Search Results - "Sumner, Susan J"

One Step Forward for Reducing False Positive and False Negative Compound Identifications from Mass Spectrometry Metabolomics Data: New Algorithms for Constructing Extracted Ion Chromatograms and Detecting Chromatographic Peaks by Myers, Owen D, Sumner, Susan J, Li, Shuzhao, Barnes, Stephen, Du, Xiuxia

“…False positive and false negative peaks detected from extracted ion chromatograms (EIC) are an urgent problem with existing software packages that preprocess…”
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Detailed Investigation and Comparison of the XCMS and MZmine 2 Chromatogram Construction and Chromatographic Peak Detection Methods for Preprocessing Mass Spectrometry Metabolomics Data by Myers, Owen D, Sumner, Susan J, Li, Shuzhao, Barnes, Stephen, Du, Xiuxia

“…XCMS and MZmine 2 are two widely used software packages for preprocessing untargeted LC/MS metabolomics data. Both construct extracted ion chromatograms (EICs)…”
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A Review of Metabolic Targets of Anticancer Nutrients and Nutraceuticals in Pre-Clinical Models of Triple-Negative Breast Cancer by Wiggs, Alleigh, Molina, Sabrina, Sumner, Susan J, Rushing, Blake R

“…Triple-negative breast cancer (TNBC) is a subtype of breast cancer that is notoriously aggressive and has poorer outcomes as compared with other breast cancer…”
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Potential serum biomarkers from a metabolomics study of autism by Wang, Han, PhD, Liang, Shuang, PhD, Gao, Jingquan, PhD, Sun, Caihong, PhD, Wang, Jia, PhD, Xia, Wei, MD, Wu, Shiying, PhD, Wang, Maoqing, PhD, Sun, Changhao, PhD, Wu, Lijie, PhD, Sumner, Susan J., PhD, Zhang, Fengyu, PhD

“…Background Early detection and diagnosis are very important for autism. Current diagnosis of autism relies mainly on some observational questionnaires and…”
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Analysis of Human Serum and Whole Blood for Mineral Content by ICP-MS and ICP-OES: Development of a Mineralomics Method by Harrington, James M, Young, Daniel J, Essader, Amal S, Sumner, Susan J, Levine, Keith E

“…Minerals are inorganic compounds that are essential to the support of a variety of biological functions. Understanding the range and variability of the content…”
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Maternal Serum Metabolomics in Mid-Pregnancy Identifies Lipid Pathways as a Key Link to Offspring Obesity in Early Childhood by Francis, Ellen C, Kechris, Katerina, Johnson, Randi K, Rawal, Shristi, Pathmasiri, Wimal, Rushing, Blake R, Du, Xiuxia, Jansson, Thomas, Dabelea, Dana, Sumner, Susan J, Perng, Wei

“…Maternal metabolism during pregnancy shapes offspring health via in utero programming. In the Healthy Start study, we identified five subgroups of pregnant…”
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The Effects of Diet and Exercise on Endogenous Estrogens and Subsequent Breast Cancer Risk in Postmenopausal Women by Wiggs, Alleigh G, Chandler, Justin K, Aktas, Aynur, Sumner, Susan J, Stewart, Delisha A

“…Endogenous estrogens have been associated with overall breast cancer risk, particularly for postmenopausal women, and ways to reduce these estrogens have…”
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Untargeted metabolomics reveal signatures of a healthy lifestyle by Pathmasiri, Wimal, Rushing, Blake R., McRitchie, Susan, Choudhari, Mansi, Du, Xiuxia, Smirnov, Alexsandr, Pelleigrini, Matteo, Thompson, Michael J., Sakaguchi, Camila A., Nieman, David C., Sumner, Susan J.

