Search Results - "Sun, Shihui"

Molecular Mechanism for Antibody-Dependent Enhancement of Coronavirus Entry by Wan, Yushun, Shang, Jian, Sun, Shihui, Tai, Wanbo, Chen, Jing, Geng, Qibin, He, Lei, Chen, Yuehong, Wu, Jianming, Shi, Zhengli, Zhou, Yusen, Du, Lanying, Li, Fang

“…Antibody-dependent enhancement (ADE) of viral entry has been a major concern for epidemiology, vaccine development, and antibody-based drug therapy. However,…”
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CD147-spike protein is a novel route for SARS-CoV-2 infection to host cells by Wang, Ke, Chen, Wei, Zhang, Zheng, Deng, Yongqiang, Lian, Jian-Qi, Du, Peng, Wei, Ding, Zhang, Yang, Sun, Xiu-Xuan, Gong, Li, Yang, Xu, He, Lei, Zhang, Lei, Yang, Zhiwei, Geng, Jie-Jie, Chen, Ruo, Zhang, Hai, Wang, Bin, Zhu, Yu-Meng, Nan, Gang, Jiang, Jian-Li, Li, Ling, Wu, Jiao, Lin, Peng, Huang, Wan, Xie, Liangzhi, Zheng, Zhao-Hui, Zhang, Kui, Miao, Jin-Lin, Cui, Hong-Yong, Huang, Min, Zhang, Jun, Fu, Ling, Yang, Xiang-Min, Zhao, Zhongpeng, Sun, Shihui, Gu, Hongjing, Wang, Zhe, Wang, Chun-Fu, Lu, Yacheng, Liu, Ying-Ying, Wang, Qing-Yi, Bian, Huijie, Zhu, Ping, Chen, Zhi-Nan

“…In face of the everlasting battle toward COVID-19 and the rapid evolution of SARS-CoV-2, no specific and effective drugs for treating this disease have been…”
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Structural basis for neutralization of SARS-CoV-2 and SARS-CoV by a potent therapeutic antibody by Lv, Zhe, Deng, Yong-Qiang, Ye, Qing, Cao, Lei, Sun, Chun-Yun, Fan, Changfa, Huang, Weijin, Sun, Shihui, Sun, Yao, Zhu, Ling, Chen, Qi, Wang, Nan, Nie, Jianhui, Cui, Zhen, Zhu, Dandan, Shaw, Neil, Li, Xiao-Feng, Li, Qianqian, Xie, Liangzhi, Wang, Youchun, Rao, Zihe, Qin, Cheng-Feng, Wang, Xiangxi

“…The coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has resulted in an unprecedented public…”
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Adaptation of SARS-CoV-2 in BALB/c mice for testing vaccine efficacy by Gu, Hongjing, Chen, Qi, Yang, Guan, He, Lei, Fan, Hang, Deng, Yong-Qiang, Wang, Yanxiao, Teng, Yue, Zhao, Zhongpeng, Cui, Yujun, Li, Yuchang, Li, Xiao-Feng, Li, Jiangfan, Zhang, Na-Na, Yang, Xiaolan, Chen, Shaolong, Guo, Yan, Zhao, Guangyu, Wang, Xiliang, Luo, De-Yan, Wang, Hui, Yang, Xiao, Li, Yan, Han, Gencheng, He, Yuxian, Zhou, Xiaojun, Geng, Shusheng, Sheng, Xiaoli, Jiang, Shibo, Sun, Shihui, Qin, Cheng-Feng, Zhou, Yusen

“…The ongoing coronavirus disease 2019 (COVID-19) pandemic has prioritized the development of small-animal models for severe acute respiratory syndrome…”
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Characterization and structural basis of a lethal mouse-adapted SARS-CoV-2 by Sun, Shihui, Gu, Hongjing, Cao, Lei, Chen, Qi, Ye, Qing, Yang, Guan, Li, Rui-Ting, Fan, Hang, Deng, Yong-Qiang, Song, Xiaopeng, Qi, Yini, Li, Min, Lan, Jun, Feng, Rui, Guo, Yan, Zhu, Na, Qin, Si, Wang, Lei, Zhang, Yi-Fei, Zhou, Chao, Zhao, Lingna, Chen, Yuehong, Shen, Meng, Cui, Yujun, Yang, Xiao, Wang, Xinquan, Tan, Wenjie, Wang, Hui, Wang, Xiangxi, Qin, Cheng-Feng

“…There is an urgent need for animal models to study SARS-CoV-2 pathogenicity. Here, we generate and characterize a novel mouse-adapted SARS-CoV-2 strain,…”
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Ultrasonic-Assisted Rock-Breaking Technology and Oil and Gas Drilling Applications: A Review by Feng, Jinyu, Yan, Tie, Cao, Yang, Sun, Shihui

