Search Results - "Sundar, P Shyam"
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Identification of (2,3)-2-(3,4-dihydroxyphenyl)chroman-3-yl-3,4,5-trihydroxy benzoate as multiple inhibitors of SARS-CoV-2 targets; a systematic molecular modelling approach
Published in RSC advances (07-04-2021)“…Coronavirus disease of 2019 (COVID-19) is a zoonotic disease caused by a new severe acute respiratory syndrome (SARS-CoV-2) which has quickly resulted in a…”
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Distinct Modulation of Wild-Type and Selective Gene Mutated Vitamin D Receptor by Essential Polyunsaturated Fatty Acids
Published in Mini reviews in medicinal chemistry (01-01-2021)“…Vitamin-D deficiency is a global concern. Gene mutations in the vitamin D receptor's (VDR) ligand binding domain (LBD) variously alter the ligand binding…”
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Pharmacophore modelling-based drug repurposing approaches for monkeypox therapeutics
Published in Journal of biomolecular structure & dynamics (21-12-2023)“…Monkeypox is a zoonotic viral disease that mainly affects tropical rainforest regions of central and west Africa, with sporadic exportations to other places…”
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In Silico Screening of Some Active Phytochemicals to Identify Promising Inhibitors Against SARS-CoV-2 Targets
Published in Current drug discovery technologies (2024)“…There are very few small-molecule drug candidates developed against SARS-CoV-2 that have been revealed since the epidemic began in November 2019. The typical…”
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Computational Search for Potential COVID-19 Drugs from Ayurvedic Medicinal Plants to Identify Potential Inhibitors against SARS-CoV-2 Targets
Published in Current computer-aided drug design (01-01-2023)“…To date, very few small drug molecules are used for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that has been discovered since the epidemic…”
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Characterization of Sonochemical Reactor for Physicochemical Transformations
Published in Industrial & engineering chemistry research (04-11-2009)“…Complete knowledge of the pressure field distribution in a sonochemical reactor should be known for an efficient utilization of acoustic energy emitted by the…”
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Targeting a conserved pocket (n-octyl-β-D-glucoside) on the dengue virus envelope protein by small bioactive molecule inhibitors
Published in Journal of biomolecular structure & dynamics (28-06-2022)“…Dengue virus enters the cell by receptor-mediated endocytosis followed by a viral envelope (DENVE) protein-mediated membrane fusion. A small detergent molecule…”
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A numerical study on the influence of tunnel excavation on pile foundation
Published in International journal of mining and geo-engineering (01-03-2023)“…Tunnel construction in cities faces many geotechnical challenges, and the effect on pile foundation is possibly one of the most complex ones. Most tall…”
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Morphometric analysis of the anterior cruciate ligament: South Indian cadaveric study
Published in National journal of clinical anatomy (Online) (01-10-2022)“…Background: The most often damaged ligament in the knee joint is the anterior cruciate ligament (ACL). Reconstruction surgery is the ideal option which…”
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Collision Cone Control Barrier Functions for Kinematic Obstacle Avoidance in UGVs
Published in 2023 Ninth Indian Control Conference (ICC) (18-12-2023)“…In this paper, we propose a new class of Control Barrier Functions (CBFs) for Unmanned Ground Vehicles (UGVs) that help avoid collisions with kinematic…”
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Conference Proceeding -
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Frontend AC-DC Bidirectional Converter for EV
Published in 2023 IEEE 20th India Council International Conference (INDICON) (14-12-2023)“…In this article, a wide range bidirectional dc-dc converter is presented, which boasts an improved voltage gain transfer ratio that is especially suitable for…”
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Conference Proceeding -
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Computational Screening of Some Phytochemicals to Identify Best Modulators for Ligand Binding Domain of Estrogen Receptor Alpha
Published in Current pharmaceutical design (01-01-2024)“…The peculiar aim of this study is to discover and identify the most effective and potential inhibitors against the most influential target ERα receptor by in…”
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Synthesis of novel 2-phenyl-3-[2-(substituted amino) ethylamino] quinazolin-4(3H)-ones as a new class of H1-antihistaminic agents
Published in Medicinal chemistry research (01-05-2013)“…A series of novel 2-phenyl-3-[2-(substituted amino) ethylamino] quinazolin-4(3 H )-ones was synthesized by the nucleophilic substitution of 3-(2-bromo…”
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A rare case of Takayasu’s arteritis presenting with stroke
Published in Journal of Clinical and Scientific Research (01-01-2017)“…Takayasu’s arteritis is a chronic inflammatory large vessel vasculitis of unknown aetiology that commonly affects women of child bearing age. It appears to…”
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Embedded Monitoring of Covellar Carbon Monoxide Detection and Air freshening in Air Trained Automotives
Published in 2022 7th International Conference on Communication and Electronics Systems (ICCES) (22-06-2022)“…Carbon monoxide (CO) is a dry, unscented gas created as a side-effect of deficient ignition of hydrocarbons. CO ties quickly to Hemoglobin (Hb), prompting the…”
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Conference Proceeding