Search Results - "Sun, Junran"

Comprehensive assessment of the impact of intravitreal faricimab on retinal diseases: A systematic review, meta-analysis, and trial sequential analysis by Zhang, Guanran, Wen, Xin, Li, Yanrong, Sun, Junran, Jia, Huixun, Sun, Xiaodong

“…Faricimab stands as the inaugural and sole bispecific antibody approved by the US Food and Drug Administration (FDA) for intravitreal injection. Nonetheless,…”
Get full text

Dynamic changes in macrophage morphology during the progression of choroidal neovascularization in a laser-induced choroidal neovascularization mouse model by Xu, Nana, Sun, Tao, Wang, Yulan, Tong, Xiaowei, Lu, Shiheng, Yang, Fan, Wang, Jing, Bo, Qiyu, Sun, Junran, Sun, Xiaodong

“…Abstract Background Neovascular age-related macular degeneration (AMD) is responsible for the majority of severe vision loss cases and is mainly caused by…”
Get full text

Association between previous cataract surgery and cognition among middle-aged and older Chinese: the China health and retirement longitudinal study (CHARLS) by Zhao, Xiaohuan, Wei, Kunchen, Sun, Junran, Chen, Jieqiong, Wang, Yimin, Chen, Yuhong, Zhu, Xinyue, Sun, Xiaodong, Li, Tong, Zhou, Minwen

“…Cataract is the primary cause of blindness globally, and surgery offers the only method by which to remove cataracts. We aimed to examine whether previous…”
Get full text

Cooperation of Rel family members in regulating Aβ1-40-mediated pro-inflammatory cytokine secretion by retinal pigment epithelial cells by Sun, Junran, Huang, Peirong, Liang, Jian, Li, Jie, Shen, Mengxi, She, Xiangjun, Feng, Yiji, Luo, Xueting, Liu, Te, Sun, Xiaodong

“…Amyloid-beta (A β ) is a hallmark component of age-related macular degeneration (AMD), which induces secretion of pro-inflammatory cytokines from retinal…”
Get full text

Spectrum of retinal microvascular ischemia in patients with COVID-19 based on multimodal imaging by Zhang, Min, Sun, Junran, Wang, Chanchan, Su, Li, Chen, Jieqiong, Wang, Yimin, Sun, Xiaodong, Gong, Yuanyuan, Yu, Suqin

“…To describe and evaluate the multimodal imaging findings in retinal microvascular ischemia associated with COVID-19 infection. Patients with COVID-19…”
Get full text

Choroidal pericytes promote subretinal fibrosis after experimental photocoagulation by Luo, Xueting, Yang, Shiqi, Liang, Jian, Zhai, Yuanqi, Shen, Mengxi, Sun, Junran, Feng, Yiji, Lu, Xinmin, Zhu, Hong, Wang, Fenghua, Sun, Xiaodong

“…Subretinal fibrosis results in local destruction of retinal structures and permanent vision loss, representing the end stage of neovascular age-related macular…”
Get full text

Functional evaluation with microperimetry in large idiopathic macular holes treated by a free internal limiting membrane flap tamponade technique by Huang, Peirong, Wang, Hong, Chen, Fenge, Chen, Jieqiong, Hu, Yifan, Sun, Junran, Feng, Jingyang, Zhu, Hong

“…Free internal limiting membrane (ILM) flap tamponade technique is an alternative choice for treating large idiopathic macular holes (IMHs). However, the…”
Get full text

The association between obesity and glaucoma in older adults: evidence from the China Health and Retirement Longitudinal Study by Zhao, Xiaohuan, Bo, Qiyu, Sun, Junran, Chen, Jieqiong, Li, Tong, Huang, Xiaoxu, Zhou, Minwen, Wang, Jing, Liu, Wenjia, Sun, Xiaodong

“…This study evaluated the association between obesity and glaucoma in middle-aged and older people. A population-based retrospective cohort study was conducted…”
Get full text

Unilateral Lipemic Aqueous by Sun, Junran, Gong, Yuanyuan, Yu, Suqin

Get full text

PFKFB3 knockdown attenuates Amyloid β-Induced microglial activation and retinal pigment epithelium disorders in mice by Wang, Yusong, Han, Siyang, Chen, Jieqiong, Sun, Junran, Sun, Xiaodong

“…•Intravitreal injection of oligomeric Amyloid β can cause retinal inflammatory microenvironment.•Inflammatory cytokines are reduced by activated microglia in…”
Get full text

Safety of Receiving Anti-Vascular Endothelial Growth Factor Intravitreal Injection in Office-Based vs Operating Room Settings: A Meta-analysis by Li, Tong, Sun, Junran, Min, Jingyu, Zhou, Shuangwen, Zhu, Xiaolin, Jia, Huixun, Sun, Xiaodong

