Search Results - "Sun, Xutong"

Exogenous spermidine enhanced the water deficit tolerance of Anoectochilus roxburghii by modulating plant antioxidant enzymes and polyamine metabolism by Sun, Xutong, Lv, Aimin, Chen, Dandan, Zhang, Zili, Wang, Xuming, Zhou, Aicun, Xu, Xiaowei, Shao, Qingsong, Zheng, Ying

“…Water stress is an important factor affecting herb quality and yield and exogenous spermidine (Spd) addition can enhance dehydration tolerance of plants…”
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Novel Relationship between Mitofusin 2-Mediated Mitochondrial Hyperfusion, Metabolic Remodeling, and Glycolysis in Pulmonary Arterial Endothelial Cells by Yegambaram, Manivannan, Sun, Xutong, Flores, Alejandro Garcia, Lu, Qing, Soto, Jamie, Richards, Jaime, Aggarwal, Saurabh, Wang, Ting, Gu, Haiwei, Fineman, Jeffrey R, Black, Stephen M

“…The disruption of mitochondrial dynamics has been identified in cardiovascular diseases, including pulmonary hypertension (PH), ischemia-reperfusion injury,…”
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The mitochondrial redistribution of eNOS is involved in lipopolysaccharide induced inflammasome activation during acute lung injury by Wang, Hui, Sun, Xutong, Lu, Qing, Zemskov, Evgeny A., Yegambaram, Manivannan, Wu, Xiaomin, Wang, Ting, Tang, Haiyang, Black, Stephen M.

“…Acute lung injury (ALI) is a devastating clinical syndrome with no effective therapies. Inflammasome activation has been reported to play a critical role in…”
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Endothelin-1 induces a glycolytic switch in pulmonary arterial endothelial cells via the mitochondrial translocation of endothelial nitric oxide synthase by Sun, Xutong, Kumar, Sanjiv, Sharma, Shruti, Aggarwal, Saurabh, Lu, Qing, Gross, Christine, Rafikova, Olga, Lee, Sung Gon, Dasarathy, Sridevi, Hou, Yali, Meadows, Mary Louise, Han, Weihong, Su, Yunchao, Fineman, Jeffrey R, Black, Stephen M

“…Recent studies have indicated that, during the development of pulmonary hypertension (PH), there is a switch from oxidative phosphorylation to glycolysis in…”
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Complex I dysfunction underlies the glycolytic switch in pulmonary hypertensive smooth muscle cells by Rafikov, Ruslan, Sun, Xutong, Rafikova, Olga, Louise Meadows, Mary, Desai, Ankit A, Khalpey, Zain, Yuan, Jason X-J, Fineman, Jeffrey R, Black, Stephen M

“…ATP is essential for cellular function and is usually produced through oxidative phosphorylation. However, mitochondrial dysfunction is now being recognized as…”
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Pulmonary artery smooth muscle cell hyperproliferation and metabolic shift triggered by pulmonary overcirculation by Boehme, Jason, Sun, Xutong, Tormos, Kathryn V, Gong, Wenhui, Kellner, Manuela, Datar, Sanjeev A, Kameny, Rebecca Johnson, Yuan, Jason X-J, Raff, Gary W, Fineman, Jeffrey R, Black, Stephen M, Maltepe, Emin

“…Vascular cell hyperproliferation and metabolic reprogramming contribute to the pathophysiology of pulmonary arterial hypertension (PAH). An important cause of…”
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Activation of the mechanosensitive Ca2+ channel TRPV4 induces endothelial barrier permeability via the disruption of mitochondrial bioenergetics by Lu, Qing, Zemskov, Evgeny A., Sun, Xutong, Wang, Hui, Yegambaram, Manivannan, Wu, Xiaomin, Garcia-Flores, Alejandro, Song, Shanshan, Tang, Haiyang, Kangath, Archana, Cabanillas, Gabriela Zubiate, Yuan, Jason X.-J., Wang, Ting, Fineman, Jeffrey R., Black, Stephen M.

“…Mechanical ventilation is a life-saving intervention in critically ill patients with respiratory failure due to acute respiratory distress syndrome (ARDS), a…”
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TGF-β1 attenuates mitochondrial bioenergetics in pulmonary arterial endothelial cells via the disruption of carnitine homeostasis by Sun, Xutong, Lu, Qing, Yegambaram, Manivannan, Kumar, Sanjiv, Qu, Ning, Srivastava, Anup, Wang, Ting, Fineman, Jeffrey R., Black, Stephen M.

