Search Results - "Sun, Madi"
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Circulating Cell‐Free DNAs as a Biomarker and Therapeutic Target for Acetaminophen‐Induced Liver Injury
Published in Advanced science (01-06-2023)“…Acetaminophen (APAP) overdose is a leading cause of drug‐induced liver injury and acute liver failure, while the detection, prognosis prediction, and therapy…”
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2
Hepatic‐Accumulated Obeticholic Acid and Atorvastatin Self‐Assembled Nanocrystals Potentiate Ameliorative Effects in Treatment of Metabolic‐Associated Fatty Liver Disease
Published in Advanced science (01-03-2024)“…Exploration of medicines for efficient and safe management of metabolic‐associated fatty liver disease (MAFLD) remains a challenge. Obeticholic acid (OCA), a…”
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3
Green synthesis of carrier-free curcumin nanodrugs for light-activated breast cancer photodynamic therapy
Published in Colloids and surfaces, B, Biointerfaces (01-08-2019)“…[Display omitted] •Carrier-free curcumin nanodrugs is fabricated through green reprecipitation method.•Cur NDs exhibit light-triggered drug release manner.•Cur…”
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4
Bioactive Injectable Hydrogel Dressings for Bacteria-Infected Diabetic Wound Healing: A “Pull–Push” Approach
Published in ACS applied materials & interfaces (15-06-2022)“…Chronic diabetic wound healing remains a challenge due to the existence of excessive danger molecules and bacteria in the inflammatory microenvironment. There…”
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Biomimetic co-assembled nanodrug of doxorubicin and berberine suppresses chemotherapy-exacerbated breast cancer metastasis
Published in Biomaterials (01-04-2021)“…Chemotherapy is a major approach for treating breast cancer patients. Paradoxically, it can also induce cancer progression. Understanding post-chemotherapy…”
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Janus nanocarrier-based co-delivery of doxorubicin and berberine weakens chemotherapy-exacerbated hepatocellular carcinoma recurrence
Published in Acta biomaterialia (01-12-2019)“…Despite the rapid progress which has been made in hepatocellular carcinoma (HCC) chemotherapeutics, recurrence of liver cancer still remains a barrier to…”
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Immunogenicity-masking delivery of uricase against hyperuricemia and gout
Published in Journal of controlled release (01-08-2024)“…Improving the activity of uricase and lowering its immunogenicity remain significant challenges in the enzyme replacement management of hyperuricemia and…”
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8
Depression promotes hepatocellular carcinoma progression through a glucocorticoid-mediated upregulation of PD-1 expression in tumor-infiltrating NK cells
Published in Carcinogenesis (New York) (18-09-2019)“…There is a growing belief that depression was positively associated with the progression of liver cancer. However, the driving molecular events behind the…”
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9
An Engineered Nanoplatform with Tropism Toward Irradiated Glioblastoma Augments Its Radioimmunotherapy Efficacy
Published in Advanced materials (Weinheim) (01-08-2024)“…Combining radiotherapy with immune checkpoint blockade therapy offers a promising approach to treat glioblastoma multiforme (GBM), yet challenges such as…”
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10
Portable and visual quantification of urine cell-free DNA through smartphone-based colorimetric biosensor
Published in Sensors and actuators. B, Chemical (01-01-2024)“…The trace amount of cell-free DNA (cfDNA) in urine provides a promising diagnosis of urological disease, but its clinical applications are restricted by…”
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A nanoparticulate dual scavenger for targeted therapy of inflammatory bowel disease
Published in Science advances (28-01-2022)“…A therapeutic strategy that targets multiple proinflammatory factors in inflammatory bowel disease (IBD) with minimal systemic side effects would be…”
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12
Engineering a biomimetic system for hepatocyte-specific RNAi treatment of non-alcoholic fatty liver disease
Published in Acta biomaterialia (15-01-2024)“…RNA interference (RNAi) presents great potential against intractable liver diseases. However, the establishment of specific, efficient, and safe delivery…”
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13
Treatment of severe sepsis with nanoparticulate cell-free DNA scavengers
Published in Science advances (01-05-2020)“…Severe sepsis represents a common, expensive, and deadly health care issue with limited therapeutic options. Gaining insights into the inflammatory…”
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14
5-FU preferably induces apoptosis in BRAF V600E colorectal cancer cells via downregulation of Bcl-x.sub.L
Published in Molecular and cellular biochemistry (01-11-2019)“…Fluorouracil (5-FU) which has been widely used in postoperative adjuvant therapy in patients with colon cancer, remains the main backbone of combination…”
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15
Self-assembled dual fluorescence nanoparticles for CD44-targeted delivery of anti-miR-27a in liver cancer theranostics
Published in Theranostics (01-01-2018)“…Despite the vital role miRNA-27a plays in driving the development and progress of liver cancer, miRNA-based inhibition therapy is hampered due to its undesired…”
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5-FU preferably induces apoptosis in BRAF V600E colorectal cancer cells via downregulation of Bcl-xL
Published in Molecular and cellular biochemistry (01-11-2019)“…Fluorouracil (5-FU) which has been widely used in postoperative adjuvant therapy in patients with colon cancer, remains the main backbone of combination…”
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17
Berberine-based carbon dots for selective and safe cancer theranostics
Published in RSC advances (01-01-2018)“…Fluorescent berberine-based carbon dots (Ber-CDs) were prepared through a facile synthesis strategy. Ber-CDs exhibited excellent optical properties for…”
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Tannic Acid-Assisted Synthesis of Biodegradable and Antibacterial Mesoporous Organosilica Nanoparticles Decorated with Nanosilver
Published in ACS sustainable chemistry & engineering (27-01-2020)“…Metal/silica nanoparticles (NPs) have long been used as antibacterial substitutes; however, fabrication of a degradable carrier for achieving sustained release…”
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One-pot synthesis of chlorhexidine-templated biodegradable mesoporous organosilica nanoantiseptics
Published in Colloids and surfaces, B, Biointerfaces (01-03-2020)“…[Display omitted] •Biodegradable mesoporous organosilica nanoparticles are fabricated via a one-pot synthesis.•Chlorhexidine (CHX) is selected as a cationic…”
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Berberine Inhibits the Apoptosis-Induced Metastasis by Suppressing the iPLA2/LOX-5/LTB4 Pathway in Hepatocellular Carcinoma
Published in OncoTargets and therapy (01-01-2020)“…Hepatocellular carcinoma (HCC) is one of the most malignant cancers around the world. HCC is less sensitive to conventional cytotoxic agents and easily…”
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