Search Results - "Sun, Ben‐hua"

Selective deletion of the receptor for CSF1, c-fms, in osteoclasts results in a high bone mass phenotype, smaller osteoclasts in vivo and an impaired response to an anabolic PTH regimen by Zhu, Meiling, Sun, Ben-Hua, Nevius, Erin, Kaplan, Jared, Pereira, João, Insogna, Karl

“…The receptor for Colony Stimulating Factor 1 (CSF1), c-fms, is highly expressed on mature osteoclasts suggesting a role for this cytokine in regulating the…”
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An Unanticipated Role for Sphingosine Kinase-2 in Bone and in the Anabolic Effect of Parathyroid Hormone by Walker, Joanne M, Yao, Gang-Qing, Siu, Edwin, Zhu, Meiling, Sun, Ben-hua, Simpson, Christine, Insogna, Karl L

“…Sphingosine-1-phosphate (S1P) is an anabolic clastokine. Sphingosine kinase (SPHK) is the rate-limiting enzyme in S1P production and has 2 isoforms. To…”
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Deletion of Rac in Mature Osteoclasts Causes Osteopetrosis, an Age‐Dependent Change in Osteoclast Number, and a Reduced Number of Osteoblasts In Vivo by Zhu, Meiling, Sun, Ben‐hua, Saar, Katarzyna, Simpson, Christine, Troiano, Nancy, Dallas, Sarah L, Tiede‐Lewis, LeAnn M, Nevius, Erin, Pereira, João P, Weinstein, Robert S, Tommasini, Steven M, Insogna, Karl L

“…ABSTRACT Rac1 and Rac2 are thought to have important roles in osteoclasts. Therefore, mice with deletion of both Rac1 and Rac2 in mature osteoclasts (DKO) were…”
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Trends of Yield and Soil Fertility in a Long-Term Wheat-Maize System by YANG, Xue-yun, SUN, Ben-hua, ZHANG, Shu-lan

“…The sustainability of the wheat-maize rotation is important to China＇s food security. Intensive cropping without recycling crop residues or other organic…”
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Measurement of Plasma, Serum, and Platelet Serotonin in Individuals With High Bone Mass and Mutations in LRP5 by Lee, Grace S, Simpson, Christine, Sun, Ben‐Hua, Yao, Chen, Foer, Dinah, Sullivan, Becky, Matthes, Susann, Alenina, Natalia, Belsky, Joseph, Bader, Michael, Insogna, Karl L

“…ABSTRACT It has recently been suggested that the low‐density lipoprotein receptor‐related protein 5 (LRP5) regulates bone mass by suppressing secretion of…”
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AgRP Neurons Regulate Bone Mass by Kim, Jae Geun, Sun, Ben-Hua, Dietrich, Marcelo O., Koch, Marco, Yao, Gang-Qing, Diano, Sabrina, Insogna, Karl, Horvath, Tamas L.

“…The hypothalamus has been implicated in skeletal metabolism. Whether hunger-promoting neurons of the arcuate nucleus impact the bone is not known. We generated…”
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Soil aggregation and aggregate associated organic carbon and total nitrogen under long-term contrasting soil management regimes in loess soil by XIE, Jun-yu, XU, Ming-gang, Ciren, Qiangjiu, YANG, Yang, ZHANG, Shu-lan, SUN, Ben-hua, YANG, Xue-yun

“…This study investigated the effects of three contrasting soil management regimes and different nutrient treatments on the distribution of water-stable…”
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Dominant role of CD47–thrombospondin-1 interactions in myeloma-induced fusion of human dendritic cells: implications for bone disease by Kukreja, Anjli, Radfar, Soroosh, Sun, Ben-Hua, Insogna, Karl, Dhodapkar, Madhav V.

“…Lytic bone disease in myeloma is characterized by an increase in multinucleate osteoclasts in close proximity to tumor cells. However, the nature of osteoclast…”
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Closing the nitrogen use efficiency gap and reducing the environmental impact of wheat-maize cropping on smallholder farms in the Guanzhong Plain, Northwest China by LÜ, Feng-lian, HOU, Miao-miao, ZHANG, Hong-tao, Khan, Asif, Ayaz, Muhammad, QIANGJIU, Ciren, HU, Chang-lu, YANG, Xue-yun, SUN, Ben-hua, ZHANG, Shu-lan

“…A high crop yield with the minimum possible cost to the environment is generally desirable. However, the complicated relationships among crop production,…”
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Increasing dietary protein acutely augments intestinal iron transporter expression and significantly increases iron absorption in rats by Thomas, Carrie E., Gaffney‐Stomberg, Erin, Sun, Ben‐Hua, O'Brien, Kimberly O., Kerstetter, Jane E., Insogna, Karl L.

