Search Results - "Sun, Xiaobo"
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Protective effects of Gypenoside XVII against cerebral ischemia/reperfusion injury via SIRT1-FOXO3A- and Hif1a-BNIP3-mediated mitochondrial autophagy
Published in Journal of translational medicine (27-12-2022)“…Mitochondrial autophagy maintains mitochondrial function and cellular homeostasis and plays a critical role in the pathological process of cerebral…”
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Excitatory Synaptic Transmission in Ischemic Stroke: A New Outlet for Classical Neuroprotective Strategies
Published in International journal of molecular sciences (19-08-2022)“…Stroke is one of the leading causes of death and disability in the world, of which ischemia accounts for the majority. There is growing evidence of changes in…”
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Gastrodin Alleviates Cognitive Dysfunction and Depressive-Like Behaviors by Inhibiting ER Stress and NLRP3 Inflammasome Activation in db/db Mice
Published in International journal of molecular sciences (10-12-2018)“…Patients with diabetes mellitus (DM) suffer more risks from diabetic encephalopathy such as cognitive dysfunction and depressive-like behaviors. Numerous…”
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Ginsenoside Rb1 as an Anti-Diabetic Agent and Its Underlying Mechanism Analysis
Published in Cells (Basel, Switzerland) (28-02-2019)“…and , two well-known medical plants with economic value, have a long history of use for managing various diseases in Asian countries. Accumulating clinical and…”
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Fe3+-Sensitive Carbon Dots for Detection of Fe3+ in Aqueous Solution and Intracellular Imaging of Fe3+ Inside Fungal Cells
Published in Frontiers in chemistry (15-01-2020)“…In this article, the Fe3+-sensitive carbon dots were obtained by means of a microwave-assisted method using glutamic acid and ethylenediamine as reactants. The…”
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Inhibiting the NLRP3 Inflammasome Activation with MCC950 Ameliorates Diabetic Encephalopathy in db/db Mice
Published in Molecules (Basel, Switzerland) (27-02-2018)“…Diabetes is associated with a high risk of developing cognitive dysfunction and neuropsychiatric disabilities, and these disease symptomsare termed diabetic…”
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Targeting Calcium Homeostasis in Myocardial Ischemia/Reperfusion Injury: An Overview of Regulatory Mechanisms and Therapeutic Reagents
Published in Frontiers in pharmacology (09-06-2020)“…Calcium homeostasis plays an essential role in maintaining excitation–contraction coupling (ECC) in cardiomyocytes, including calcium release, recapture, and…”
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The selectivity of the carboxylate groups terminated carbon dots switched by buffer solutions for the detection of multi-metal ions
Published in Sensors and actuators. B, Chemical (01-03-2017)“…•The carboxylate groups terminated carbon dots (−OOC-C-dots) were synthesized.•The carbon dots exhibited switchable selectivity to metal ions in different…”
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An In Silico Model for Predicting Drug-Induced Hepatotoxicity
Published in International journal of molecular sciences (17-04-2019)“…As one of the leading causes of drug failure in clinical trials, drug-induced liver injury (DILI) seriously impeded the development of new drugs. Assessing the…”
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Enhanced Thermal Conductivity in a Hybrid Graphite Nanoplatelet - Carbon Nanotube Filler for Epoxy Composites
Published in Advanced materials (Weinheim) (17-12-2008)“…A nanoscale hybrid filler comprising single‐walled carbon nanotubes and graphite nanoplatelets provides a synergistic effect in the enhancement of thermal…”
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Ramulus Mori (Sangzhi) Alkaloids Alleviate Diabetic Nephropathy through Improving Gut Microbiota Disorder
Published in Nutrients (20-07-2024)“…Diabetic nephropathy (DN), one of the leading causes of end-stage kidney failure worldwide, is closely associated with high mortality in diabetic patients…”
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Notoginsenoside R1 Protects db/db Mice against Diabetic Nephropathy via Upregulation of Nrf2-Mediated HO-1 Expression
Published in Molecules (Basel, Switzerland) (10-01-2019)“…Diabetic nephropathy (DN) is a leading cause of end-stage renal failure, and no effective treatment is available. Notoginsenoside R1 (NGR1) is a novel saponin…”
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13
The molecular mechanism of macrophage-adipocyte crosstalk in maintaining energy homeostasis
Published in Frontiers in immunology (08-04-2024)“…Interactions between macrophages and adipocytes in adipose tissue are critical for the regulation of energy metabolism and obesity. Macrophage polarization…”
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Protective Effects and Target Network Analysis of Ginsenoside Rg1 in Cerebral Ischemia and Reperfusion Injury: A Comprehensive Overview of Experimental Studies
Published in Cells (Basel, Switzerland) (12-12-2018)“…Cerebral ischemia-reperfusion is a complicated pathological process. The injury and cascade reactions caused by cerebral ischemia and reperfusion are…”
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15
High Performance Organic Solar Cells Based on a Twisted Bay-Substituted Tetraphenyl Functionalized Perylenediimide Electron Acceptor
Published in Advanced energy materials (01-06-2015)“…A twisted bay‐substituted tetraphenyl functionalized perylenediimide monomer (TP‐PDI) is synthesized. A high power conversion efficiency of 4.1% is achieved…”
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Saponins in Chinese Herbal Medicine Exerts Protection in Myocardial Ischemia-Reperfusion Injury: Possible Mechanism and Target Analysis
Published in Frontiers in pharmacology (14-01-2021)“…Myocardial ischemia is a high-risk disease among middle-aged and senior individuals. After thrombolytic therapy, heart tissue can potentially suffer further…”
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Forsythoside B alleviates cerebral ischemia-reperfusion injury via inhibiting NLRP3 inflammasome mediated by SIRT1 activation
Published in PloS one (17-06-2024)“…The inflammatory response is a key factor in the pathogenesis of cerebral ischemia/reperfusion injury (CIRI), and anti-inflammatory interventions may offer a…”
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Corrigendum: Ginsenoside compound K attenuates ox-LDL-mediated macrophage inflammation and foam cell formation via autophagy induction and modulating NF-kB, p38, and JNK MAPK signaling
Published in Frontiers in pharmacology (23-07-2024)“…[This corrects the article DOI: 10.3389/fphar.2020.567238.]…”
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Umbelliprenin isolated from Ferula sinkiangensis inhibits tumor growth and migration through the disturbance of Wnt signaling pathway in gastric cancer
Published in PloS one (01-07-2019)“…The traditional herb medicine Ferula sinkiangensis K. M. Shen (F. sinkiangensis) has been used to treat stomach disorders in Xinjiang District for centuries…”
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Isorhamnetin attenuates atherosclerosis by inhibiting macrophage apoptosis via PI3K/AKT activation and HO-1 induction
Published in PloS one (23-03-2015)“…Isorhamnetin (Iso) is a flavonoid compound extracted from the Chinese herb Hippophae rhamnoides L. Previous studies have revealed its anti-cancer,…”
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