Search Results - "Sun Jae Lee"

LncRNAs Act as a Link between Chronic Liver Disease and Hepatocellular Carcinoma by Kim, Young-Ah, Park, Kwan-Kyu, Lee, Sun-Jae

“…Long non-coding RNAs (lncRNAs) are emerging as important contributors to the biological processes underlying the pathophysiology of various human diseases,…”
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Ultraviolet–visible–near-infrared optical properties of amyloid fibrils shed light on amyloidogenesis by Pansieri, Jonathan, Josserand, Véronique, Lee, Sun-Jae, Rongier, Anaëlle, Imbert, Daniel, Sallanon, Marcelle Moulin, Kövari, Enikö, Dane, Thomas G., Vendrely, Charlotte, Chaix-Pluchery, Odette, Guidetti, Mélanie, Vollaire, Julien, Fertin, Arnold, Usson, Yves, Rannou, Patrice, Coll, Jean-Luc, Marquette, Christel, Forge, Vincent

“…Amyloid fibres attract considerable interest due to their biological role in neurodegenerative diseases and their potential as functional biomaterials. Here,…”
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STAT3 Decoy Oligodeoxynucleotides Suppress Liver Inflammation and Fibrosis in Liver Cancer Cells and a DDC-Induced Liver Injury Mouse Model by Choi, Hye Jin, Kim, Young-Ah, Ryu, Junghwa, Park, Kwan-Kyu, Lee, Sun-Jae, Kim, Byung Seok, Song, Jeong-En, Kim, Joo Dong

“…Liver damage caused by various factors results in fibrosis and inflammation, leading to cirrhosis and cancer. Fibrosis results in the accumulation of…”
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Oridonin Attenuates Cisplatin-Induced Acute Kidney Injury via Inhibiting Oxidative Stress, Apoptosis, and Inflammation in Mice by Gu, Hyemin, Gwon, Mi-Gyeong, Kim, Jong Hyun, Leem, Jaechan, Lee, Sun-Jae

“…The use of cisplatin, a chemotherapy drug, is often limited due to its renal side effects such as acute kidney injury (AKI). However, there are no validated…”
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Chemical Constituents of Halophyte Suaeda glauca and Their Therapeutic Potential for Hair Loss by Kim, Yun-Na, Park, Min-Gyu, Kim, Yu-Jung, Lee, Jae-Sun, Kwon, Bong-Oh, Rho, Jung-Rae, Jeong, Eun-Ju

“…, a halophyte in the Amaranthaceae family, exhibits remarkable resilience to high salt and alkali stresses despite the absence of salt glands or vesicles in…”
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High impacts of cultivar and home‐cooking practice on the content of free myo‐inositol, a bioavailable health‐promoting cyclitol, in sweet potato by Lim, Su Min, Choi, Dong Seong, Chung, Mi‐Nam, Lee, Jae‐Sun, Kang, Young‐Sik, Choi, Kyu‐Hwan, Moon, Jin‐Young, Nam, Sang‐Sik, Jung, Mun Yhung

“…Free myo‐inositol is a bioavailable form of a cyclitol having various health‐promoting activities. The impact of cultivar and home‐cooking practice on the…”
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Anti-Fibrotic Effect of Synthetic Noncoding Decoy ODNs for TFEB in an Animal Model of Chronic Kidney Disease by Lee, Sun-Jae, Kim, Young-Ah, Park, Kwan-Kyu

“…Despite emerging evidence suggesting that autophagy occurs during renal interstitial fibrosis, the role of autophagy activation in fibrosis and the mechanism…”
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Protective Effects of Carnosol on Renal Interstitial Fibrosis in a Murine Model of Unilateral Ureteral Obstruction by Park, Jae-Hyung, Leem, Jaechan, Lee, Sun-Jae

“…Renal fibrosis is a common feature of chronic kidney disease and is a promising therapeutic target. However, there is still limited treatment for renal…”
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Anti-Fibrotic Effect of Synthetic Noncoding Oligodeoxynucleotide for Inhibiting mTOR and STAT3 via the Regulation of Autophagy in an Animal Model of Renal Injury by Jung, Hyun Jin, An, Hyun-Jin, Gwon, Mi-Gyeong, Gu, Hyemin, Bae, Seongjae, Lee, Sun-Jae, Kim, Young-Ah, Leem, Jaechan, Park, Kwan-Kyu

“…Renal fibrosis is a common process of various kidney diseases. Autophagy is an important cell biology process to maintain cellular homeostasis. In addition,…”
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Bee Venom and Its Major Component Melittin Attenuated Cutibacterium acnes - and IGF-1-Induced Acne Vulgaris via Inactivation of Akt/mTOR/SREBP Signaling Pathway by Gu, Hyemin, An, Hyun-Jin, Gwon, Mi-Gyeong, Bae, Seongjae, Leem, Jaechan, Lee, Sun-Jae, Han, Sang-Mi, Zouboulis, Christos C, Park, Kwan-Kyu

