Search Results - "Sun, Leina"

Two case reports: EML4-ALK rearrangement large cell neuroendocrine carcinoma and literature review by Chen, Qin, Zhang, Jingjing, Wang, Xuan, Zong, Wenkang, Sun, Leina, Qin, Jianwen, Yin, Yan

“…Anaplastic lymphoma kinase gene (ALK) rearrangement is present in only approximately 5% of non-small cell lung cancers (NSCLCs) and is scarce in LCNEC…”
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Maturation and abundance of tertiary lymphoid structures are associated with the efficacy of neoadjuvant chemoimmunotherapy in resectable non-small cell lung cancer by Sun, Xiaoyan, Liu, Weiran, Sun, Leina, Mo, Huilan, Feng, Yingnan, Wu, Xinyi, Li, Chenguang, Chen, Chen, Li, Jingjing, Xin, Ying, Zhang, Zhenfa, Wang, Changli, Zhang, Bin, Yue, Dongsheng

“…Tertiary lymphoid structures (TLS) existence is correlated with favorable prognosis in many types of cancer including non-small cell lung cancer (NSCLC)…”
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CT‐based radiomics model to predict spread through air space in resectable lung cancer by Gong, Jialin, Yin, Rui, Sun, Leina, Gao, Na, Wang, Xiaofei, Zhang, Lianmin, Zhang, Zhenfa

“…Background Spread through air space (STAS) has been identified as a pathological pattern associated with lung cancer progression. Patients with STAS were…”
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Case Report: Sarcoid-Like Reactions and Tertiary Lymphoid Structures Following Dual Checkpoint Inhibition in a Patient with Early-Stage Lung Adenocarcinoma by Zhao, Xiaoliang, Yue, Dongsheng, Qian, Juanjuan, Zhang, Lei, Song, Jin, Zhang, Bin, Zhang, Chunmei, Sun, Leina, Ma, Yuchen, Zhang, Henghui, Wang, Changli

“…Immune checkpoint inhibitor-induced sarcoid-like reactions and tertiary lymphoid structures (TLSs) are increasingly recognized but rarely reported in the same…”
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Comparison of KRAS and EGFR gene status between primary non-small cell lung cancer and local lymph node metastases: implications for clinical practice by Sun, Leina, Zhang, Qiang, Luan, Huanling, Zhan, Zhongli, Wang, Changli, Sun, Baocun

“…Epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKI) have been widely used for the treatment of non-small cell lung cancer (NSCLC). KRAS and…”
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Comprehensive analyses unveil novel genomic and immunological characteristics of micropapillary pattern in lung adenocarcinoma by Huo, Yansong, Sun, Leina, Yuan, Jie, Zhang, Hua, Zhang, Zhenfa, Zhang, Lianmin, Huang, Wuhao, Sun, Xiaoyan, Tang, Zhe, Feng, Yingnan, Mo, Huilan, Yang, Zuoquan, Zhang, Chao, Yu, Zicheng, Yue, Dongsheng, Zhang, Bin, Wang, Changli

“…Lung adenocarcinoma (LUAD) usually contains heterogeneous histological subtypes, among which the micropapillary (MIP) subtype was associated with poor…”
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Effectiveness of alectinib and osimertinib in a brain metastasized lung adenocarcinoma patient with concurrent EGFR mutations and DCTN1‐ALK fusion by Yin, Qiang, Guo, Taiyan, Zhou, Yangyang, Sun, Leina, Meng, Maobin, Ma, Li, Wang, Xiaoguang

“…The echinoderm microtubule associated protein‐like 4 gene (EML4) encodes the predominant anaplastic lymphoma kinase (ALK) fusion partner in non‐small‐cell lung…”
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Is MPP a good prognostic factor in stage III lung adenocarcinoma with EGFR exon 19 mutation? by Zhang, Tian, Wang, Jing, Su, Yanjun, Chen, Xi, Yan, Qingna, Li, Qi, Sun, Leina, Wang, Yuwen, Er, Puchun, Pang, Qingsong, Wang, Ping

“…Epidermal growth factor receptor (EGFR) is a transmembrane glycoprotein encoded by a gene located in the short arm of chromosome 7. This study aimed to…”
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A Case of Simultaneously Diagnosed Lung Adenocarcinoma and Endobronchial Inflammatory Myofibroblastic Tumor with Two Distinct Types of ALK Translocation by Zhao, Shikang, Liu, Wei, Li, Shuo, Shi, Tao, Chen, Qiusong, Li, Qi, Sun, Leina, Ren, Dian, Song, Zuoqing, Huang, Chun, Xu, Song

“…A 61-year-old male patient was simultaneously diagnosed with lung adenocarcinoma and inflammatory myofibroblastic tumor (IMT). The lung adenocarcinoma and IMT…”
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A nomogram-based immune-serum scoring system predicts overall survival in patients with lung adenocarcinoma by Huang, Qiujuan, Qu, Tongyuan, Qi, Lisha, Liu, Changxu, Guo, Yuhong, Guo, Qianru, Li, Guangning, Wang, Yalei, Zhang, Wenshuai, Zhao, Wei, Ren, Danyang, Sun, Leina, Wang, Shengguang, Meng, Bin, Sun, Baocun, Zhang, Bin, Ma, Wenjuan, Cao, Wenfeng

