Search Results - "Sun, Su Ming"

The Oncogenic MicroRNA miR-22 Targets the TET2 Tumor Suppressor to Promote Hematopoietic Stem Cell Self-Renewal and Transformation by Song, Su Jung, Ito, Keisuke, Ala, Ugo, Kats, Lev, Webster, Kaitlyn, Sun, Su Ming, Jongen-Lavrencic, Mojca, Manova-Todorova, Katia, Teruya-Feldstein, Julie, Avigan, David E., Delwel, Ruud, Pandolfi, Pier Paolo

“…MicroRNAs are frequently deregulated in cancer. Here we show that miR-22 is upregulated in myelodysplastic syndrome (MDS) and leukemia and its aberrant…”
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Establishment of Constitutive Model of Silicone Rubber Foams Based on Statistical Theory of Rubber Elasticity by Wei, Cheng-Sha, Lu, Ai, Sun, Su-Ming, Wei, Xing-Wen, Zho, Xiao-Yu, Sun, Jie

“…In this study, a constitutive model based on microscopic physical mechanism of silicone rubber foams was established. A theoretical statistical model of rubber…”
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A UV-Induced Genetic Network Links the RSC Complex to Nucleotide Excision Repair and Shows Dose-Dependent Rewiring by Srivas, Rohith, Costelloe, Thomas, Carvunis, Anne-Ruxandra, Sarkar, Sovan, Malta, Erik, Sun, Su Ming, Pool, Marijke, Licon, Katherine, van Welsem, Tibor, van Leeuwen, Fred, McHugh, Peter J., van Attikum, Haico, Ideker, Trey

“…Efficient repair of UV-induced DNA damage requires the precise coordination of nucleotide excision repair (NER) with numerous other biological processes…”
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A Network of Conserved Synthetic Lethal Interactions for Exploration of Precision Cancer Therapy by Srivas, Rohith, Shen, John Paul, Yang, Chih Cheng, Sun, Su Ming, Li, Jianfeng, Gross, Andrew M., Jensen, James, Licon, Katherine, Bojorquez-Gomez, Ana, Klepper, Kristin, Huang, Justin, Pekin, Daniel, Xu, Jia L., Yeerna, Huwate, Sivaganesh, Vignesh, Kollenstart, Leonie, van Attikum, Haico, Aza-Blanc, Pedro, Sobol, Robert W., Ideker, Trey

“…An emerging therapeutic strategy for cancer is to induce selective lethality in a tumor by exploiting interactions between its driving mutations and specific…”
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MicroRNA expression profiling in relation to the genetic heterogeneity of acute myeloid leukemia by Jongen-Lavrencic, Mojca, Sun, Su Ming, Dijkstra, Menno K., Valk, Peter J.M., Löwenberg, Bob

“…Acute myeloid leukemia (AML) is a highly diverse disease characterized by various cytogenetic and molecular abnormalities. MicroRNAs are small noncoding RNAs…”
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A genetic interaction map centered on cohesin reveals auxiliary factors involved in sister chromatid cohesion in S. cerevisiae by Ming Sun, Su, Batté, Amandine, Elmer, Mireille, van der Horst, Sophie C, van Welsem, Tibor, Bean, Gordon, Ideker, Trey, van Leeuwen, Fred, van Attikum, Haico

“…Eukaryotic chromosomes are replicated in interphase and the two newly duplicated sister chromatids are held together by the cohesin complex and several cohesin…”
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Clinical-grade whole genome sequencing-based haplarithmisis enables all forms of preimplantation genetic testing by Janssen, Anouk E. J., Koeck, Rebekka M., Essers, Rick, Cao, Ping, van Dijk, Wanwisa, Drüsedau, Marion, Meekels, Jeroen, Yaldiz, Burcu, van de Vorst, Maartje, de Koning, Bart, Hellebrekers, Debby M. E. I., Stevens, Servi J. C., Sun, Su Ming, Heijligers, Malou, de Munnik, Sonja A., van Uum, Chris M. J., Achten, Jelle, Hamers, Lars, Naghdi, Marjan, Vissers, Lisenka E. L. M., van Golde, Ron J. T., de Wert, Guido, Dreesen, Jos C. F. M., de Die-Smulders, Christine, Coonen, Edith, Brunner, Han G., van den Wijngaard, Arthur, Paulussen, Aimee D. C., Zamani Esteki, Masoud