“…Iron (Fe) deficiency is endemic worldwide. Little data are available regarding acute effects of dietary protein on intestinal Fe absorption. The current study…”
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The Effect of Dietary Protein on Intestinal Calcium Absorption in Rats by Gaffney-Stomberg, Erin, Sun, Ben-hua, Cucchi, Carrie E, Simpson, Christine A, Gundberg, Caren, Kerstetter, Jane E, Insogna, Karl L

“…Increasing dietary protein intake in humans acutely increases urinary calcium. Isotopic absorption studies have indicated that, at least in the short term,…”
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The Anabolic Response to Parathyroid Hormone Is Augmented in Rac2 Knockout Mice by Kawano, Tsutomu, Troiano, Nancy, Adams, Douglas J, Jun Wu, Jian, Sun, Ben-hua, Insogna, Karl

“…PTH is the only currently available anabolic therapy for osteoporosis. In clinical practice, the skeletal response to PTH varies and because therapy is limited…”
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The Effect of Aging on the Skeletal Response to Intermittent Treatment with Parathyroid Hormone by Knopp, Eleanor, Troiano, Nancy, Bouxsein, Mary, Sun, Ben-hua, Lostritto, Karen, Gundberg, Caren, Dziura, James, Insogna, Karl

“…Little is known about the modifying effects of age on the skeletal response to intermittent treatment with PTH. We therefore compared the response of 63 aged…”
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Mitofusin 2 plays a critical role in maintaining the functional integrity of the neuromuscular-skeletal axis by Zhu, Meiling, Zeiss, Caroline, Hamrick, Mark W., Weinstein, Robert S., Sun, Ben-hua, Brotto, Marco, Liu, Xinran, Siu, Edwin, Huttner, Anita, Tommasini, Steven, Simpson, Christine, Insogna, Karl

“…Mitofusin 2 (Mfn2) is one of two mitofusins involved in regulating mitochondrial size, shape and function, including mitophagy, an important cellular mechanism…”
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The contribution of cross-talk between the cell-surface proteins CD36 and CD47–TSP-1 in osteoclast formation and function by Koduru, Srinivas V., Sun, Ben-hua, Walker, Joanne M., Zhu, Meiling, Simpson, Christine, Dhodapkar, Madhav, Insogna, Karl L.

“…Antibody-mediated blockade of cluster of differentiation 47 (CD47)–thrombospondin-1 (TSP-1) interactions blocks osteoclast formation in vitro and attenuates…”
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The Cell Surface Form of Colony-Stimulating Factor-1 Is Biologically Active in Bone in Vivo by Yao, Gang-Qing, Wu, Jain-Jun, Sun, Ben-Hua, Troiano, Nancy, Mitnick, Mary Ann, Insogna, Karl

“…The specific biological function of the cell surface or membrane-bound isoform of colony-stimulating factor-1 (mCSF-1) is not well understood. To help define…”
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Contribution of Atmospheric Nitrogen Compounds to N Deposition in a Broadleaf Forest of Southern China by HU, Zheng-Yi, XU, Cheng-Kai, ZHOU, Li-Na, SUN, Ben-Hua, HE, Yuan-Qiu, ZHOU, Jing, CAO, Zhi-Hong

“…A one-year study in a typical red soil region of southern China was conducted to determine atmospheric nitrogen （N） fluxes of typical N compounds （NH3, NH4-N,…”
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The Transcription Factor T-box 3 Regulates Colony-stimulating Factor 1-dependent Jun Dimerization Protein 2 Expression and Plays an Important Role in Osteoclastogenesis by Yao, Chen, Yao, Gang-Qing, Sun, Ben-hua, Zhang, Changqing, Tommasini, Steven M., Insogna, Karl

“…Colony-stimulating factor 1 (CSF1) is known to promote osteoclast progenitor survival, but its roles in osteoclast differentiation and mature osteoclast…”
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The Cell-surface Form of Colony-stimulating Factor-1 Is Regulated by Osteotropic Agents and Supports Formation of Multinucleated Osteoclast-like Cells by Yao, G Q, Sun, B h, Hammond, E E, Spencer, E N, Horowitz, M C, Insogna, K L, Weir, E C

“…Colony-stimulating factor-1 (CSF-1) is a hematopoietic growth factor that is released by osteoblasts and is recognized to play a critical role in bone…”
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Expression and Synthesis of Bone Morphogenetic Proteins by Osteoclasts: A Possible Path to Anabolic Bone Remodeling by Garimella, Rama, Tague, Sarah E, Zhang, Jianghong, Belibi, Frank, Nahar, Niru, Sun, Ben Hua, Insogna, Karl, Wang, Jinxi, Anderson, H. Clarke

“…Skeletal remodeling is a finely orchestrated process coupling bone formation to bone resorption. The dynamics of coupling is regulated by the microenvironment…”
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