“…Acne vulgaris is the most common disease of the pilosebaceous unit. The pathogenesis of this disease is complex, involving increased sebum production and…”
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Therapeutic Effect of Bee Venom and Melittin on Skin Infection Caused by Streptococcus pyogenes by Bae, Seongjae, Gu, Hyemin, Gwon, Mi-Gyeong, An, Hyun-Jin, Han, Sang-Mi, Lee, Sun-Jae, Leem, Jaechan, Park, Kwan-Kyu

“…( ) bacteria cause almost all primary skin infections in humans. Bee venom (BV) and melittin (Mel) have multiple effects, including antibacterial and…”
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Anti-Amyloidogenic Effects of Asarone Derivatives From Perilla frutescens Leaves against Beta-Amyloid Aggregation and Nitric Oxide Production by Lee, Jae Eun, Kim, Nayeon, Yeo, Ji Yun, Seo, Dae-Gun, Kim, Sunggun, Lee, Jae-Sun, Hwang, Kwang Woo, Park, So-Young

“…Alzheimer's disease (AD) is a progressive, neurodegenerative brain disorder associated with loss of memory and cognitive function. Beta-amyloid (Aβ)…”
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The Disease-Modifying Effects of a Single Intra-Articular Corticosteroid Injection during the Freezing Phase of Frozen Shoulder in an Animal Model by Ahn, Yongjin, Lee, Sun-Jae, Moon, Yong Suk, Lee, Yoon-Jin, Park, Jung Hyun, Chun, Yongmin, Kwon, Dong Rak, Lee, Sang Chul

“…Although frequently prescribed for frozen shoulder, it is not known if corticosteroid injections improve the course of frozen shoulder. This study aimed to…”
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Synthetic Non-Coding RNA for Suppressing mTOR Translation to Prevent Renal Fibrosis Related to Autophagy in UUO Mouse Model by Kim, Young-Ah, Gu, Hyemin, Gwon, Mi-Gyeong, An, Hyun-Jin, Bae, Seongjae, Leem, Jaechan, Jung, Hyun Jin, Park, Kwan-Kyu, Lee, Sun-Jae

“…The global burden of chronic kidney disease is increasing, and the majority of these diseases are progressive. Special site-targeted drugs are emerging as…”
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Therapeutic strategy using novel RET/YES1 dual-target inhibitor in lung cancer by Choi, Yong June, Choi, Munkyung, Park, Jaewoo, Park, Miso, Kim, Myung Jun, Lee, Jae-sun, Oh, Su-jin, Lee, Young Joo, Shim, Wan Seob, Kim, Ji Won, Kim, Myung Jin, Kim, Yong-Chul, Kang, Keon Wook

“…Lung cancer represents a significant global health concern and stands as the leading cause of cancer-related mortality worldwide. The identification of…”
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Protective Effects of Bee Venom against Endotoxemia-Related Acute Kidney Injury in Mice by Kim, Jung-Yeon, Lee, Sun-Jae, Maeng, Young-In, Leem, Jaechan, Park, Kwan-Kyu

“…Sepsis-associated acute kidney injury (AKI) is a leading cause of death in hospitalized patients worldwide. Despite decades of effort, there is no effective…”
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Ameliorating Fibrotic Phenotypes of Keloid Dermal Fibroblasts through an Epidermal Growth Factor-Mediated Extracellular Matrix Remodeling by Kim, Hyunbum, Anggradita, Laurensia Danis, Lee, Sun-Jae, Hur, Sung Sik, Bae, Joonsuk, Hwang, Nathaniel Suk-Yeon, Nam, Seung Min, Hwang, Yongsung

“…Keloid and hypertrophic scars are skin fibrosis-associated disorders that exhibit an uncontrollable proliferation of fibroblasts and their subsequent…”
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Mechanisms of fibrogenesis in liver cirrhosis:The molecular aspects of epithelial-mesenchymal transition by Lee, Sun-Jae, Kim, Kyung-Hyun, Park, Kwan-Kyu

“…Liver injuries are repaired by fibrosis and regeneration.The cause of fibrosis and diminished regeneration,especially in liver cirrhosis,is still…”
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Regeneration of whole meniscus using meniscal cells and polymer scaffolds in a rabbit total meniscectomy model by Kang, Sun-Woong, Sun-Mi, Son, Jae-Sun, Lee, Eung-Seok, Lee, Kwon-Yong, Lee, Sang-Guk, Park, Jung-Ho, Park, Byung-Soo, Kim

“…The current treatments of meniscal lesion in knee joint are not perfect to prevent adverse effects of meniscus injury. Tissue engineering of meniscus using…”
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Association between Preoperative 18-FDG PET-CT SUVmax and Next-Generation Sequencing Results in Postoperative Ovarian Malignant Tissue in Patients with Advanced Ovarian Cancer by Ryu, Jung Min, Jeong, Yoon Young, Lee, Sun-Jae, Choi, Byung Wook, Choi, Youn Seok

“…This study investigated the association between maximum standardized uptake values (SUVmax) on preoperative 18-FDG PET-CT and next-generation sequencing (NGS)…”
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