“…High-efficiency rock-breaking is a problem that has long been studied in the oil- and gas-drilling industry. The successful use of ultrasonic technology in…”
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Introduction of neutralizing immunogenicity index to the rational design of MERS coronavirus subunit vaccines by Du, Lanying, Tai, Wanbo, Yang, Yang, Zhao, Guangyu, Zhu, Qing, Sun, Shihui, Liu, Chang, Tao, Xinrong, Tseng, Chien-Te K., Perlman, Stanley, Jiang, Shibo, Zhou, Yusen, Li, Fang

“…Viral subunit vaccines often contain immunodominant non-neutralizing epitopes that divert host immune responses. These epitopes should be eliminated in vaccine…”
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A Novel Nanobody Targeting Middle East Respiratory Syndrome Coronavirus (MERS-CoV) Receptor-Binding Domain Has Potent Cross-Neutralizing Activity and Protective Efficacy against MERS-CoV by Zhao, Guangyu, He, Lei, Sun, Shihui, Qiu, Hongjie, Tai, Wanbo, Chen, Jiawei, Li, Jiangfan, Chen, Yuehong, Guo, Yan, Wang, Yufei, Shang, Jian, Ji, Kaiyuan, Fan, Ruiwen, Du, Enqi, Jiang, Shibo, Li, Fang, Du, Lanying, Zhou, Yusen

“…The newly emerged Middle East respiratory syndrome coronavirus (MERS-CoV) continues to infect humans and camels, calling for efficient, cost-effective, and…”
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Frictional Pressure Drop for Gas–Liquid Two-Phase Flow in Coiled Tubing by Sun, Shihui, Liu, Jiahao, Zhang, Wan, Yi, Tinglong

“…Coiled tubing (CT) is widely used in drilling, workover, completion, fracturing and stimulation in the field of oil and gas exploration and development. During…”
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Features and Constitutive Model of Hydrate-Bearing Sandy Sediment’s Triaxial Creep Failure by Sun, Shihui, Zhang, Xiaohan, Zhou, Yunjian

“…In the longstanding development of hydrate-bearing sediment (HBS) reservoirs, slow and permanent deformation of the formation will occur under the influence of…”
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Peptides-Based Vaccine MP3RT Induced Protective Immunity Against Mycobacterium Tuberculosis Infection in a Humanized Mouse Model by Gong, Wenping, Liang, Yan, Mi, Jie, Jia, Zaixing, Xue, Yong, Wang, Jie, Wang, Lan, Zhou, Yusen, Sun, Shihui, Wu, Xueqiong

“…Tuberculosis (TB) is still a global infectious disease that seriously threatens human beings. The only licensed TB vaccine Bacille Calmette-Guérin (BCG)'s…”
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Mxi1 participates in the progression of lung cancer via the microRNA-300/KLF9/GADD34 Axis by Lei, Yujie, Huang, Yunchao, Lin, Jianbin, Sun, Shihui, Che, Keda, Shen, Junting, Liao, Jun, Chen, Yangming, Chen, Kai, Lin, Zhaoxian, Lin, Xing

“…The purpose of the current study was to define the role of MAX interactor 1 (Mxi1) in the pathogenesis of lung cancer and its underlying molecular mechanism…”
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Recombinant vaccine containing an RBD-Fc fusion induced protection against SARS-CoV-2 in nonhuman primates and mice by Sun, Shihui, He, Lei, Zhao, Zhongpeng, Gu, Hongjing, Fang, Xin, Wang, Tiecheng, Yang, Xiaolan, Chen, Shaolong, Deng, Yongqiang, Li, Jiangfan, Zhao, Jian, Li, Liang, Li, Xinwang, He, Peng, Li, Ge, Li, Hao, Zhao, Yuee, Gao, Chunrun, Lang, Xiaoling, Wang, Xin, Fei, Guoqiang, Li, Yan, Geng, Shusheng, Gao, Yuwei, Wei, Wenjin, Hu, Zhongyu, Han, Gencheng, Sun, Yansong

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Case report: Overlapping anti-AMPAR encephalitis with anti-IgLON5 disease post herpes simplex virus encephalitis by Sun, Shihui, Ren, Jiafeng, Zhong, Zhao, Ma, Xuxia, Shang, Danqing, Su, Changjun, Zhao, Xianchao

“…Autoimmune encephalitis (AE) is the result of an autoimmune process that occurs as a rapidly advancing encephalopathy. Autoimmune encephalitis was commonly…”
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Identification of a Receptor-Binding Domain in the S Protein of the Novel Human Coronavirus Middle East Respiratory Syndrome Coronavirus as an Essential Target for Vaccine Development by Du, Lanying, Zhao, Guangyu, Kou, Zhihua, Ma, Cuiqing, Sun, Shihui, Poon, Vincent K M, Lu, Lu, Wang, Lili, Debnath, Asim K, Zheng, Bo-Jian, Zhou, Yusen, Jiang, Shibo

