Search Results - "Sumpter, J P"

Several environmental oestrogens are also anti-androgens by Sohoni, P, Sumpter, JP

“…There is presently considerable interest in endocrine disruption which is a new area of endocrinology concerned with chemicals that mimic hormones, in…”
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Identification of Estrogenic Chemicals in STW Effluent. 1. Chemical Fractionation and in Vitro Biological Screening by Desbrow, C, Routledge, E. J, Brighty, G. C, Sumpter, J. P, Waldock, M

“…A fractionation system, combined with an in vitro assay for detecting estrogenic activity, was developed in order to isolate and identify the major estrogenic…”
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Identification of Estrogenic Chemicals in STW Effluent. 2. In Vivo Responses in Trout and Roach by Routledge, E. J, Sheahan, D, Desbrow, C, Brighty, G. C, Waldock, M, Sumpter, J. P

“…The occurrence of certain natural and synthetic steroidal estrogens in the final effluent from STW has been demonstrated. 17β-Estradiol and estrone were…”
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Endocrine Disruption in Wildlife: A Critical Review of the Evidence by Tyler, C. R., Jobling, S., Sumpter, J. P.

“…In recent years, a number of man-made chemicals have been shown to be able to mimic endogenous hormones, and it has been hypothesized that alterations in the…”
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Reproductive Effects of Long-Term Exposure to Bisphenol A in the Fathead Minnow (Pimephales promelas) by Sohoni, P, Tyler, C. R, Hurd, K, Caunter, J, Hetheridge, M, Williams, T, Woods, C, Evans, M, Toy, R, Gargas, M, Sumpter, J. P

“…Bisphenol A (BPA), a high-volume chemical used to make polycarbonate plastic, epoxy resins, and other chemicals has been reported to be weakly estrogenic. To…”
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Altered Sexual Maturation and Gamete Production in Wild Roach (Rutilus rutilus) Living in Rivers That Receive Treated Sewage Effluents by JOBLING, S, BERESFORD, N, NOLAN, M, RODGERS-GRAY, T, BRIGHTY, G. C, SUMPTER, J. P, TYLER, C. R

“…Disruption in gonadal development of wild roach living in U.K. rivers receiving large volumes of treated sewage effluent is manifest in a variety of ways,…”
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Wild Intersex Roach (Rutilus rutilus) Have Reduced Fertility by JOBLING, S, COEY, S, SUMPTER, J. P, WHITMORE, J. G, KIME, D. E, VAN LOOK, K. J. W, MCALLISTER, B. G, BERESFORD, N, HENSHAW, A. C, BRIGHTY, G, TYLER, C. R

“…Endocrine-disrupting chemicals, known to be present in the environment, have great potential for interfering with reproductive health in wildlife and humans…”
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Rapid loss of estrogenicity of steroid estrogens by UVA photolysis and photocatalysis over an immobilised titanium dioxide catalyst by Coleman, H.M., Routledge, E.J., Sumpter, J.P., Eggins, B.R., Byrne, J.A.

“…The presence of low levels of natural and synthetic steroid estrogens in the aquatic environment, and their biological effects on aquatic organisms, are…”
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Steroid hormones in the aquatic environment by Ojoghoro, J.O., Scrimshaw, M.D., Sumpter, J.P.

“…Steroid hormones are extremely important natural hormones in all vertebrates. They control a wide range of physiological processes, including osmoregulation,…”
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Development of a Reproductive Performance Test for Endocrine Disrupting Chemicals Using Pair-Breeding Fathead Minnows (Pimephales promelas) by Harries, J. E, Runnalls, T, Hill, E, Harris, C. A, Maddix, S, Sumpter, J. P, Tyler, C. R

“…Existing in vivo tests (with the exception of the full life-cycle test) are not adequate for assessing the reproductive effects of endocrine disrupting…”
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Widespread Sexual Disruption in Wild Fish by Jobling, Susan, Nolan, Monique, Tyler, Charles R, Brighty, Geoff, Sumpter, John P

“…A number of chemicals present in the environment have been shown to mimic or antagonize the actions of steroid hormones, an issue often described as “endocrine…”
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Effects of the synthetic estrogen 17α-ethinylestradiol on the life-cycle of the fathead minnow (Pimephales promelas) by Länge, Reinhard, Hutchinson, Thomas H., Croudace, Charlotte P., Siegmund, Fred, Schweinfurth, Hermann, Hampe, Peter, Panter, Grace H., Sumpter, John P.

“…A fish full life‐cycle (FFLC) study was conducted for 17α‐ethinylestradiol (EE2) using the fathead minnow, Pimephales promelas. Newly fertilized embryos (<24 h…”
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Adverse reproductive effects in male fathead minnows ( Pimephales promelas) exposed to environmentally relevant concentrations of the natural oestrogens, oestradiol and oestrone by Panter, G.H, Thompson, R.S, Sumpter, J.P

“…Recent research has shown that low concentrations of natural and synthetic oestrogens are present in sewage treatment works effluents. However, the effects of…”
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Vitellogenesis as a biomarker for estrogenic contamination of the aquatic environment by Sumpter, J P, Jobling, S

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Out-of-season production of 17,20β-dihydroxypregn-4-en-3-one in the roach Rutilus rutilus by Scott, A. P., Hill, T., Beresford, N., Runnalls, T. J., Sumpter, J. P., Ellis, T.

“…In this study, although the highest production of two physiologically significant progestins in teleosts [17,20β‐dihydroxypregn‐4‐en‐3‐one (17,20β‐P) and…”
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Estrogenic activity of surfactants and some of their degradation products assessed using a recombinant yeast screen by Routledge, Edwin J., Sumpter, John P.

“…An estrogen‐inducible screen was developed in yeast (Saccharomyces cerevisiae) in order to assess whether surfactants and their major degradation products are…”
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Oocyte growth and development in teleosts by Tyler, C. R., Sumpter, J. P.

“…Oocyte growth and development is an important issue in fish and fisheries biology. This paper reviews the information available on oocyte growth patterns and…”
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The apparently very variable potency of the anti-depressant fluoxetine by Sumpter, J.P., Donnachie, R.L., Johnson, A.C.

“…•Different aquatic species appear to have very different sensitivities to fluoxetine.•Some species of invertebrate appear to be extremely sensitive to…”
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Gestational and Lactational Exposure of Rats to Xenoestrogens Results in Reduced Testicular Size and Sperm Production by Sharpe, Richard M., Fisher, Janes S., Millar, Mike M., Jobling, Susan, Sumpter, John P.

“…This study assessed whether exposure of male rats to two estrogenic, environmental chemicals, 4-octylphenol (OP) and butyl benzyl phthalate (BBP) during…”
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Exposure of Juvenile Roach (Rutilus rutilus) to Treated Sewage Effluent Induces Dose-Dependent and Persistent Disruption in Gonadal Duct Development by Rodgers-Gray, Trevor P, Jobling, Susan, Kelly, Carole, Morris, Steven, Brighty, Geoff, Waldock, Michael J, Sumpter, John P, Tyler, Charles R

“…Wild roach (Rutilus rutilus) have been found with intersex gonads in rivers throughout the United Kingdom. The incidence of intersexuality is strongly…”
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