Search Results - "Sun, Zhenliang"

Chemical Composition and Anti-Inflammatory, Cytotoxic and Antioxidant Activities of Essential Oil from Leaves of Mentha piperita Grown in China by Sun, Zhenliang, Wang, Huiyan, Wang, Jing, Zhou, Lianming, Yang, Peiming

“…The chemical composition, anti-inflammatory, cytotoxic and antioxidant activities of essential oil from leaves of Mentha piperita (MEO) grown in China were…”
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Discovery of WD-890: A novel allosteric TYK2 inhibitor for the treatment of multiple autoimmune diseases by Fang, Zhiqin, Sun, Hongyin, Wang, Yutong, Sun, Zhenliang, Yin, Mingzhu

“…Tyrosine kinase 2 (TYK2) as a member of Janus kinase (JAK) family, mainly mediates the signaling of type I interferons (IFN), interleukin-12 (IL-12) and…”
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In vitro antiviral, anti-inflammatory, and antioxidant activities of the ethanol extract of Mentha piperita L by Li, YuXian, Liu, YiBo, Ma, AiQin, Bao, Yong, Wang, Man, Sun, ZhenLiang

“…The objective of this study is to investigate the antiviral, anti-inflammatory, and antioxidant effects of the ethanol extract of Mentha piperita L. leaves…”
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Clinical significance of Fusobacterium nucleatum , epithelial-mesenchymal transition, and cancer stem cell markers in stage III/IV colorectal cancer patients by Yan, Xuebing, Liu, Liguo, Li, Hao, Qin, Huanlong, Sun, Zhenliang

“…Colorectal cancer (CRC) is a common digestive malignancy and emerging studies have closely linked its initiation and development with gut microbiota changes. (…”
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Antioxidant and antihyperlipidemic activities of polysaccharides from sea cucumber Apostichopus japonicus by Liu, Xin, Sun, Zhenliang, Zhang, Miansong, Meng, Xiumei, Xia, Xuekui, Yuan, Wenpeng, Xue, Feng, Liu, Changheng

“…► Polysaccharide was prepared from Apostichopus japonicus by enzymolysis method. ► It showed potent free radical scavenging activities in vitro. ► It also…”
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Different multi-scale structural features of oat resistant starch prepared by ultrasound combined enzymatic hydrolysis affect its digestive properties by Xia, Ji'an, Zhang, Yu, Huang, Kai, Cao, Hongwei, Sun, Qiqi, Wang, Man, Zhang, Suhua, Sun, Zhenliang, Guan, Xiao

“…[Display omitted] In this research, oat resistant starch (ORS) was prepared by autoclaving-retrogradation cycle (ORS-A), enzymatic hydrolysis (ORS-B), and…”
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A small molecule targeting myoferlin exerts promising anti-tumor effects on breast cancer by Zhang, Tao, Li, Jingjie, He, Yuan, Yang, Feifei, Hao, Yun, Jin, Wangrui, Wu, Jing, Sun, Zhenliang, Li, Yunqi, Chen, Yihua, Yi, Zhengfang, Liu, Mingyao

“…Breast cancer is one of the most lethal cancers in women when it reaches the metastatic stage. Here, we screen a library of small molecules for inhibitors of…”
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Organosilane and Polyethylene Glycol Functionalized Magnetic Mesoporous Silica Nanoparticles as Carriers for CpG Immunotherapy In Vitro and In Vivo by Zheng, Hengrui, Wen, Songsong, Zhang, Yang, Sun, Zhenliang

“…Cytosine-guanine (CpG) containing oligodeoxynucleotides (ODN) have significant clinical potential as immunotherapeutics. However, limitations exist due to…”
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CRISPR/Cas9‐mediated somatic correction of a novel coagulator factor IX gene mutation ameliorates hemophilia in mouse by Guan, Yuting, Ma, Yanlin, Li, Qi, Sun, Zhenliang, Ma, Lie, Wu, Lijuan, Wang, Liren, Zeng, Li, Shao, Yanjiao, Chen, Yuting, Ma, Ning, Lu, Wenqing, Hu, Kewen, Han, Honghui, Yu, Yanhong, Huang, Yuanhua, Liu, Mingyao, Li, Dali

“…The X‐linked genetic bleeding disorder caused by deficiency of coagulator factor IX, hemophilia B, is a disease ideally suited for gene therapy with genome…”
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High fat diet exacerbates intestinal barrier dysfunction and changes gut microbiota in intestinal-specific ACF7 knockout mice by Shi, Chenzhang, Li, Hao, Qu, Xiao, Huang, Linsheng, Kong, Cheng, Qin, Huanlong, Sun, Zhenliang, Yan, Xuebing

“…•ACF7 cKO decreases the signs of obesity under dietary intervention.•ACF7 cKO increases intestinal permeability and epithelial cell apoptosis.•HFD stimulates…”
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A New Monoterpene-Flavanone Conjugate from the Aerial Parts of Chimonanthus grammatus by Li, Yuxian, Sun, Ke, Liang, Lin, Wang, Man, Sun, Zhenliang