“…Compared with the operating room (OR), office-based intravitreal injection (IVI) is considered a more cost-effective and convenient approach, yet clinical…”
Get more information

TRIM31 inhibits NLRP3 inflammasome and pyroptosis of retinal pigment epithelial cells through ubiquitination of NLRP3 by Huang, Peirong, Liu, Wenjia, Chen, Jieqiong, Hu, Yifan, Wang, Yuwei, Sun, Junran, Feng, Jingyang

“…NOD‐like receptor protein 3 (NLRP3) is associated with age‐related macular degeneration (AMD). Retinal pigment epithelial (RPE) cells serve as the immune…”
Get full text

Prevalence and Risk Factors of Glaucoma Among Chinese People From the China Health and Retirement Longitudinal Study by Sun, Junran, Li, Tong, Zhao, Xiaohuan, Lu, Bing, Chen, Jieqiong, Liu, Wenjia, Zhou, Minwen, Sun, Xiaodong

“…Précis: This study demonstrated the prevalence of self-reported glaucoma and its strong association with preexisting systemic chronic diseases in China using…”
Get full text

Clinical and Molecular Characterization of AIPL1-Associated Leber Congenital Amaurosis/Early-Onset Severe Retinal Dystrophy by Zhang, Quan, Sun, Junran, Liu, Zishi, Wang, Hong, Zhou, Hao, Liu, Wenjia, Jia, Huixun, Li, Ningdong, Li, Tong, Wang, Fenghua, Sun, Xiaodong

“…This study aimed to characterize the clinical features, genetic findings, and genotype-phenotype correlations of patients with Leber congenital amaurosis (LCA)…”
Get full text

MicroRNA Expression Patterns Involved in Amyloid Beta-Induced Retinal Degeneration by Huang, Peirong, Sun, Junran, Wang, Fenghua, Luo, Xueting, Feng, Jingyang, Gu, Qing, Liu, Te, Sun, Xiaodong

“…Dry age-related macular degeneration (AMD) is characterized by the accumulation of drusen under Bruch's membrane, and amyloid beta (Aβ) is speculated to be one…”
Get full text

Fat mass and obesity-associated protein alleviates Aβ 1-40 induced retinal pigment epithelial cells degeneration via PKA/CREB signaling pathway by Hu, Yifan, Chen, Jieqiong, Wang, Yuwei, Sun, Junran, Huang, Peirong, Feng, Jingyang, Liu, Te, Sun, Xiaodong

“…Amyloid-β (Aβ) is thought to be a critical pathologic factor of retinal pigment epithelium (RPE) degeneration in age-related macular degeneration (AMD). Aβ…”
Get full text

Fat mass and obesity‐associated protein alleviates Aβ1–40 induced retinal pigment epithelial cells degeneration via PKA/CREB signaling pathway by Hu, Yifan, Chen, Jieqiong, Wang, Yuwei, Sun, Junran, Huang, Peirong, Feng, Jingyang, Liu, Te, Sun, Xiaodong

“…Amyloid‐β (Aβ) is thought to be a critical pathologic factor of retinal pigment epithelium (RPE) degeneration in age‐related macular degeneration (AMD). Aβ…”
Get full text

Prevalence and Risk Factors of Glaucoma Among Chinese People.From the China Health and Retirement Longitudinal Study by Sun, Junran, Li, Tong, Zhao, Xiaohuan, Lu, Bing, Chen, Jieqiong, Liu, Wenjia, Zhou, Minwen, Sun, Xiaodong

Get full text

GENETIC FACTORS AND CHARACTERISTICS ON SPECTRAL-DOMAIN OPTICAL COHERENCE TOMOGRAPHY ARE ASSOCIATED WITH CHOROIDAL THICKNESS IN ABCA4 -RELATED RETINOPATHY by Wang, Yimin, Chen, Jieqiong, Zhang, Min, Yu, Suqin, Gong, Yuanyuan, Lin, Feng, Wu, Yidong, Liu, Wenjia, Sun, Junran, Li, Tong, Sun, Xiaodong

“…To investigate the possible correlation factors of choroidal thickness in ABCA4 -related retinopathy. A total of 66 patients were included in the cohort. It is…”
Get full text

A Novel Bispecific Fusion Protein Targeting C3b/C4b and VEGF in Patients With nAMD: A Randomized, Open-Label, Phase 1b Study by Jia, Huixun, Li, Tong, Sun, Junran, Gong, Yuanyuan, Liu, Haiyun, Wang, Hong, Chen, Jieqiong, Liu, Wenjia, Lu, Shujie, Feng, Liqi, Wan, Qiuchen, Qian, Lei, Wang, Fenghua, Liu, Xiaoling, Sun, Xiaodong

“…To evaluate the safety, tolerability, and efficacy of efdamrofusp alfa in patients with neovascular age-related macular degeneration (nAMD). Prospective…”
Get full text