Search Results - "Sun, Huaiyu"
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Poly-Small Ubiquitin-like Modifier (PolySUMO)-binding Proteins Identified through a String Search
Published in The Journal of biological chemistry (07-12-2012)“…Polysumoylation is a crucial cellular response to stresses against genomic integrity or proteostasis. Like the small ubiquitin-like modifier (SUMO)-targeted…”
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Suppression of JNK pathway protects neurons from oxidative injury via attenuating parthanatos in glutamate-treated HT22 neurons
Published in Scientific reports (28-10-2024)“…Oxidative stress causes diverse neurological disorders. Parthanatos is a type of programmed cell death, characterised by strong activation of poly (ADP-ribose)…”
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Conserved function of RNF4 family proteins in eukaryotes: targeting a ubiquitin ligase to SUMOylated proteins
Published in The EMBO journal (19-09-2007)“…The function of small ubiquitin‐like modifier (SUMO)‐binding proteins is key to understanding how SUMOylation regulates cellular processes. We identified two…”
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4
Inflammatory cytokines and stroke and its subtypes: a genetic correlation and two-sample Mendelian randomization study
Published in Frontiers in molecular neuroscience (28-11-2023)“…The causal relationship between inflammatory factors and stroke subtypes remains unclear. This study aimed to analyze the causal relationship between 41…”
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The pathogenesis of blepharospasm
Published in Frontiers in neurology (11-01-2024)“…Blepharospasm is a focal dystonia characterized by involuntary tetanic contractions of the orbicularis oculi muscle, which can lead to functional blindness and…”
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The JAK-STAT Signaling Pathway in Epilepsy
Published in Current neuropharmacology (01-01-2023)“…Epilepsy is defined as spontaneous recurrent seizures in the brain. There is increasing evidence that inflammatory mediators and immune cells are involved in…”
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Exploration of the causal associations between circulating inflammatory proteins, immune cells, and neuromyelitis optica spectrum disorder: a bidirectional Mendelian randomization study and mediation analysis
Published in Frontiers in aging neuroscience (26-04-2024)“…An increasing body of research has demonstrated a robust correlation between circulating inflammatory proteins and neuromyelitis optica spectrum disorders…”
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Endoscopic 1½-transseptal approach for pituitary surgery
Published in Frontiers in oncology (12-01-2023)“…We previously introduced the one-and-a-half (1½) nostril endoscopic transsphenoidal approach (OETA) to reduce the damage to the nasal structures. Here, we…”
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Are anti-glutamic acid decarboxylase 65-kDa isoform antibodies related to diabetes or brain tumor?
Published in European journal of medical research (06-04-2022)“…Antibodies against the 65-kDa isoform of glutamic acid decarboxylase (GAD65) are biomarkers of autoimmune disorders and are more common in non-neurological…”
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NKCC1 involvement in the epithelial-to-mesenchymal transition is a prognostic biomarker in gliomas
Published in PeerJ (San Francisco, CA) (16-03-2020)“…Gliomas are the most prevalent type of intracranial tumors. NKCC1 is an important regulator in tumor cell volume. We noticed that abnormally high NKCC1…”
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RING domain dimerization is essential for RNF4 function
Published in Biochemical journal (01-10-2010)“…RNF4 [RING (really interesting new gene) finger protein 4] family ubiquitin ligases are RING E3 ligases that regulate the homoeostasis of SUMOylated proteins…”
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Contribution of maternal copy number variations to false‐positive fetal trisomies detected by noninvasive prenatal testing
Published in Prenatal diagnosis (01-04-2017)“…Objective The aim of the study was to determine the contribution and significance of maternal copy number variations (CNVs) to false‐positive noninvasive…”
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Anterior Clinoidal Meningiomas: Meningeal Anatomical Considerations and Surgical Implications
Published in Frontiers in oncology (25-05-2020)“…Objective: Surgical removal of anterior clinoidal meningiomas (ACMs) remains a challenge because of its complicated relationship with surrounding meninges,…”
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14
Tube Is an IRAK-4 Homolog in a Toll Pathway Adapted for Development and Immunity
Published in Journal of innate immunity (01-01-2009)“…Acting through the Pelle and IRAK family of protein kinases, Toll receptors mediate innate immune responses in animals ranging from insects to humans. In…”
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The protein kinase Pak3 positively regulates Raf-1 activity through phosphorylation of serine 338
Published in Nature (London) (12-11-1998)“…The pathway involving the signalling protein p21Ras propagates a range of extracellular signals from receptors on the cell membrane to the cytoplasm and…”
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16
A Heterotrimeric Death Domain Complex in Toll Signaling
Published in Proceedings of the National Academy of Sciences - PNAS (01-10-2002)“…Signaling from the transmembrane receptor Toll to Rel-related transcription factors regulates dorsoventral patterning of the Drosophila embryo, as well as…”
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Regulated assembly of the Toll signaling complex drives Drosophila dorsoventral patterning
Published in The EMBO journal (14-01-2004)“…In Drosophila, the Toll pathway establishes the embryonic dorsoventral axis and triggers innate immune responses to infection. The transmembrane receptor Toll…”
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Regulation of the protein kinase Raf-1 by oncogenic Ras through phosphatidylinositol 3-kinase, Cdc42/Rac and Pak
Published in Current biology (09-03-2000)“…Activation of the protein kinase Raf-1 is a complex process involving association with the GTP-bound form of Ras (Ras–GTP), membrane translocation and both…”
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Association of oxidative balance score with epilepsy and moderate to severe depression: Insights from the NHANES study
Published in Journal of affective disorders (15-10-2024)“…Depression is a significant public health issue, closely associated with epilepsy and oxidative stress (OS). This study aims to explore the level of OS in…”
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Pressure Fluctuation in the Submerged Circulative Impinging Stream Reactor
Published in Chinese journal of chemical engineering (01-08-2006)Get full text
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