Search Results - "Sun, Bryan K"
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Advances in skin grafting and treatment of cutaneous wounds
Published in Science (American Association for the Advancement of Science) (21-11-2014)“…The ability of the skin to repair itself after injury is vital to human survival and is disrupted in a spectrum of disorders. The process of cutaneous wound…”
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Polycomb Proteins Targeted by a Short Repeat RNA to the Mouse X Chromosome
Published in Science (American Association for the Advancement of Science) (31-10-2008)“…To equalize X-chromosome dosages between the sexes, the female mammal inactivates one of her two X chromosomes. X-chromosome inactivation (XCI) is initiated by…”
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A genome-wide long noncoding RNA CRISPRi screen identifies PRANCR as a novel regulator of epidermal homeostasis
Published in Genome research (01-01-2020)“…Genome-wide association studies indicate that many disease susceptibility regions reside in non-protein-coding regions of the genome. Long noncoding RNAs…”
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Intersection of the RNA Interference and X-Inactivation Pathways
Published in Science (American Association for the Advancement of Science) (06-06-2008)“…In mammals, dosage compensation is achieved by X-chromosome inactivation (XCI) in the female. The noncoding Xist gene initiates silencing of the X chromosome,…”
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AhR Regulates Peptidoglycan-Induced Inflammatory Gene Expression in Human Keratinocytes
Published in Journal of innate immunity (2022)“…Bacterial peptidoglycan (PGN) stimulates toll-like receptor 2 (TLR2) on the surface of keratinocytes (KCs), triggering signaling pathways that promote an…”
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Temporal Association of Reduced Serum Vitamin D with COVID-19 Infection: Two Single-Institution Case–Control Studies
Published in Nutrients (02-07-2022)“…(1) Background: Vitamin D supplementation has been proposed for the prevention and treatment of COVID-19, but it is not clear if reduced serum vitamin D…”
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Alternative mRNA splicing events and regulators in epidermal differentiation
Published in Cell reports (Cambridge) (26-03-2024)“…Alternative splicing (AS) of messenger RNAs occurs in ∼95% of multi-exon human genes and generates diverse RNA and protein isoforms. We investigated AS events…”
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A Transient Heterochromatic State in Xist Preempts X Inactivation Choice without RNA Stabilization
Published in Molecular cell (03-03-2006)“…X chromosome inactivation (XCI) depends on a noncoding sense-antisense transcript pair, Xist and Tsix. At the onset of XCI, Xist RNA accumulates on one of two…”
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Mosaic Activating RAS Mutations in Nevus Sebaceus and Nevus Sebaceus Syndrome
Published in Journal of investigative dermatology (01-03-2013)Get full text
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Patient satisfaction in dermatologic care delivered by a medical–student-run free clinic
Published in Journal of the American Academy of Dermatology (01-06-2016)Get full text
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Mutational profile of primary dermal melanoma: A case series
Published in Journal of the American Academy of Dermatology (01-12-2016)Get full text
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Small RNAs in development and disease
Published in Journal of the American Academy of Dermatology (01-11-2008)“…MicroRNAs (miRNAs) and short interfering RNAs (siRNAs) are classes of regulatory small RNA molecules, ranging from 18 to 24 nucleotides in length, whose roles…”
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A pilot study using immunohistochemical staining to characterize dihydropyrimidine dehydrogenase expression in keratinocyte neoplasms
Published in JAAD international (01-06-2023)Get full text
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Non-coding RNAs as skin disease biomarkers, molecular signatures, and therapeutic targets
Published in Human genetics (01-07-2024)“…Non-coding RNAs (ncRNAs) are emerging as biomarkers, molecular signatures, and therapeutic tools and targets for diseases. In this review, we focus…”
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15
The role of enhancers in psoriasis and atopic dermatitis
Published in British journal of dermatology (1951) (20-12-2023)“…Regulatory elements, particularly enhancers, play a crucial role in disease susceptibility and progression. Enhancers are DNA sequences that activate gene…”
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Spectrum of severe ocular complications following dupilumab exposure: A perspective from the ophthalmology clinic
Published in Journal of the American Academy of Dermatology (01-08-2022)Get full text
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The Long Noncoding RNA PRANCR Is Associated with Alternative Splicing of Fibronectin-1 in Keratinocytes
Published in Journal of investigative dermatology (01-09-2023)Get full text
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Differential Methylation of Xite and CTCF Sites in Tsix Mirrors the Pattern of X-Inactivation Choice in Mice
Published in Molecular and Cellular Biology (01-03-2006)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Research Techniques Made Simple: CRISPR Genetic Screens
Published in Journal of investigative dermatology (01-04-2020)“…CRISPR and Cas proteins, often referred to as CRISPR/Cas, are the components of a bacterial genome editing system that can be used to perturb genes in cells…”
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CALML5 is a ZNF750- and TINCR-induced protein that binds stratifin to regulate epidermal differentiation
Published in Genes & development (01-11-2015)“…Outward migration of epidermal progenitors occurs with induction of hundreds of differentiation genes, but the identities of all regulators required for this…”
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