Search Results - "Sun, Bingjun"
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Prodrug-based nanoparticulate drug delivery strategies for cancer therapy
Published in Trends in pharmacological sciences (Regular ed.) (01-11-2014)“…Highlights • Recent trends in prodrug-based nanocarriers for cancer therapy are provided. • Stimuli-sensitive nanoparticulate drug delivery systems (Nano-DDS)…”
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Chemotherapy agent-unsaturated fatty acid prodrugs and prodrug-nanoplatforms for cancer chemotherapy
Published in Journal of controlled release (28-10-2017)“…Unsaturated fatty acids (UFAs), with the distinct advantages of good biocompatibility and innate tumor-targeting effect, have been widely investigated for the…”
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Probing the impact of sulfur/selenium/carbon linkages on prodrug nanoassemblies for cancer therapy
Published in Nature communications (19-07-2019)“…Tumor cells are characterized as redox-heterogeneous intracellular microenvironment due to the simultaneous overproduction of reactive oxygen species and…”
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High Co-loading Capacity and Stimuli-Responsive Release Based on Cascade Reaction of Self-Destructive Polymer for Improved Chemo-Photodynamic Therapy
Published in ACS nano (25-06-2019)“…Photodynamic therapy (PDT) shows a promising synergy with chemotherapy in the therapeutic outcome of malignant cancers. The minimal invasiveness and…”
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Molecularly Self-Engineered Nanoamplifier for Boosting Photodynamic Therapy via Cascade Oxygen Elevation and Lipid ROS Accumulation
Published in ACS applied materials & interfaces (31-08-2022)“…Photodynamic therapy (PDT) has been extensively explored as a noninvasive cancer treatment modality. However, the dilemma of tumor hypoxia and short half-life…”
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Hybrid chalcogen bonds in prodrug nanoassemblies provides dual redox-responsivity in the tumor microenvironment
Published in Nature communications (24-11-2022)“…Sulfur bonds, especially trisulfide bond, have been found to ameliorate the self-assembly stability of homodimeric prodrug nanoassemblies and could trigger the…”
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Influence of anchorage length and pretension on the working resistance of rock bolt based on its tensile characteristics
Published in International journal of coal science & technology (01-12-2021)“…In coal mining roadway support design, the working resistance of the rock bolt is the key factor affecting its maximum support load. Effective improvement of…”
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Synergetic lethal energy depletion initiated by cancer cell membrane camouflaged nano-inhibitor for cancer therapy
Published in Nano research (01-04-2022)“…Mitochondrial bioenergy plays a vital role in the occurrence and development of cancer. Although strategies to impede mitochondrial energy supply have been…”
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Apoptotic body-mediated intercellular delivery for enhanced drug penetration and whole tumor destruction
Published in Science advances (16-04-2021)“…Chemotherapeutic nanomedicines can exploit the neighboring effect to increase tumor penetration. However, the neighboring effect is limited, likely by the…”
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Iterative algorithm for the conformal mapping function from the exterior of a roadway to the interior of a unit circle
Published in Archive of applied mechanics (1991) (2022)“…In elastic mechanics, the complex function method proposed by Muskhelishvili can be used to solve the stress distribution of rock surrounding a roadway with an…”
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Molecularly engineered carrier-free co-delivery nanoassembly for self-sensitized photothermal cancer therapy
Published in Journal of nanobiotechnology (20-09-2021)“…Photothermal therapy (PTT) has been extensively investigated as a tumor-localizing therapeutic modality for neoplastic disorders. However, the hyperthermia…”
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Minor change in the length of carbon chain has a great influence on the antitumor effect of paclitaxel-fatty alcohol prodrug nanoassemblies: Small roles, big impacts
Published in Nano research (01-04-2022)“…Prodrug-based nanoassembly emerges as a hopeful way for the efficient delivery of antitumor drugs, with carrier-free structure and ultra-high drug loading…”
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Elaborately Engineering a Self‐Indicating Dual‐Drug Nanoassembly for Site‐Specific Photothermal‐Potentiated Thrombus Penetration and Thrombolysis
Published in Advanced science (01-02-2022)“…Thrombotic cardio‐cerebrovascular diseases seriously threaten human health. Currently, conventional thrombolytic treatments are challenged by the low…”
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Precisely engineering a dual-drug cooperative nanoassembly for proteasome inhibition-potentiated photodynamic therapy
Published in Chinese chemical letters (01-04-2022)“…Photodynamic therapy (PDT) has been widely investigated for cancer therapy. The intracellular accumulation of reactive oxygen species (ROS)-damaged protein…”
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Small changes in the length of diselenide bond-containing linkages exert great influences on the antitumor activity of docetaxel homodimeric prodrug nanoassemblies
Published in Asian journal of pharmceutical sciences (01-05-2021)“…Homodimeric prodrug-based self-assembled nanoparticles, with carrier-free structure and ultrahigh drug loading, is drawing more and more attentions…”
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Precisely albumin-hitchhiking tumor cell-activated reduction/oxidation-responsive docetaxel prodrugs for the hyperselective treatment of breast cancer
Published in Journal of controlled release (10-09-2018)“…The anticancer efficacy of chemotherapy is greatly limited by short blood circulation and poor tumor selectivity. Thus, anticancer prodrugs with prolonged…”
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Pure photosensitizer-driven nanoassembly with core-matched PEGylation for imaging-guided photodynamic therapy
Published in Acta pharmaceutica Sinica. B (01-11-2021)“…Pure drug-assembled nanomedicines (PDANs) are currently under intensive investigation as promising nanoplatforms for cancer therapy. However, poor colloidal…”
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Iron-doxorubicin prodrug loaded liposome nanogenerator programs multimodal ferroptosis for efficient cancer therapy
Published in Asian journal of pharmceutical sciences (01-11-2021)“…Ferroptosis is a new mode of cell death, which can be induced by Fenton reaction-mediated lipid peroxidation. However, the insufficient H2O2 and high GSH in…”
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Cancer-specific calcium nanoregulator suppressing the generation and circulation of circulating tumor cell clusters for enhanced anti-metastasis combinational chemotherapy
Published in Acta pharmaceutica Sinica. B (01-10-2021)“…Tumor metastasis is responsible for chemotherapeutic failure and cancer-related death. Moreover, circulating tumor cell (CTC) clusters play a pivotal role in…”
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Erythrocyte membrane-camouflaged carrier-free nanoassembly of FRET photosensitizer pairs with high therapeutic efficiency and high security for programmed cancer synergistic phototherapy
Published in Bioactive materials (01-08-2021)“…Phototherapy has been intensively investigated as a non-invasive cancer treatment option. However, its clinical translation is still impeded by unsatisfactory…”
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