenerate obtuse triangular configuration is simulated by means of…”
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Rapid access to epothilone analogs via semisynthetic degradation and reconstruction of epothilone D
Published in Tetrahedron letters (23-02-2004)“…Graphic A facile and efficient route to epothilone analogs has been developed from the natural product epothilone D ( 1 ). Degradation of 1 via an oxidative…”
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Ab initio three-dimensional quantum dynamics of Ag3 clusters in the NeNePo process
Published in Chemical physics letters (01-02-2000)Get full text
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Toward Understanding How the Lactone Moiety of Discodermolide Affects Activity
Published in Journal of the American Chemical Society (11-05-2005)“…A series of simplified discodermolide analogues have been designed and synthesized in an attempt to understand the role of the lactone ring. These synthetic…”
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Design, Synthesis, and Evaluation of Carbamate-Substituted Analogues of (+)-Discodermolide
Published in Organic letters (20-01-2005)“…The design, syntheses, and biological evaluation of 22 totally synthetic analogues of the potent microtubule-stabilizing agent (+)-discodermolide (1) have been…”
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A Highly Stereoselective Synthesis of Epothilone B
Published in Journal of organic chemistry (05-02-1999)Get full text
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Design, Synthesis, and Evaluation of Analogues of (+)-14-Normethyldiscodermolide
Published in Organic letters (20-01-2005)“…The design, syntheses, and biological evaluation of nine totally synthetic analogues of the microtubule-stabilizing agent (+)-14-normethyldiscodermolide (2)…”
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TA-Net NRW
Published in TATuP - Zeitschrift für Technikfolgenabschätzung in Theorie und Praxis (01-03-2000)Get full text
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A series of 23,24-dihydrodiscodermolide analogues with simplified lactone regions
Published in Bioorganic & medicinal chemistry letters (01-04-2006)“…A collection of seven new 23,24-dihydrodiscodermolide analogues have been synthesized with modifications to the lactone ring, some of which show…”
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