Search Results - "Sun, Lun‐Quan"
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1
EIF2A promotes cell survival during paclitaxel treatment in vitro and in vivo
Published in Journal of cellular and molecular medicine (01-09-2019)“…The integrated stress response (ISR) is critical for cancer cell survival during stress stimuli and has been implicated in the resistance to cancer…”
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2
Molecular mechanisms and treatment of radiation-induced lung fibrosis
Published in Current drug targets (01-10-2013)“…Radiation-induced lung fibrosis (RILF) is a severe side effect of radiotherapy in lung cancer patients that presents as a progressive pulmonary injury combined…”
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3
DIAPH3 promotes pancreatic cancer progression by activating selenoprotein TrxR1‐mediated antioxidant effects
Published in Journal of cellular and molecular medicine (01-02-2021)“…Pancreatic cancer is a highly malignant tumour of the digestive tract which is difficult to diagnose and treat. Approximately 90% of cases arise from…”
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4
Fatty acid oxidation fuels glioblastoma radioresistance with CD47-mediated immune evasion
Published in Nature communications (21-03-2022)“…Glioblastoma multiforme (GBM) remains the top challenge to radiotherapy with only 25% one-year survival after diagnosis. Here, we reveal that co-enhancement of…”
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5
Glutamine Synthetase Promotes Radiation Resistance via Facilitating Nucleotide Metabolism and Subsequent DNA Damage Repair
Published in Cell reports (Cambridge) (30-07-2019)“…Radiation resistance is a critical problem in radiotherapy for cancer. Radiation kills tumor cells mainly through causing DNA damage. Thus, efficiency of DNA…”
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6
Dual blockade of CD47 and HER2 eliminates radioresistant breast cancer cells
Published in Nature communications (14-09-2020)“…Although the efficacy of cancer radiotherapy (RT) can be enhanced by targeted immunotherapy, the immunosuppressive factors induced by radiation on tumor cells…”
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7
The regulation of radiosensitivity by p53 and its acetylation
Published in Cancer letters (28-07-2015)“…Highlights • Post translational modifications of P53 play critical roles in cellular response to radiation. • P53 acetylation/deacetylation modulates key…”
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8
Downregulation of Fat Mass and Obesity Associated (FTO) Promotes the Progression of Intrahepatic Cholangiocarcinoma
Published in Frontiers in oncology (09-05-2019)“…Intrahepatic cholangiocarcinoma (ICC) ranks as the second most malignant type of primary liver cancer with a high degree of incidence and a very poor…”
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9
NEK4 kinase regulates EMT to promote lung cancer metastasis
Published in Journal of cellular and molecular medicine (01-12-2018)“…Epithelial‐to‐mesenchymal transition (EMT) is a dynamic transitional state from the epithelial to mesenchymal phenotypes. Numerous studies have suggested that…”
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10
Current and future developments in the treatment of virus-induced hypercytokinemia
Published in Future medicinal chemistry (01-02-2017)“…Emerging pathogenic viruses such as Ebola and Middle Eastern Respiratory Syndrome coronavirus (MERS-CoV) can cause acute infections through the evasion of the…”
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11
CDK1-Mediated SIRT3 Activation Enhances Mitochondrial Function and Tumor Radioresistance
Published in Molecular cancer therapeutics (01-09-2015)“…Tumor adaptive resistance to therapeutic radiation remains a barrier for further improvement of local cancer control. SIRT3, a member of the sirtuin family of…”
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12
Hepatitis B virus X protein inhibits apoptosis by modulating endoplasmic reticulum stress response
Published in Oncotarget (10-11-2017)“…Chronic Hepatitis B virus (HBV) infection is a major risk of hepatocellular carcinoma (HCC) worldwide. Hepatitis B virus X protein (HBx) is encoded by one of…”
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13
Asparagine synthetase regulates lung-cancer metastasis by stabilizing the β-catenin complex and modulating mitochondrial response
Published in Cell death & disease (23-06-2022)“…The availability of asparagine is the limitation of cell growth and metastasis. Asparagine synthetase (ASNS) was an essential enzyme for endogenous asparagine…”
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14
STARD4 promotes breast cancer cell malignancy
Published in Oncology reports (01-12-2020)“…Breast cancer (BRCA) is one of the most common malignancies encountered in women worldwide. Lipid metabolism has been found to be involved in cancer…”
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15
MTMR3 is upregulated in patients with breast cancer and regulates proliferation, cell cycle progression and autophagy in breast cancer cells
Published in Oncology reports (01-11-2019)“…As a member of the myotubularin family, myotubularin related protein 3 (MTMR3) has been demonstrated to participate in tumor development, including oral and…”
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16
Nasopharyngeal carcinoma progression is mediated by EBER-triggered inflammation via the RIG-I pathway
Published in Cancer letters (28-05-2015)“…Highlights • We ascertain the correlation between EBER and RIG-I expression from both NPC cell lines and clinical tissues data. • We make it clear that EBERs…”
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17
The Association of R-Loop Binding Proteins Subtypes with CIN Implicates Therapeutic Strategies in Colorectal Cancer
Published in Cancers (15-11-2022)“…Chromosomal instability (CIN) covers approximately 65 to 70% of colorectal cancer patients and plays an essential role in cancer progression. However, the…”
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18
Dual blockage of STAT3 and ERK1/2 eliminates radioresistant GBM cells
Published in Redox biology (01-06-2019)“…Radiotherapy (RT) is the major modality for control of glioblastoma multiforme (GBM), the most aggressive brain tumor in adults with poor prognosis and low…”
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Mast Cell-Induced Lung Injury in Mice Infected with H5N1 Influenza Virus
Published in Journal of Virology (01-03-2012)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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RIG‐I promotes IFN/JAK2 expression and the endoplasmic reticulum stress response to inhibit chemoradiation resistance in nasopharyngeal carcinoma
Published in Cancer medicine (Malden, MA) (01-10-2019)“…RIG‐I is associated with the occurrence and development of many tumors. However, the role of RIG‐I in radiotherapy and chemotherapy in NPC has not been…”
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