Search Results - "Sun, Guogui"
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DNA methylation-mediated repression of exosomal miR-652-5p expression promotes oesophageal squamous cell carcinoma aggressiveness by targeting PARG and VEGF pathways
Published in PLoS genetics (01-04-2020)“…Exosomal microRNAs (miRNAs) have been recently shown to play vital regulatory and communication roles in cancers. In this study, we showed that the expression…”
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2
Application status and future prospects of the PDX model in lung cancer
Published in Frontiers in oncology (24-03-2023)“…Lung cancer is one of the most prevalent, fatal, and highly heterogeneous diseases that, seriously threaten human health. Lung cancer is primarily caused by…”
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3
miR-3607-3p suppresses non-small cell lung cancer (NSCLC) by targeting TGFBR1 and CCNE2
Published in PLoS genetics (01-12-2018)“…Accumulating evidence indicates that miRNAs can be promising diagnostic and/or prognostic markers for various cancers. In this study, we identified a novel…”
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4
MiR-423-5p in brain metastasis: potential role in diagnostics and molecular biology
Published in Cell death & disease (17-09-2018)“…During the last several years, a growing number of studies have shown that microRNAs (miRNAs) participate in cancer metastasis. Brain metastasis (BM) is a…”
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Molecular predictors of brain metastasis-related microRNAs in lung adenocarcinoma
Published in PLoS genetics (01-02-2019)“…Brain metastasis (BM) is a major complication of lung adenocarcinoma (LAD). An investigation of the pathogenic mechanisms of BM, as well as the identification…”
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6
The NR_109/FUBP1/c-Myc axis regulates TAM polarization and remodels the tumor microenvironment to promote cancer development
Published in Journal for immunotherapy of cancer (01-05-2023)“…BackgroundTumor-associated macrophages (TAMs) are a major component of the tumor microenvironment (TME) and exert an important role in tumor progression. Due…”
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7
DNA Methylation-Mediated Repression of miR-886-3p Predicts Poor Outcome of Human Small Cell Lung Cancer
Published in Cancer research (Chicago, Ill.) (01-06-2013)“…Small cell lung cancer (SCLC) is one of the most aggressive types of cancer, yet the pathologic mechanisms underlying its devastating clinical outcome remain…”
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8
Identification of prognosis-related lncRNAs and cell validation in lung squamous cell carcinoma based on TCGA data
Published in Frontiers in oncology (25-10-2023)“…Objective To discern long non-coding RNAs (lncRNAs) with prognostic relevance in the context of lung squamous cell carcinoma (LUSC), we intend to predict…”
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9
Efficacy of radiomics model based on the concept of gross tumor volume and clinical target volume in predicting occult lymph node metastasis in non-small cell lung cancer
Published in Frontiers in oncology (24-05-2023)“…This study aimed to establish a predictive model for occult lymph node metastasis (LNM) in patients with clinical stage I-A non-small cell lung cancer (NSCLC)…”
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10
Functional Significance and Therapeutic Potential of miRNA-20b-5p in Esophageal Squamous Cell Carcinoma
Published in Molecular therapy. Nucleic acids (04-09-2020)“…Novel therapies tailored to the molecular composition mechanism of esophageal squamous cell carcinoma (ESCC) are needed to improve patient survival. miR-20b-5p…”
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Safety and efficacy of apatinib in patients with advanced gastric or gastroesophageal junction adenocarcinoma after the failure of two or more lines of chemotherapy (AHEAD): a prospective, single-arm, multicenter, phase IV study
Published in BMC medicine (05-05-2023)“…Apatinib, a highly selective VEGFR2 inhibitor, significantly improved efficacy versus placebo as a third- and later-line treatment for advanced gastric cancer…”
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12
Correction: Molecular predictors of brain metastasis-related microRNAs in lung adenocarcinoma
Published in PLoS genetics (14-10-2020)“…[This corrects the article DOI: 10.1371/journal.pgen.1007888.]…”
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13
Arsenic nano complex induced degradation of YAP sensitized ESCC cancer cells to radiation and chemotherapy
Published in Cell & bioscience (22-12-2020)“…Increased reactive oxygen species (ROS) production by arsenic treatment in solid tumors showed to be effective to sensitize cancer cells to chemotherapies…”
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14
Electromagnetic interactions in regulations of cell behaviors and morphogenesis
Published in Frontiers in cell and developmental biology (19-10-2022)“…Emerging evidence indicates that the cellular electromagnetic field regulates the fundamental physics of cell biology. The electromagnetic oscillations and…”
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Correction to: Arsenic nano complex induced degradation of YAP sensitized ESCC cancer cells to radiation and chemotherapy
Published in Cell & bioscience (19-01-2021)“…An amendment to this paper has been published and can be accessed via the original article…”
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16
Isoliquiritigenin Modulates the Effect of LINC01503 on Lung Squamous Carcinoma Cells
Published in Zhongguo fei ai za zhi (20-08-2024)“…Isoliquiritigenin (ISL) is an important pharmacological constituent of Glycyrrhiza glabra, which possesses a range of physiological and pharmacological…”
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Integrated machine learning to predict the prognosis of lung adenocarcinoma patients based on SARS ‐ COV ‐2 and lung adenocarcinoma crosstalk genes
Published in Cancer science (03-11-2024)“…Abstract Viruses are widely recognized to be intricately associated with both solid and hematological malignancies in humans. The primary goal of this research…”
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18
One-step algorithm for fast-track localization and multi-category classification of histological subtypes in lung cancer
Published in European journal of radiology (01-09-2022)“…Accumulated evidence has proven that computer-derived features from computed tomography (CT) through radiomics and deep learning technologies can identify…”
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19
Pb induces ferroptosis in choroid plexus epithelial cells via Fe metabolism
Published in Neurotoxicology (Park Forest South) (01-03-2023)“…Pb can enhance blood-cerebrospinal fluid barrier (BCSFB) permeability and accumulate in brain tissue, leading to central nervous system (CNS) dysfunction…”
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Proteasome-Independent Protein Knockdown by Small-Molecule Inhibitor for the Undruggable Lung Adenocarcinoma
Published in Journal of the American Chemical Society (20-11-2019)“…Therapeutic target identification and corresponding drug development is a demanding task for the treatment of lung adenocarcinoma, especially the most…”
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