Search Results - "Sun, Hongyin"

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  1. 1

    Potent BRD4 inhibitor suppresses cancer cell-macrophage interaction by Yin, Mingzhu, Guo, Ying, Hu, Rui, Cai, Wesley L., Li, Yao, Pei, Shiyao, Sun, Hongyin, Peng, Cong, Li, Jiali, Ye, Rui, Yang, Qiaohong, Wang, Nenghui, Tao, Yongguang, Chen, Xiang, Yan, Qin

    Published in Nature communications (14-04-2020)
    “…Small molecule inhibitor of the bromodomain and extraterminal domain (BET) family proteins is a promising option for cancer treatment. However, current BET…”
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    Journal Article
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    Discovery of WD-890: A novel allosteric TYK2 inhibitor for the treatment of multiple autoimmune diseases by Fang, Zhiqin, Sun, Hongyin, Wang, Yutong, Sun, Zhenliang, Yin, Mingzhu

    Published in Biomedicine & pharmacotherapy (01-11-2023)
    “…Tyrosine kinase 2 (TYK2) as a member of Janus kinase (JAK) family, mainly mediates the signaling of type I interferons (IFN), interleukin-12 (IL-12) and…”
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    Journal Article
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    eEF2K promotes PD-L1 stabilization through inactivating GSK3β in melanoma by Chen, Xisha, Wang, Kuansong, Jiang, Shilong, Sun, Hongyin, Che, Xuanling, Zhang, Minghui, He, Jiaying, Wen, Ying, Liao, Mengting, Li, Xiangling, Zhou, Xiaoming, Song, Jianxun, Ren, Xingcong, Yi, Wenjun, Yang, Jinming, Chen, Xiang, Yin, Mingzhu, Cheng, Yan

    Published in Journal for immunotherapy of cancer (01-03-2022)
    “…Immune checkpoint blockade (ICB) targeting programmed death ligand-1 (PD-L1)/programmed cell death protein-1 (PD-1) pathway has become an attractive strategy…”
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    Journal Article
  6. 6

    A Distributed SoC Balancing Control Method for Series-type Energy Storage System in Grid-connected Mode by Duo, Zhang, Hongyin, Sun, Shimiao, Chen, Guangze, Shi, Hui, Wang

    “…Energy storage system (ESS) equipped with power electronics plays an essential role in renewable energy integration. Series-type energy storage system (SESS)…”
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    Conference Proceeding
  7. 7

    Interleukin-1 receptor antagonist improves normoglycemia and insulin sensitivity in diabetic Goto-Kakizaki-rats by Akash, Muhammad Sajid Hamid, Rehman, Kanwal, Sun, Hongyin, Chen, Shuqing

    Published in European journal of pharmacology (15-02-2013)
    “…Type 2 diabetes mellitus has been considered as an auto-inflammatory syndrome. Interleukin-1 receptor antagonist (IL-1Ra) has attained considerable attention…”
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    Journal Article
  8. 8

    Tumour vasculature at single-cell resolution by Pan, Xu, Li, Xin, Dong, Liang, Liu, Teng, Zhang, Min, Zhang, Lining, Zhang, Xiyuan, Huang, Lingjuan, Shi, Wensheng, Sun, Hongyin, Fang, Zhaoyu, Sun, Jie, Huang, Yaoxuan, Shao, Hua, Wang, Yeqi, Yin, Mingzhu

    Published in Nature (London) (08-08-2024)
    “…Tumours can obtain nutrients and oxygen required to progress and metastasize through the blood supply 1 . Inducing angiogenesis involves the sprouting of…”
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    Journal Article
  9. 9

    BRD4 inhibitor suppresses melanoma metastasis via the SPINK6/EGFR-EphA2 pathway by Hu, Rui, Li, Yao, Guo, Ying, Li, Xin, Du, Songtao, Liao, Mengting, Hou, Huihui, Sun, Hongyin, Zhao, Shuang, Su, Juan, Chen, Xiang, Yin, Mingzhu

    Published in Pharmacological research (01-01-2023)
    “…BET inhibition or BRD4 depletion is a promising and attractive therapy for metastatic melanoma; however, the mechanism is still unclear. Here, we indicated…”
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    Journal Article
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    Combined BET and MEK Inhibition synergistically suppresses melanoma by targeting YAP1 by Hu, Rui, Hou, Huihui, Li, Yao, Zhang, Minghui, Li, Xin, Chen, Yanzhong, Guo, Ying, Sun, Hongyin, Zhao, Shuang, Liao, Mengting, Cao, Dongsheng, Yan, Qin, Chen, Xiang, Yin, Mingzhu

    Published in Theranostics (2024)
    “…The response rate to the MEK inhibitor trametinib in BRAF-mutated melanoma patients is less than 30%, and drug resistance develops rapidly, but the mechanism…”
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    Journal Article
  12. 12

    Speech enhancement using orthogonal matching pursuit algorithm by Hongwu Yang, Dongliang Hao, Hongyin Sun, Yitong Liu

    “…This paper proposes a novel approach for speech enhancement based on compressed sensing (CS) theory. Each frame of noisy speech signal is sparsified firstly by…”
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    Conference Proceeding