“…Erratum ( vol. 87 , p. 11963 ) Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious…”
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Rational development of a human antibody cocktail that deploys multiple functions to confer Pan-SARS-CoVs protection by Yao, Hangping, Sun, Yao, Deng, Yong-Qiang, Wang, Nan, Tan, Yongcong, Zhang, Na-Na, Li, Xiao-Feng, Kong, Chao, Xu, Yan-Peng, Chen, Qi, Cao, Tian-Shu, Zhao, Hui, Yan, Xintian, Cao, Lei, Lv, Zhe, Zhu, Dandan, Feng, Rui, Wu, Nanping, Zhang, Wenhai, Hu, Yuhao, Chen, Keda, Zhang, Rong-Rong, Lv, Qingyu, Sun, Shihui, Zhou, Yunhua, Yan, Run, Yang, Guan, Sun, Xinglu, Liu, Chanjuan, Lu, Xiangyun, Cheng, Linfang, Qiu, Hongying, Huang, Xing-Yao, Weng, Tianhao, Shi, Danrong, Jiang, Weidong, Shao, Junbin, Wang, Lei, Zhang, Jie, Jiang, Tao, Lang, Guojun, Qin, Cheng-Feng, Li, Lanjuan, Wang, Xiangxi

“…Structural principles underlying the composition and synergistic mechanisms of protective monoclonal antibody cocktails are poorly defined. Here, we exploited…”
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Oncolytic Parapoxvirus induces Gasdermin E-mediated pyroptosis and activates antitumor immunity by Lin, Jing, Sun, Shihui, Zhao, Kui, Gao, Fei, Wang, Renling, Li, Qi, Zhou, Yanlong, Zhang, Jing, Li, Yue, Wang, Xinyue, Du, Le, Wang, Shuai, Li, Zi, Lu, Huijun, Lan, Yungang, Song, Deguang, Guo, Wei, Chen, Yujia, Gao, Feng, Zhao, Yicheng, Fan, Rongrong, Guan, Jiyu, He, Wenqi

“…The advantage of oncolytic viruses (OV) in cancer therapy is their dual effect of directly killing tumours while prompting anti-tumour immune response…”
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Multi-Organ Damage in Human Dipeptidyl Peptidase 4 Transgenic Mice Infected with Middle East Respiratory Syndrome-Coronavirus by Zhao, Guangyu, Jiang, Yuting, Qiu, Hongjie, Gao, Tongtong, Zeng, Yang, Guo, Yan, Yu, Hong, Li, Junfeng, Kou, Zhihua, Du, Lanying, Tan, Wenjie, Jiang, Shibo, Sun, Shihui, Zhou, Yusen

“…The Middle East Respiratory Syndrome Coronavirus (MERS-CoV) causes severe acute respiratory failure and considerable extrapumonary organ dysfuction with…”
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Complement Receptor C5aR1 Inhibition Reduces Pyroptosis in hDPP4-Transgenic Mice Infected with MERS-CoV by Jiang, Yuting, Li, Junfeng, Teng, Yue, Sun, Hong, Tian, Guang, He, Lei, Li, Pei, Chen, Yuehong, Guo, Yan, Li, Jiangfan, Zhao, Guangyu, Zhou, Yusen, Sun, Shihui

“…Middle East respiratory syndrome coronavirus (MERS-CoV) is a highly pathogenic virus with a crude mortality rate of ~35%. Previously, we established a human…”
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Human intestinal tract serves as an alternative infection route for Middle East respiratory syndrome coronavirus by Zhou, Jie, Li, Cun, Zhao, Guangyu, Chu, Hin, Wang, Dong, Yan, Helen Hoi-Ning, Poon, Vincent Kwok-Man, Wen, Lei, Wong, Bosco Ho-Yin, Zhao, Xiaoyu, Chiu, Man Chun, Yang, Dong, Wang, Yixin, Au-Yeung, Rex K H, Chan, Ivy Hau-Yee, Sun, Shihui, Chan, Jasper Fuk-Woo, To, Kelvin Kai-Wang, Memish, Ziad A, Corman, Victor M, Drosten, Christian, Hung, Ivan Fan-Ngai, Zhou, Yusen, Leung, Suet Yi, Yuen, Kwok-Yung

“…Middle East respiratory syndrome coronavirus (MERS-CoV) has caused human respiratory infections with a high case fatality rate since 2012. However, the mode of…”
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