Search Results - "Sun, Chun Xiang"
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Tissue‐specific murine neutrophil activation states in health and inflammation
Published in Journal of leukocyte biology (01-07-2021)“…Neutrophils are quickly recruited to tissues in response to proinflammatory cues; however, little is known about tissue neutrophil phenotypes in health. We…”
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The effect of pamidronate delivery in bisphosphonate-naïve patients on neutrophil chemotaxis and oxidative burst
Published in Scientific reports (27-10-2020)“…The pathogenesis of medication-related osteonecrosis of the jaw (MRONJ), a morbid condition associated with bisphosphonate administration, has not been fully…”
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Rac1 and Rac2 differentially regulate actin free barbed end formation downstream of the fMLP receptor
Published in The Journal of cell biology (22-10-2007)“…Actin assembly at the leading edge of migrating cells depends on the availability of high-affinity free barbed ends (FBE) that drive actin filament elongation…”
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Treponema denticola major outer sheath protein impairs the cellular phosphoinositide balance that regulates neutrophil chemotaxis
Published in PloS one (03-06-2013)“…The major outer sheath protein (Msp) of Treponema denticola inhibits neutrophil polarization and directed chemotaxis together with actin dynamics in vitro in…”
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Global analysis of neutrophil responses to Neisseria gonorrhoeae reveals a self-propagating inflammatory program
Published in PLoS pathogens (01-09-2014)“…An overwhelming neutrophil-driven response causes both acute symptoms and the lasting sequelae that result from infection with Neisseria gonorrhoeae…”
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Rac1 is the small GTPase responsible for regulating the neutrophil chemotaxis compass
Published in Blood (01-12-2004)“…Although both of the small Rho guanosine triphosphatases (GTPases) Rac1 and Rac2 have been demonstrated to play a role in chemotaxis, the precise and possible…”
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The axonal repellent, Slit2, inhibits directional migration of circulating neutrophils
Published in Journal of leukocyte biology (01-12-2009)“…Slit2, a potentially powerful anti‐inflammatory agent, inhibits polarization and chemotaxis, but not random movement, of primary neutrophils towards diverse…”
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Timing of neutrophil tissue repopulation predicts restoration of innate immune protection in a murine bone marrow transplantation model
Published in Blood (15-10-2006)“…It has been suggested that neutrophil tissue repopulation following bone marrow transplantation (BMT) serves as an earlier and more relevant marker of…”
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9
major outer sheath protein of Treponema denticola selectively inhibits Rac1 activation in murine neutrophils
Published in Cellular microbiology (01-02-2008)“…Treponema denticola major outer sheath protein (Msp) inhibits neutrophil chemotaxis in vitro, but key regulatory mechanisms have not been identified. Because…”
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The role of Rac1 and Rac2 in bacterial killing
Published in Cellular Immunology (01-06-2005)“…The small Rho guanosine triphosphatases (GTPases) Rac1 and Rac2 have distinct roles in regulating neutrophil chemotaxis; however, little is known about their…”
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11
Modulation of Human Neutrophil Functions In Vitro by Treponema denticola Major Outer Sheath Protein
Published in Infection and Immunity (01-03-2006)“…In this study of human polymorphonuclear leukocytes (PMNs), pretreatment with Treponema denticola major outer sheath protein (Msp) inhibited…”
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Curcumin attenuates high glucose-induced podocyte apoptosis by regulating functional connections between caveolin-1 phosphorylation and ROS
Published in Acta pharmacologica Sinica (01-05-2016)“…Aim: Caveolin-1 (cav-1) is a major multifunctional scaffolding protein of caveolae. Cav-1 is primarily expressed in mesangial cells, renal proximal tubule…”
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The Role of PIKfyve in the Neutrophil Innate Immune Response
Published in The FASEB journal (01-04-2015)“…Abstract only Phosphoinositides are lipid signals that help control leukocyte function including phagocytosis, phagosome maturation and chemotaxis. For…”
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Synchronizing Uncertain Chaotic Systems with Neural Network Compensation
Published in 2012 International Conference on Computer Science and Service System (01-08-2012)“…This paper investigates the control problem of synchronize uncertain nonlinear systems by means of adaptive neural network control. A robust adaptive observer…”
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Conference Proceeding -
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Global Analysis of Neutrophil Responses to Neisseria gonorrhoeae Reveals a Self-Propagating Inflammatory Program: e1004341
Published in PLoS pathogens (01-09-2014)“…An overwhelming neutrophil-driven response causes both acute symptoms and the lasting sequelae that result from infection with Neisseria gonorrhoeae…”
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Journal Article -
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Treponema denticola Major Outer Sheath Protein Impairs the Cellular Phosphoinositide Balance That Regulates Neutrophil Chemotaxis. e66209
Published in PloS one (01-06-2013)“…The major outer sheath protein (Msp) of Treponema denticola inhibits neutrophil polarization and directed chemotaxis together with actin dynamics in vitro in…”
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Protective effect of glutamine on intestinal injury and bacterial community in rats exposed to hypobaric hypoxia environment
Published in World journal of gastroenterology : WJG (28-04-2014)“…AIM:To investigate the protective effect of glutamine(Gln)on intestinal injury and the bacterial community in rats exposed to hypobaric hypoxia…”
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A modified single-armed technique for microsurgical vasoepididymostomy
Published in Asian journal of andrology (01-01-2013)“…This study is to evaluate the effectiveness of a modified single-armed suture technique for microsurgical vasoepididymostomy (VE) in patients with epididymal…”
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The effect of the degree of left renal vein constriction on the development of adolescent varicocele in Sprague-Dawley rats
Published in Asian journal of andrology (01-05-2016)“…Experimental models have allowed inquiry into the pathophysiology of varicocele (VC) beyond that possible with human patients. A randomized controlled study in…”
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Journal Article