Search Results - "Sumner, Whitney"
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Role of B Cells in Responses to Checkpoint Blockade Immunotherapy and Overall Survival of Cancer Patients
Published in Clinical cancer research (15-11-2021)“…The role of B cells in the tumor microenvironment and B-cell-mediated antitumor immune responses remains relatively understudied. Recent seminal studies have…”
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2
Keeping Kids Kool—Influence of Induction, Advantage of Adaptation, Curtailment of Complications
Published in International journal of radiation oncology, biology, physics (01-09-2021)Get full text
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3
Depressed pacemaker activity of sinoatrial node myocytes contributes to the age-dependent decline in maximum heart rate
Published in Proceedings of the National Academy of Sciences - PNAS (29-10-2013)“…An inexorable decline in maximum heart rate (mHR) progressively limits human aerobic capacity with advancing age. This decrease in mHR results from an…”
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4
Evaluating predictive factors for toxicities experienced by head & neck cancer patients undergoing radiotherapy
Published in Journal of translational medicine (07-09-2021)“…Purpose The purpose of this study was to evaluate if HPV status serves as an independent predictor of early and late dysphagia outcomes when considered…”
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5
Quality improvement intervention to reduce time to postoperative radiation in head and neck free flap patients
Published in Head & neck (01-11-2021)“…Background Best‐practice guidelines for head and neck cancer patients advise postoperative radiation therapy (PORT) initiation within 6 weeks of surgery. We…”
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Gene alterations as predictors of radiation-induced toxicity in head and neck squamous cell carcinoma
Published in Journal of translational medicine (17-05-2021)“…Optimizing the therapeutic ratio for radiation therapy (RT) in head and neck squamous cell carcinoma (HNSCC) is uniquely challenging owing to high rates of…”
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Survival impact of pre-treatment neutrophils on oropharyngeal and laryngeal cancer patients undergoing definitive radiotherapy
Published in Journal of translational medicine (02-08-2017)“…Squamous cell carcinoma of the head and neck (HNSCC) represents an array of disease processes with a generally unfavorable prognosis. Inflammation plays an…”
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Radiation Recall Pneumonitis After Treatment With Checkpoint Blockade Immunotherapy: A Case Series and Review of Literature
Published in Frontiers in oncology (30-04-2021)“…Radiation recall pneumonitis (RRP) is a poorly understood clinical syndrome in which patients develop radiation pneumonitis triggered by a systemic agent,…”
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Defining the Role of Immunotherapy in the Curative Treatment of Locoregionally Advanced Head and Neck Cancer: Promises, Challenges, and Opportunities
Published in Frontiers in oncology (21-09-2021)“…Recent advancements in the development of immunotherapies have raised the hope for patients with locally-advanced HNSCC (LA-HNSCC) to achieve improved…”
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10
Adaptive replanning using cone beam CT for deformation of original CT simulation
Published in Journal of medical radiation sciences (01-06-2022)“…Background During a course of radiation therapy, anatomical changes such as a decrease in tumour size or weight loss can trigger the need for repeating a…”
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11
The Bcl-2 Homology-3 Domain (BH3)-Only Proteins, Bid, DP5/Hrk, and BNip3L, Are Upregulated in Reactive Astrocytes of End-Stage Mutant SOD1 Mouse Spinal Cord
Published in Frontiers in cellular neuroscience (30-01-2018)“…The molecular mechanisms leading to motor neuron death in amyotrophic lateral sclerosis (ALS) are unknown; however, several studies have provided evidence of a…”
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End of treatment cone-beam computed tomography (CBCT) is predictive of radiation response and overall survival in oropharyngeal squamous cell carcinoma
Published in Radiation oncology (London, England) (09-08-2021)“…Image guidance in radiation oncology has resulted in significant improvements in the accuracy and precision of radiation therapy (RT). Recently, the resolution…”
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A Cystine-Rich Whey Supplement (Immunocal®) Provides Neuroprotection from Diverse Oxidative Stress-Inducing Agents In Vitro by Preserving Cellular Glutathione
Published in Oxidative medicine and cellular longevity (01-01-2017)“…Oxidative stress is a principal mechanism underlying the pathophysiology of neurodegeneration. Therefore, nutritional enhancement of endogenous antioxidant…”
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A comparison of concurrent cisplatin versus cetuximab with radiotherapy in locally-advanced head and neck cancer: A bi-institutional analysis
Published in Reports of practical oncology and radiotherapy (01-09-2017)“…To present our experience comparing cisplatin- and cetuximab-based radiotherapy for locally-advanced head and neck squamous cell carcinoma. The comparative…”
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Survival benefit of postoperative radiation in papillary meningioma: Analysis of the National Cancer Data Base
Published in Reports of practical oncology and radiotherapy (01-11-2017)“…Papillary meningioma represents a rare subset of World Health Organization (WHO) Grade III meningioma that portends an overall poor prognosis. There is…”
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A Cystine-Rich Whey Supplement (Immunocal(®)) Delays Disease Onset and Prevents Spinal Cord Glutathione Depletion in the hSOD1(G93A) Mouse Model of Amyotrophic Lateral Sclerosis
Published in Antioxidants (12-12-2014)“…Depletion of the endogenous antioxidant, glutathione (GSH), underlies progression of the devastating neurodegenerative disease, amyotrophic lateral sclerosis…”
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A Cystine-Rich Whey Supplement (Immunocal®) Delays Disease Onset and Prevents Spinal Cord Glutathione Depletion in the hSOD1G93A Mouse Model of Amyotrophic Lateral Sclerosis
Published in Antioxidants (12-12-2014)“…Depletion of the endogenous antioxidant, glutathione (GSH), underlies progression of the devastating neurodegenerative disease, amyotrophic lateral sclerosis…”
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18
Association Between Lymph Node Ratio and Recurrence and Survival Outcomes in Patients With Oral Cavity Cancer
Published in JAMA otolaryngology-- head & neck surgery (01-01-2019)“…Oral cavity squamous cell carcinoma (OCSCC) is associated with often-delayed clinical diagnosis, poor prognosis, and expensive therapeutic approaches…”
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Activated B Cells and Plasma Cells Are Resistant to Radiation Therapy
Published in International journal of radiation oncology, biology, physics (01-02-2022)“…B cells play a key role in outcomes of cancer patients and responses to checkpoint blockade immunotherapies. However, the effect of radiation therapy on B cell…”
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Racial, Ethnic, and Socioeconomic Discrepancies in Opioid Prescriptions Among Older Patients With Cancer
Published in JCO oncology practice (01-06-2021)“…Minority race and lower socioeconomic status are associated with lower rates of opioid prescription and undertreatment of pain in multiple noncancer healthcare…”
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