“…High-throughput sequencing technologies have increasingly led to discovery of disease-causing genetic variants, primarily in postnatal multi-cell DNA samples…”
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Dot1 promotes H2B ubiquitination by a methyltransferase-independent mechanism by van Welsem, Tibor, Korthout, Tessy, Ekkebus, Reggy, Morais, Dominique, Molenaar, Thom M, van Harten, Kirsten, Poramba-Liyanage, Deepani W, Sun, Su Ming, Lenstra, Tineke L, Srivas, Rohith, Ideker, Trey, Holstege, Frank C P, van Attikum, Haico, El Oualid, Farid, Ovaa, Huib, Stulemeijer, Iris J E, Vlaming, Hanneke, van Leeuwen, Fred

“…Abstract The histone methyltransferase Dot1 is conserved from yeast to human and methylates lysine 79 of histone H3 (H3K79) on the core of the nucleosome…”
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Rad33, a new factor involved in nucleotide excision repair in Saccharomyces cerevisae by Dulk, Ben den, Sun, Su Ming, de Ruijter, Martina, Brandsma, Jourica A., Brouwer, Jaap

“…In Saccharomyces cerevisiae the Rad4-Rad23 complex is involved in initial damage recognition and responsible for recruiting the other NER proteins to the site…”
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A genetic interaction map centered on cohesin reveals auxiliary factors in sister chromatid cohesion by Sun, Su Ming, Batté, Amandine, Tittel-Elmer, Mireille, van der Horst, Sophie, van Welsem, Tibor, Bean, Gordon, Ideker, Trey, van Leeuwen, Fred, van Attikum, Haico

“…Eukaryotic chromosomes are replicated in interphase and the two newly duplicated sister chromatids are held together by the cohesin complex and several cohesin…”
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Genome sequencing as a generic diagnostic strategy for rare disease by Schobers, Gaby, Derks, Ronny, den Ouden, Amber, Swinkels, Hilde, van Reeuwijk, Jeroen, Bosgoed, Ermanno, Lugtenberg, Dorien, Sun, Su Ming, Corominas Galbany, Jordi, Weiss, Marjan, Blok, Marinus J, Olde Keizer, Richelle A C M, Hofste, Tom, Hellebrekers, Debby, de Leeuw, Nicole, Stegmann, Alexander, Kamsteeg, Erik-Jan, Paulussen, Aimee D C, Ligtenberg, Marjolijn J L, Bradley, Xiangqun Zheng, Peden, John, Gutierrez, Alejandra, Pullen, Adam, Payne, Tom, Gilissen, Christian, van den Wijngaard, Arthur, Brunner, Han G, Nelen, Marcel, Yntema, Helger G, Vissers, Lisenka E L M

“…To diagnose the full spectrum of hereditary and congenital diseases, genetic laboratories use many different workflows, ranging from karyotyping to exome…”
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MicroRNA-223 dose levels fine tune proliferation and differentiation in human cord blood progenitors and acute myeloid leukemia by Gentner, Bernhard, Pochert, Nicole, Rouhi, Arefeh, Boccalatte, Francesco, Plati, Tiziana, Berg, Tobias, Sun, Su Ming, Mah, Sarah M, Mirkovic-Hösle, Milijana, Ruschmann, Jens, Muranyi, Andrew, Leierseder, Simon, Argiropoulos, Bob, Starczynowski, Daniel T, Karsan, Aly, Heuser, Michael, Hogge, Donna, Camargo, Fernando D, Engelhardt, Stefan, Döhner, Hartmut, Buske, Christian, Jongen-Lavrencic, Mojca, Naldini, Luigi, Humphries, R. Keith, Kuchenbauer, Florian

