Search Results - "Sun, Wanling"
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Variation characteristics and clinical significance of TP53 in patients with myeloid neoplasms
Published in Hematology (Luxembourg) (01-12-2024)“…MDS and AML characterized by variations have a poor prognosis in general. However, specifically, differences in prognosis have also been observed in patients…”
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Stanozolol improves the progression-free survival of patients with high-risk myelodysplastic syndrome after decitabine treatment
Published in International journal of hematology (01-06-2021)“…It is unknown whether adding stanozolol to decitabine for maintenance can further improve progression-free survival (PFS) and overall survival (OS) after…”
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Rapamycin is highly effective in murine models of immune-mediated bone marrow failure
Published in Haematologica (Roma) (01-10-2017)“…Acquired aplastic anemia, the prototypical bone marrow failure disease, is characterized by pancytopenia and marrow hypoplasia. Most aplastic anemia patients…”
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A Case of Follicular Lymphoma Mimicking Idiopathic Retroperitoneal Fibrosis
Published in Curēus (Palo Alto, CA) (29-11-2022)“…Retroperitoneal fibrosis (RF) is a rare disease, which can be primary (idiopathic) or secondary. We present the case of a 56-year-old patient with symptomatic…”
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Novel combined variants of WT1 and TET2 in a refractory and recurrent AML patient
Published in BMC medical genomics (13-06-2021)“…Somatic mutations in Wilms' tumor 1 (WT1) and tet methylcytosine dioxygenase 2 (TET2) genes were separately perceived as contributors to hematopoietic…”
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Oridonin inhibits DNMT3A R882 mutation-driven clonal hematopoiesis and leukemia by inducing apoptosis and necroptosis
Published in Cell death discovery (18-10-2021)“…DNA (cytosine-5)-methyltransferase 3A (DNMT3A) mutations occur in ~20% of de novo acute myeloid leukemia (AML) patients, and >50% of these mutations in AML…”
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Genetic analysis and clinical significance of a rare t(1;12)(q21;p13) in a patient with high‐risk myelodysplastic syndrome
Published in Molecular genetics & genomic medicine (01-04-2022)“…To explore the genetic and clinical features of a rare t(1;12)(q21;p13) in a patient with myelodysplastic syndrome (MDS). A 53‐year‐old male was diagnosed as…”
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Better prognosis in POEMS patients with cerebral infarction before polyneuropathy
Published in Heliyon (01-12-2022)“…POEMS syndrome is a plasma cell disease. Clinical manifestations and clinical onset are variable. In recent years, more and more cases of POEMS syndrome with…”
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Lenalidomide or bortezomib as maintenance treatment remedy the inferior impact of high-risk cytogenetic abnormalities in non-transplant patients with newly diagnosed multiple myeloma: a real-world multi-centered study in China
Published in Frontiers in oncology (20-04-2023)“…Maintenance treatment is a pivotal part in the whole process management of multiple myeloma (MM), which further deepens response and improves survival…”
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Analysis of Clonal Rearrangement Characteristics and Clinical Application Value of IGH in B-cell Non-Hodgkin's Lymphoma by Next-generation Sequencing
Published in Zhongliu fangzhi yanjiu (01-05-2024)“…Objective To investigate the clonal rearrangement characteristics and clinical application value of IGH gene in B-cell non-Hodgkin's lymphoma(B-NHL). Methods…”
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A First-in-Human Phase 1 Study of the Safety, Tolerability, and Pharmacokinetics of Polyethylene Glycol-Erythropoietin Injection, RD01, in Healthy Volunteers
Published in Blood (15-11-2022)Get full text
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COVID-19 Vaccine Acceptance/Hesitancy and Influence on Infection in Patients with Multiple Myeloma: A National-Wide Multicenter Survey in China
Published in Blood (02-11-2023)“…Background Patients with multiple myeloma (MM) are immunocompromised due to impaired humoral and cellular immunity in addition to immunosuppressive therapy…”
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A Phase I Dose-Escalation Study of The Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Polyethylene Glycol-Erythropoietin (PEG-EPO) in Healthy Subjects
Published in Clinical therapeutics (01-08-2024)“…•PEG-EPO is an extended half-life recombinant human erythropoietin.•In this trial, PEG-EPO showed an acceptable safety profile and good tolerability.•PEG-EPO…”
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Macrophage TNF-α licenses donor T cells in murine bone marrow failure and can be implicated in human aplastic anemia
Published in Blood (27-12-2018)“…Interferon-γ (IFN-γ) and tumor necrosis factor-α (TNF-α) have been implicated historically in the immune pathophysiology of aplastic anemia (AA) and other bone…”
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Ibrutinib in Combination with Rituximab and High-Dose Methotrexate in Newly Diagnosed Primary Central Nervous System Lymphoma Patients
Published in Blood (23-11-2021)“…Ibrutinib in combination with rituximab and high-dose methotrexate in newly diagnosed primary central nervous system lymphoma patients Yixian Guo, Xiaoxi Lan,…”
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Recovery of Gonadal Hormone Level Is a Potential Marker for the Response and Prognosis in POEMS Syndrome Patients Treated with Bortezomib Based Combined Chemotherapy
Published in Blood (23-11-2021)“…Background:There is no standard treatment recommendation for POMES syndrome, a rare clonal plasm cell disease. Although autologous hematopoietic stem cell…”
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Two Novel Genetic Variants Involved in the Oxygen Sensing Pathway in JAK2-unmutated Erythrocytosis
Published in Biochemical genetics (03-04-2024)“…JAK2-unmutated erythrocytosis or non-polycythemia vera erythrocytosis is a rare condition comprising both acquired and hereditary forms. Although acquired…”
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Preparation and characterization of soybean insoluble dietary fiber and its prebiotic effect on dyslipidemia and hepatic steatosis in high fat-fed C57BL/6J mice
Published in Food & function (20-09-2021)“…The potential benefits of insoluble dietary fiber (IDF) in the regulation of lipid metabolism have been reported in large prospective cohort studies although…”
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