Search Results - "Sun, Lu O."

Developmental Heterogeneity of Microglia and Brain Myeloid Cells Revealed by Deep Single-Cell RNA Sequencing by Li, Qingyun, Cheng, Zuolin, Zhou, Lu, Darmanis, Spyros, Neff, Norma F., Okamoto, Jennifer, Gulati, Gunsagar, Bennett, Mariko L., Sun, Lu O., Clarke, Laura E., Marschallinger, Julia, Yu, Guoqiang, Quake, Stephen R., Wyss-Coray, Tony, Barres, Ben A.

“…Microglia are increasingly recognized for their major contributions during brain development and neurodegenerative disease. It is currently unknown whether…”
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Spatiotemporal Control of CNS Myelination by Oligodendrocyte Programmed Cell Death through the TFEB-PUMA Axis by Sun, Lu O., Mulinyawe, Sara B., Collins, Hannah Y., Ibrahim, Adiljan, Li, Qingyun, Simon, David J., Tessier-Lavigne, Marc, Barres, Ben A.

“…Nervous system function depends on proper myelination for insulation and critical trophic support for axons. Myelination is tightly regulated spatially and…”
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Functional Assembly of Accessory Optic System Circuitry Critical for Compensatory Eye Movements by Sun, Lu O., Brady, Colleen M., Cahill, Hugh, Al-Khindi, Timour, Sakuta, Hiraki, Dhande, Onkar S., Noda, Masaharu, Huberman, Andrew D., Nathans, Jeremy, Kolodkin, Alex L.

“…Accurate motion detection requires neural circuitry that compensates for global visual field motion. Select subtypes of retinal ganglion cells perceive image…”
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Distinct oligodendrocyte populations have spatial preference and different responses to spinal cord injury by Floriddia, Elisa M., Lourenço, Tânia, Zhang, Shupei, van Bruggen, David, Hilscher, Markus M., Kukanja, Petra, Gonçalves dos Santos, João P., Altınkök, Müge, Yokota, Chika, Llorens-Bobadilla, Enric, Mulinyawe, Sara B., Grãos, Mário, Sun, Lu O., Frisén, Jonas, Nilsson, Mats, Castelo-Branco, Gonçalo

“…Mature oligodendrocytes (MOLs) show transcriptional heterogeneity, the functional consequences of which are unclear. MOL heterogeneity might correlate with the…”
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On and Off Retinal Circuit Assembly by Divergent Molecular Mechanisms by Sun, Lu O., Jiang, Zheng, Rivlin-Etzion, Michal, Hand, Randal, Brady, Colleen M., Matsuoka, Ryota L., Yau, King-Wai, Feller, Maria B., Kolodkin, Alex L.

“…Direction-selective responses to motion can be to the onset (On) or cessation (Off) of illumination. Here, we show that the transmembrane protein semaphorin 6A…”
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Oligodendrocyte-lineage cell exocytosis and L-type prostaglandin D synthase promote oligodendrocyte development and myelination by Pan, Lin, Trimarco, Amelia, Zhang, Alice J, Fujimori, Ko, Urade, Yoshihiro, Sun, Lu O, Taveggia, Carla, Zhang, Ye

“…In the developing central nervous system, oligodendrocyte precursor cells (OPCs) differentiate into oligodendrocytes, which form myelin around axons…”
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Autophagy collaborates with apoptosis pathways to control oligodendrocyte number by Zhang, Tingxin, Bhambri, Aksheev, Zhang, Yihe, Barbosa, Daniela, Bae, Han-Gyu, Xue, Jumin, Wazir, Sabeen, Mulinyawe, Sara B., Kim, Jun Hee, Sun, Lu O.

“…Oligodendrocytes are the sole myelin-producing cells in the central nervous system. Oligodendrocyte number is tightly controlled across diverse brain regions…”
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Glia Get Neurons in Shape by Sun, Lu O., Barres, Ben A.

“…Glial cells are essential components of the nervous system. In this issue, Singhvi et al. uncover cellular and molecular mechanisms through which C. elegans…”
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A luciferase fragment complementation assay to detect focal adhesion kinase (FAK) signaling events by Estep, Jason A., Sun, Lu O., Riccomagno, Martin M.

“…Integrin Adhesion Complexes (IACs) serve as links between the cytoskeleton and extracellular environment, acting as mechanosensing and signaling hubs. As such,…”
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Guidance-cue control of horizontal cell morphology, lamination, and synapse formation in the mammalian outer retina by Matsuoka, Ryota L, Jiang, Zheng, Samuels, Ivy S, Nguyen-Ba-Charvet, Kim T, Sun, Lu O, Peachey, Neal S, Chédotal, Alain, Yau, King-Wai, Kolodkin, Alex L

“…In the vertebrate retina, neuronal circuitry required for visual perception is organized within specific laminae. Photoreceptors convey external visual…”
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Cas adaptor proteins organize the retinal ganglion cell layer downstream of integrin signaling by Riccomagno, Martin M, Sun, Lu O, Brady, Colleen M, Alexandropoulos, Konstantina, Seo, Sachiko, Kurokawa, Mineo, Kolodkin, Alex L

“…Stratification of retinal neuronal cell bodies and lamination of their processes provide a scaffold upon which neural circuits can be built. However, the…”
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Sema6B, Sema6C, and Sema6D expression and function during mammalian retinal development by Matsuoka, Ryota L, Sun, Lu O, Katayama, Kei-ichi, Yoshida, Yutaka, Kolodkin, Alex L

“…In the vertebrate retina, the formation of neural circuits within discrete laminae is critical for the establishment of retinal visual function. Precise…”
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Dlg5 regulates dendritic spine formation and synaptogenesis by controlling subcellular N-cadherin localization by Wang, Shih-Hsiu J, Celic, Ivana, Choi, Se-Young, Riccomagno, Martin, Wang, Qiang, Sun, Lu O, Mitchell, Sarah P, Vasioukhin, Valera, Huganir, Richard L, Kolodkin, Alex L

“…Most excitatory synapses in the mammalian brain are formed on dendritic spines, and spine density has a profound impact on synaptic transmission, integration,…”
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