“…The immunoscore, which is used to quantify immune infiltrates, has greater relative prognostic value than tumor, node, and metastasis (TNM) stage and might…”
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Real‐world data on ALK rearrangement test in Chinese advanced non‐small cell lung cancer (RATICAL): a nationwide multicenter retrospective study by Li, Lin, Li, Wencai, Wu, Chunyan, Xi, Yanfeng, Guo, Lei, Ji, Yuan, Jiang, Lili, Li, Ji, Yun, Jingping, Chen, Gang, Li, Yuan, Liu, Yueping, Mu, Dianbin, Han, Yuchen, Sun, Leina, Xia, Qingxin, Teng, Xiaodong, Che, Nanying, Wu, Wei, Qiu, Xueshan, Liu, Chao, Yan, Xiaochu, Li, Daiqiang, Zhang, Zhihong, Wang, Zhe, Li, Yujun, Wang, Zheng, Guo, Lingchuan, Nie, Xiu, Geng, Jingshu, Zhou, Jianhua, Ying, Jianming

“…Background Anaplastic lymphoma kinase (ALK) test in advanced non‐small cell lung cancer (NSCLC) can help physicians provide target therapies for patients…”
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Study on the Biological Function of Abemecilib in Inhibiting the Proliferation, Invasion and
Migration of Small Cell Lung Cancer with High c-Myc Expression by Guo, Jingjing, Mu, Di, Yu, Wenwen, Sun, Leina, Zhang, Jiali, Ren, Xiubao, Han, Ying

“…Small cell lung cancer (SCLC) with high c-Myc expression is prone to relapse and metastasis, leading to extremely low survival rate. Cyclin-dependent kinases 4…”
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Meta-analysis of nifedipine and enalapril combination therapy for hypertensive patients with coronary heart disease by Wang, Kun, Ma, Wenchao, Sun, Leina, Su, Fangcheng

“…Background: Numerous clinical studies have demonstrated that the therapeutic efficacy of combining nifedipine and enalapril in treating hypertension with…”
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MicroRNA‐130b targets PTEN to induce resistance to cisplatin in lung cancer cells by activating Wnt/β‐catenin pathway by Zhang, Qiang, Zhang, Bin, Sun, Leina, Yan, Qingna, Zhang, Yu, Zhang, Zhenfa, Su, Yanjun, Wang, Changli

“…More and more studies indicate the relevance of miRNAs in inducing certain drug resistance. Our study aimed to investigate whether microRNA‐130b‐3p (miR‐130b)…”
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Cisplatin resistance in lung cancer is mediated by MACC1 expression through PI3K/AKT signaling pathway activation by Zhang, Qiang, Zhang, Bin, Sun, Leina, Yan, Qingna, Zhang, Yu, Zhang, Zhenfa, Su, Yanjun, Wang, Changli

“…Abstract One of the major obstacles hindering the treatment of lung cancer (LC) is chemoresistance; however, its mechanism remains unclear. The overexpression…”
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A study of ALK-positive pulmonary squamous-cell carcinoma: From diagnostic methodologies to clinical efficacy by Wang, Haiyue, Sun, Leina, Sang, Yaxiong, Yang, Xin, Tian, Guangming, Wang, Ziping, Fang, Jian, Sun, Wei, Zhou, Lixin, Jia, Ling, Tsao, Ming-Sound, Shi, Huaiyin, Lin, Dongmei

“…•Three testing methodologies (IHC, FISH, NGS) for ALK gene status in LSCC are compared•A realistic prevalence of the ALK rearrangement rate (0.17%) in LSCC is…”
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Abemaciclib抑制c-Myc高表达小细胞肺癌增殖、侵袭和迁移的生物学功能的研究 by GUO, Jingjing, MU, Di, YU, Wenwen, SUN, Leina, ZHANG, Jiali, REN, Xiubao, HAN, Ying

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Platelet-lymphocyte ratio is an independent prognostic factor in patients with ALK-positive non-small-cell lung cancer by Han, Ying, Wang, Jing, Hong, Liping, Sun, Leina, Zhuang, Hongqing, Sun, Bingsheng, Wang, Hua, Zhang, Xinwei, Ren, Xiubao

“…As the prognostic value of the neutrophil-lymphocyte ratio (NLR) and platelet-lymphocyte ratio (PLR) is unclear in patients with ALK-positive non-small-cell…”
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Correlation of Activated STAT3 Expression with Clinicopathologic Features in Lung Adenocarcinoma and Squamous Cell Carcinoma by Jiang, Richeng, Jin, Ziliang, Liu, Zhujun, Sun, Leina, Wang, Liuchun, Li, Kai

“…Background and Objective: Signal transducer and activator of transcription (STAT) 3, a member of the STAT family of transcription factors in the Janus kinase…”
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Correlation of Activated STAT3 Expression with Clinicopathologic Features in Lung Adenocarcinoma and Squamous Cell Carcinoma by Jiang, Richeng, Jin, Ziliang, Liu, Zhujun, Sun, Leina, Wang, Liuchun, Li, Kai

“…Background and Objective: Signal transducer and activator of transcription (STAT) 3, a member of the STAT family of transcription factors in the Janus kinase…”
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