“…A precise understanding of the role of miR-223 in human hematopoiesis and in the pathogenesis of acute myeloid leukemia (AML) is still lacking. By measuring…”
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Chl1 helicase controls replication fork progression by regulating dNTP pools by Batté, Amandine, van der Horst, Sophie C, Tittel-Elmer, Mireille, Sun, Su Ming, Sharma, Sushma, van Leeuwen, Jolanda, Chabes, Andrei, van Attikum, Haico

“…Eukaryotic cells have evolved a replication stress response that helps to overcome stalled/collapsed replication forks and ensure proper DNA replication. The…”
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Abstract NG02: A network of deeply conserved synthetic-lethal interactions for exploration of precision cancer therapy by Shen, John Paul, Srivas, Rohith, Yang, Chih Cheng, Sun, Su Ming, Li, Jian Feng, Gross, Andrew, Jensen, James, Licon, Kate, Bojoquez-Gomez, Ana, Klepper, Kristin, van Attikum, Haico, Aza-Blanc, Pedro, Sobol, Robert, Ideker, Trey

“…Abstract An emerging therapeutic strategy for cancer is to induce selective lethality in a tumor by exploiting interactions between its driving mutations and…”
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Chemogenetic profiling identifies RAD17 as synthetically lethal with checkpoint kinase inhibition by Shen, John Paul, Srivas, Rohith, Gross, Andrew, Li, Jianfeng, Jaehnig, Eric J, Sun, Su Ming, Bojorquez-Gomez, Ana, Licon, Katherine, Sivaganesh, Vignesh, Xu, Jia L, Klepper, Kristin, Yeerna, Huwate, Pekin, Daniel, Qiu, Chu Ping, van Attikum, Haico, Sobol, Robert W, Ideker, Trey

“…Chemical inhibitors of the checkpoint kinases have shown promise in the treatment of cancer, yet their clinical utility may be limited by a lack of molecular…”
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Prognostic and Functional Relevance of Aberrant Microrna-9/9 Expression in Acute Myeloid Leukemia by Sun, Su Ming, Nowek, Katarzyna, Bullinger, Lars, Dijkstra, Menno, Valk, Peter J.M., Dohner, Hartmut, Erkeland, Stefan J., Lowenberg, Bob, Jongen-Lavrencic, Mojca

“…Abstract 2542▪▪This icon denotes a clinically relevant abstract Acute myeloid leukemia (AML) is a highly diverse disease characterized by various cytogenetic…”
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MicroRNA Profiling In Multiple Myeloma by Corthals, Sophie, Sun, Su Ming, Kuiper, Rowan, de Knegt, Yvonne, Broyl, Annemiek, van der Holt, Bronno, Beverloo, H. Berna, Peeters, Justine K, van Duin, Mark, Lokhorst, Henk M, Zweegman, Sonja, Jongen-Lavrencic, Mojca, Sonneveld, P.

“…Abstract 302 Multiple Myeloma (MM) is a plasma cell malignancy, characterized by the accumulation of malignant plasma cells in the bone marrow (BM). Prognostic…”
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MicroRNAs in Normal Human Terminal Granulocytic Differentiation by Sun, Su Ming, Dijkstra, Menno K, Bijkerk, André C, Brooijmans, Rik, Valk, Peter J, Erkeland, Stefan J, Löwenberg, Bob, Jongen-Lavrencic, Mojca

“…Abstract 1463 Poster Board I-486 Normal human myelopoiesis is a complex biological process, where the balance between cell proliferation, differentiation and…”
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Rad33, a new factor involved in nucleotide excision repair in Saccharomyces cerevisiae by den Dulk, Ben, Sun, Su Ming, de Ruijter, Martina, Brandsma, Jourica A, Brouwer, Jaap

“…In Saccharomyces cerevisiae the Rad4-Rad23 complex is involved in initial damage recognition and responsible for recruiting the other NER proteins to the site…”
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Review of the first principles calculations and the design of cathode materials for Li-ion batteries by Yan, Liu-Ming, Su, Jun-Ming, Sun, Chao, Yue, Bao-Hua

“…Cathode materials are the most critical challenge for the large scale application of Li-ion batteries in electric vehicles and for the storages of electricity…”
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