Search Results - "Sun, Chao‐Yue"
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Phytochemicals: Current strategy to sensitize cancer cells to cisplatin
Published in Biomedicine & pharmacotherapy (01-02-2019)“…Cisplatin-based chemotherapeutic regimens are the most frequently used adjuvant treatments for many types of cancer. However, the development of…”
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Targeting STAT3 inhibition to reverse cisplatin resistance
Published in Biomedicine & pharmacotherapy (01-09-2019)“…[Display omitted] •The intrinsic or acquired resistance to cisplatin remains a major obstacle for cancer therapy.•STAT3 is important for mediating drug…”
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Cascade electrolysis and thermocatalysis: a reliable system for upgrading C1 to C4 hydrocarbons
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Targeting Gut Microbiota With Natural Polysaccharides: Effective Interventions Against High-Fat Diet-Induced Metabolic Diseases
Published in Frontiers in microbiology (15-03-2022)“…Unhealthy diet, in particular high-fat diet (HFD) intake, can cause the development of several metabolic disorders, including obesity, hyperlipidemia, type 2…”
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T helper 17 (Th17) cell responses to the gut microbiota in human diseases
Published in Biomedicine & pharmacotherapy (01-05-2023)“…The gut microbiota colonizing the gastrointestinal tract, is an indispensable “invisible organ” that affects multiple aspects of human health. The gut…”
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Phosphorylation of androgen receptor by mTORC1 promotes liver steatosis and tumorigenesis
Published in Hepatology (Baltimore, Md.) (01-05-2022)“…Background and Aims Androgen receptor (AR) has been reported to play an important role in the development and progression of man’s prostate cancer…”
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Renoprotective effect of scutellarin on cisplatin-induced renal injury in mice: Impact on inflammation, apoptosis, and autophagy
Published in Biomedicine & pharmacotherapy (01-04-2019)“…[Display omitted] •The clinical use of cisplatin is often limited due to its nephrotoxicity.•Scutellarin treatment prevents cisplatin-induced renal injury.•The…”
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Core–shell nanostructure for supra-photothermal CO2 catalysis
Published in Rare metals (01-05-2022)Get full text
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Autophagy and its potent modulators from phytochemicals in cancer treatment
Published in Cancer chemotherapy and pharmacology (01-01-2019)“…Autophagy is a ubiquitous catabolic process by which damaged or harmful intracellular components are delivered to the lysosomes for self-digestion and…”
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Gilteritinib Enhances Anti-Tumor Efficacy of CDK4/6 Inhibitor, Abemaciclib in Lung Cancer Cells
Published in Frontiers in pharmacology (23-06-2022)“…Abemaciclib is a cyclin-dependent kinases 4/6 (CDK4/6) inhibitor approved for the treatment of metastatic breast cancer. Preclinical studies suggest that…”
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Polyoxometalates-derived nanostructures for electrocatalysis application
Published in Rare metals (01-05-2024)“…The conversion of intermittent renewable electrical energy to chemical energy is of great importance, which can not only mitigate current energy and…”
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Scutellarin Increases Cisplatin-Induced Apoptosis and Autophagy to Overcome Cisplatin Resistance in Non-small Cell Lung Cancer via ERK/p53 and c-met/AKT Signaling Pathways
Published in Frontiers in pharmacology (13-02-2018)“…Cisplatin, as the first-line anti-tumor agent, is widely used for treatment of a variety of malignancies including non-small cell lung cancer (NSCLC). However,…”
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Rapamycin and trametinib: a rational combination for treatment of NSCLC
Published in International journal of biological sciences (01-01-2021)“…Mammalian target of rapamycin (mTOR) is one of the most commonly activated pathways in human cancers, including lung cancer. Targeting mTOR with molecule…”
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Combination Treatment With Inhibitors of ERK and Autophagy Enhances Antitumor Activity of Betulinic Acid in Non–small-Cell Lung Cancer In Vivo and In Vitro
Published in Frontiers in pharmacology (29-06-2021)“…Aberrant activation of the Ras–ERK signaling pathway drives many important cancer phenotypes, and several inhibitors targeting such pathways are under…”
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Scutellarin Enhances Antitumor Effects and Attenuates the Toxicity of Bleomycin in H22 Ascites Tumor-Bearing Mice
Published in Frontiers in pharmacology (14-06-2018)“…Bleomycin (BLM) is a broad spectrum anti-tumor drug and inducing pulmonary fibrosis. As an anti-tumor drug without immunosuppression, it is urgent to find a…”
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Supercritical-Carbon Dioxide Fluid Extract from Chrysanthemum indicum Enhances Anti-Tumor Effect and Reduces Toxicity of Bleomycin in Tumor-Bearing Mice
Published in International journal of molecular sciences (24-02-2017)“…Bleomycin (BLM), a family of anti-tumor drugs, was reported to exhibit severe side effects limiting its usage in clinical treatment. Therefore, finding…”
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Polydatin attenuates d-galactose-induced liver and brain damage through its anti-oxidative, anti-inflammatory and anti-apoptotic effects in mice
Published in Food & function (09-11-2016)“…Accumulating evidence has shown that chronic injection of d-galactose (d-gal) can mimic natural aging, with accompanying liver and brain injury. Oxidative…”
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Novel synthesis of 1-substituted-4-imidazolecarboxylates via solvent-free cycloaddition reaction between formamidines and isocyanides
Published in Tetrahedron (29-05-2020)“…A simple and efficient protocol for cyclization between formamidines and ethyl isocyanoacetate has been described in the absence of metal catalyst and solvent…”
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Cholesterol inhibition enhances antitumor response of gilteritinib in lung cancer cells
Published in Cell death & disease (30-09-2024)“…Repositioning approved antitumor drugs for different cancers is a cost-effective approach. Gilteritinib was FDA-approved for the treatment of FLT3-mutated…”
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Pogostone attenuates TNF-α-induced injury in A549 cells via inhibiting NF-κB and activating Nrf2 pathways
Published in International immunopharmacology (01-09-2018)“…Pogostone (PO), a major component of Pogostemon cablin, displays potent protective effects against lipopolysaccharide-induced acute lung injury (ALI) in mice…”
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