“…Transforming growth factor beta-1 (TGF-β1) signaling is increased and mitochondrial function is decreased in multiple models of pulmonary hypertension (PH)…”
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Prognostic nutritional index (PNI) and risk of non-alcoholic fatty liver disease and advanced liver fibrosis in US adults: Evidence from NHANES 2017–2020 by Chen, Ge, Fan, Liqing, Yang, Ting, Xu, Tingting, Wang, Zixuan, Wang, Yan, Kong, Lingling, Sun, Xutong, Chen, Kan, Xie, Qing, Zhao, Hong

“…This study explored the potential association between the Prognostic Nutritional Index (PNI) and the incidence of non-alcoholic fatty liver disease (NAFLD) and…”
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Ca²⁺/calmodulin-dependent protein kinase II contributes to hypoxic ischemic cell death in neonatal hippocampal slice cultures by Lu, Qing, Harris, Valerie A, Sun, Xutong, Hou, Yali, Black, Stephen M

“…We have recently shown that p38MAP kinase (p38MAPK) stimulates ROS generation via the activation of NADPH oxidase during neonatal hypoxia-ischemia (HI) brain…”
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PPAR-γ regulates carnitine homeostasis and mitochondrial function in a lamb model of increased pulmonary blood flow by Sharma, Shruti, Sun, Xutong, Rafikov, Ruslan, Kumar, Sanjiv, Hou, Yali, Oishi, Peter E, Datar, Sanjeev A, Raff, Gary, Fineman, Jeffrey R, Black, Stephen M

“…Carnitine homeostasis is disrupted in lambs with endothelial dysfunction secondary to increased pulmonary blood flow (Shunt). Our recent studies have also…”
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RAC1 nitration at Y32 IS involved in the endothelial barrier disruption associated with lipopolysaccharide-mediated acute lung injury by Wang, Ting, Yegambaram, Manivannan, Gross, Christine, Sun, Xutong, Lu, Qing, Wang, Hui, Wu, Xiaomin, Kangath, Archana, Tang, Haiyang, Aggarwal, Saurabh, Black, Stephen M.

“…Acute lung injury (ALI), a devastating illness induced by systemic inflammation e.g., sepsis or local lung inflammation e.g., COVID-19 mediated severe…”
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Oxygen glucose deprivation in rat hippocampal slice cultures results in alterations in carnitine homeostasis and mitochondrial dysfunction by Rau, Thomas F, Lu, Qing, Sharma, Shruti, Sun, Xutong, Leary, Gregory, Beckman, Matthew L, Hou, Yali, Wainwright, Mark S, Kavanaugh, Michael, Poulsen, David J, Black, Stephen M

“…Mitochondrial dysfunction characterized by depolarization of mitochondrial membranes and the initiation of mitochondrial-mediated apoptosis are pathological…”
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Down‐regulation of WNK1 protein kinase in neural progenitor cells suppresses cell proliferation and migration by Sun, Xutong, Gao, Luoyi, Yu, Robert K., Zeng, Guichao

“…WNK1, a Ser/Thr protein kinase, is widely expressed in many tissues. Its biological functions are largely unknown. Disruption of the WNK1 gene in mice leads to…”
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Hydrogen peroxide decreases endothelial nitric oxide synthase promoter activity through the inhibition of AP-1 activity by Kumar, Sanjiv, Sun, Xutong, Wedgwood, Stephen, Black, Stephen M

“…Previously, we have reported that endothelial nitric oxide synthase (eNOS) promoter activity is decreased in pulmonary arterial endothelial cells (PAECs) in…”
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Estradiol Increases Guanosine 5′-Triphosphate Cyclohydrolase Expression Via the Nitric Oxide-Mediated Activation of Cyclic Adenosine 5′-Monophosphate Response Element Binding Protein by Sun, Xutong, Kumar, Sanjiv, Tian, Jing, Black, Stephen M

“…A number of studies have demonstrated that estradiol can stimulate endothelial nitric oxide synthase expression and activity, resulting in enhanced nitric…”
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Role of carnitine acetyl transferase in regulation of nitric oxide signaling in pulmonary arterial endothelial cells by Sharma, Shruti, Sun, Xutong, Agarwal, Saurabh, Rafikov, Ruslan, Dasarathy, Sridevi, Kumar, Sanjiv, Black, Stephen M

“…Congenital heart defects with increased pulmonary blood flow (PBF) result in pulmonary endothelial dysfunction that is dependent, at least in part, on…”
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Immunohistochemical localization of vitellogenin in the hepatic diverticulum of the amphioxus Branchiostoma belcheri tsingtauense, with implications for the origin of the liver by Han, Li, Zhang, Shicui, Wang, Yongjun, Sun, Xutong

“…The localization of vitellogenin (Vg) remains untested in amphioxus. Western blotting analysis showed that mouse anti-amphioxus Vg sera cross-reacted with the…”
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Effectiveness of Thermoplastic Powder to Retard Self-Heating and Spontaneous Combustion of Coal by Xi, Zhilin, Sun, Xutong

“…To meet the specific requirements for storage and transportation of coal, the use of thermoplastic powder (TP) is proposed for retarding or suppressing…”
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VILI Induced Nitration of RhoA Disrupts Mitochondrial Function Through Increased Generation of Reactive Oxygen Species by Flores, Alejandro Garcia, Lu, Qing, Sun, Xutong, Black, Stephen

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