“…A new monoterpene-flavanone conjugate, grammatin A ( 1 ), along with four known compounds ( 2–5 ), were isolated from the aerial parts of Chimonanthus…”
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Prediction of Cholecystokinin-Secretory Peptides Using Bidirectional Long Short-term Memory Model Based on Transfer Learning and Hierarchical Attention Network Mechanism by Liu, Jing, Chen, Pu, Song, Hongdong, Zhang, Pengxiao, Wang, Man, Sun, Zhenliang, Guan, Xiao

“…Cholecystokinin (CCK) can make the human body feel full and has neurotrophic and anti-inflammatory effects. It is beneficial in treating obesity, Parkinson’s…”
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Targeting Pyruvate Carboxylase by a Small Molecule Suppresses Breast Cancer Progression by Lin, Qingxiang, He, Yuan, Wang, Xue, Zhang, Yong, Hu, Meichun, Guo, Weikai, He, Yundong, Zhang, Tao, Lai, Li, Sun, Zhenliang, Yi, Zhengfang, Liu, Mingyao, Chen, Yihua

“…Rapid metabolism differentiates cancer cells from normal cells and relies on anaplerotic pathways. However, the mechanisms of anaplerosis‐associated enzymes…”
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Targeting metabolic vulnerability in mitochondria conquers MEK inhibitor resistance in KRAS-mutant lung cancer by Feng, Juanjuan, Lian, Zhengke, Xia, Xinting, Lu, Yue, Hu, Kewen, Zhang, Yunpeng, Liu, Yanan, Hu, Longmiao, Yuan, Kun, Sun, Zhenliang, Pang, Xiufeng

“…MEK is a canonical effector of mutant KRAS; however, MEK inhibitors fail to yield satisfactory clinical outcomes in KRAS-mutant cancers. Here, we identified…”
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PD-1/PD-L1 pathway and angiogenesis dual recognizable nanoparticles for enhancing chemotherapy of malignant cancer by Sun, Zhenliang, Zhang, Yang, Cao, Duo, Wang, Xufeng, Yan, Xuebing, Li, Hao, Huang, Linsheng, Qu, Xiao, Kong, Cheng, Qin, Huanglong, Wang, Man, Xu, Wei, Liang, Lin

“…Although the cancer immunotherapy represents one of the most promising strategies for cancer treatment, the PD-1/PD-L1 pathway, which involves a…”
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Chemical Constituents of the Fruits of Lycium barbarum and their Neuroprotective Activity by Wen, Songsong, Xu, Yuwen, Niu, Chong, Liu, Qi, Zhang, Lei, Xiang, Yu, Wang, Weijian, Sun, Zhenliang

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Purification and characterization of angiotensin I converting enzyme inhibitory peptides from jellyfish Rhopilema esculentum by Liu, Xin, Zhang, Miansong, Jia, Airong, Zhang, Yonggang, Zhu, Haiming, Zhang, Chao, Sun, Zhenliang, Liu, Changheng

“…Two angiotensin I converting enzyme (ACE) inhibitory peptides were isolated from jellyfish Rhopilema esculentum protein hydrolysates prepared with pepsin and…”
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Ethyl‐N‐dodecanoyl‐l‐arginate hydrochloride combats pathogens with low‐resistance generation by membrane attack and modifies gut microbiota structure by Shao, Ting, Fan, Tingting, Tang, Wenshu, Sun, Yanting, Gao, Song, Chen, Huang, Sun, Zhenliang, Liu, Mingyao, Yi, Zhengfang

“…Summary Ethyl‐N‐dodecanoyl‐l‐arginate hydrochloride (LAE, ethyl lauroyl arginate HCl) is a cationic surfactant used as a food preservative with broad‐spectrum…”
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Discovery of the Highly Selective and Potent STAT3 Inhibitor for Pancreatic Cancer Treatment by Chen, Huang, Bian, Aiwu, Zhou, Wenbo, Miao, Ying, Ye, Jiangnan, Li, Jiahui, He, Peng, Zhang, Qiansen, Sun, Yue, Sun, Zhenliang, Ti, Chaowen, Chen, Yihua, Yi, Zhengfang, Liu, Mingyao

“…Signal transducer and activator of transcription 3 (STAT3) is an attractive cancer therapeutic target. Unfortunately, targeting STAT3 with small molecules has…”
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Discovery and Optimization of N-Substituted 2-(4-pyridinyl)thiazole carboxamides against Tumor Growth through Regulating Angiogenesis Signaling Pathways by Zhou, Wenbo, Tang, Wenshu, Sun, Zhenliang, Li, Yunqi, Dong, Yanmin, Pei, Haixiang, Peng, Yangrui, Wang, Jinhua, Shao, Ting, Jiang, Zhenran, Yi, Zhengfang, Chen, Yihua

“…Inhibition of angiogenesis is considered as one of the desirable pathways for the treatment of tumor growth and metastasis. Herein we demonstrated that a…”
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