Search Results - "Sun, Shawn W"

Activation of Neuronal Gene Expression by the JMJD3 Demethylase Is Required for Postnatal and Adult Brain Neurogenesis by Park, Dae Hwi, Hong, Sung Jun, Salinas, Ryan D., Liu, Siyuan John, Sun, Shawn W., Sgualdino, Jacopo, Testa, Giuseppe, Matzuk, Martin M., Iwamori, Naoki, Lim, Daniel A.

“…The epigenetic mechanisms that enable lifelong neurogenesis from neural stem cells (NSCs) in the adult mammalian brain are poorly understood. Here, we show…”
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Important Surgical and Clinical End Points in Neoadjuvant Immunotherapy Trials in Resectable NSCLC by Lee, Jay M., Kim, Anthony W., Marjanski, Tomasz, Falcoz, Pierre-Emmanuel, Tsuboi, Masahiro, Wu, Yi-Long, Sun, Shawn W., Gitlitz, Barbara J.

“…Neoadjuvant immunotherapy may improve outcomes in patients with resectable NSCLC and is being evaluated in phase 2 and 3 studies. Nevertheless, preoperative…”
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Assessing Pathologic Response in Resected Lung Cancers: Current Standards, Proposal for a Novel Pathologic Response Calculator Tool, and Challenges in Practice by Saqi, Anjali, Leslie, Kevin O., Moreira, Andre L., Lantuejoul, Sylvie, Shu, Catherine Ann, Rizvi, Naiyer A., Sonett, Joshua R., Tajima, Kosei, Sun, Shawn W., Gitlitz, Barbara J., Colby, Thomas V.

“…The efficacy of neoadjuvant treatment for NSCLC can be pathologically assessed in resected tissue. Major pathologic response (MPR) and pathologic complete…”
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Atezolizumab in Combination With Carboplatin and Nab-Paclitaxel in Advanced Squamous NSCLC (IMpower131): Results From a Randomized Phase III Trial by Jotte, Robert, Cappuzzo, Federico, Vynnychenko, Ihor, Stroyakovskiy, Daniil, Rodríguez-Abreu, Delvys, Hussein, Maen, Soo, Ross, Conter, Henry J, Kozuki, Toshiyuki, Huang, Kuan-Chieh, Graupner, Vilma, Sun, Shawn W, Hoang, Tien, Jessop, Helen, McCleland, Mark, Ballinger, Marcus, Sandler, Alan, Socinski, Mark A

“…Cytotoxic agents have immunomodulatory effects, providing a rationale for combining atezolizumab (anti-programmed death-ligand 1 [anti-PD-L1]) with…”
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ASCENT-05/OptimICE-RD (AFT-65): Phase 3, randomized, open-label study of adjuvant sacituzumab govitecan (SG) + pembrolizumab (pembro) vs pembro ± capecitabine (cape) in patients (pts) with triple-negative breast cancer (TNBC) and residual disease after neoadjuvant therapy (NAT) and surgery by Tolaney, Sara M., DeMichele, Angela, Takano, Toshimi, Rugo, Hope S., Perou, Charles, Metzger, Otto, Parsons, Heather Anne, Santa-Maria, Cesar Augusto, Rocque, Gabrielle Betty, Yao, Wenliang, Sun, Shawn W., Mocci, Simonetta, Partridge, Ann H., Carey, Lisa A.

“…TPS619 Background: TNBC has an aggressive disease course with poor prognosis for pts with residual disease (RD) after NAT. In Ph 3 KEYNOTE-522, pts treated…”
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Epigenetic Activation of Neuronal Gene Expression by JMJD3 is Required for Postnatal and Adult Brain Neurogenesis by Park, Dae Hwi, Hong, Sung Jun, Salinas, Ryan D., Liu, Siyuan John, Sun, Shawn W., Sgualdino, Jacopo, Testa, Giuseppe, Matzuk, Martin M., Iwamori, Naoki, Lim, Daniel A.

“…The epigenetic mechanisms that enable lifelong neurogenesis from neural stem cells (NSCs) in the adult mammalian brain are poorly understood. Here we show that…”
Get full text