“…This cross-sectional study investigated differences in the plasma metabolome in two groups of adults that were of similar age but varied markedly in body…”
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Associations between the gut microbiome and metabolome in early life by Nguyen, Quang P, Karagas, Margaret R, Madan, Juliette C, Dade, Erika, Palys, Thomas J, Morrison, Hilary G, Pathmasiri, Wimal W, McRitche, Susan, Sumner, Susan J, Frost, H Robert, Hoen, Anne G

“…The infant intestinal microbiome plays an important role in metabolism and immune development with impacts on lifelong health. The linkage between the…”
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Multi-omics analysis of glucose-mediated signaling by a moonlighting Gβ protein Asc1/RACK1 by Li, Shuang, Li, Yuanyuan, Rushing, Blake R., Harris, Sarah E., McRitchie, Susan L., Jones, Janice C., Dominguez, Daniel, Sumner, Susan J., Dohlman, Henrik G.

“…Heterotrimeric G proteins were originally discovered through efforts to understand the effects of hormones, such as glucagon and epinephrine, on glucose…”
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Oral administration of TiO2 nanoparticles during early life impacts cardiac and neurobehavioral performance and metabolite profile in an age- and sex-related manner by Mortensen, Ninell P, Pathmasiri, Wimal, Snyder, Rodney W, Caffaro, Maria Moreno, Watson, Scott L, Patel, Purvi R, Beeravalli, Lakshmi, Prattipati, Sharmista, Aravamudhan, Shyam, Sumner, Susan J, Fennell, Timothy R

“…Abstract Background Nanoparticles (NPs) are increasingly incorporated in everyday products. To investigate the effects of early life exposure to orally…”
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Maternal Early Pregnancy Serum Metabolomics Profile and Abnormal Vaginal Bleeding as Predictors of Placental Abruption: A Prospective Study by Gelaye, Bizu, Sumner, Susan J, McRitchie, Susan, Carlson, James E, Ananth, Cande V, Enquobahrie, Daniel A, Qiu, Chunfang, Sorensen, Tanya K, Williams, Michelle A

“…Placental abruption, an ischemic placental disorder, complicates about 1 in 100 pregnancies, and is an important cause of maternal and perinatal morbidity and…”
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Early life exposure to vitamin D deficiency impairs molecular mechanisms that regulate liver cholesterol biosynthesis, energy metabolism, inflammation, and detoxification by Knuth, Megan M, Xue, Jing, Elnagheeb, Marwa, Gharaibeh, Raad Z, Schoenrock, Sarah A, McRitchie, Susan, Brouwer, Cory, Sumner, Susan J, Tarantino, Lisa, Valdar, William, Rector, R Scott, Simon, Jeremy M, Ideraabdullah, Folami

“…Emerging data suggests liver disease may be initiated during development when there is high genome plasticity and the molecular pathways supporting liver…”
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A Metabolomics Approach to Investigate Kukoamine B-A Potent Natural Product With Anti-diabetic Properties by Li, Yuan-Yuan, Stewart, Delisha A, Ye, Xiao-Min, Yin, Li-Hua, Pathmasiri, Wimal W, McRitchie, Susan L, Fennell, Timothy R, Cheung, Hon-Yeung, Sumner, Susan J

“…Due to the surge in type 2 diabetes mellitus (T2DM), treatments for chronic metabolic dysregulations with fewer side-effects are sought. Lycii Cortex (LyC), a…”
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Multi-Omics Analysis of Multiple Glucose-Sensing Receptor Systems in Yeast by Li, Shuang, Li, Yuanyuan, Rushing, Blake R, Harris, Sarah E, McRitchie, Susan L, Dominguez, Daniel, Sumner, Susan J, Dohlman, Henrik G

“…The yeast has long been used to produce alcohol from glucose and other sugars. While much is known about glucose metabolism, relatively little is known about…”
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Metabolomics reveals biomarkers of opioid use disorder by Ghanbari, Reza, Li, Yuanyuan, Pathmasiri, Wimal, McRitchie, Susan, Etemadi, Arash, Pollock, Jonathan D., Poustchi, Hossein, Rahimi-Movaghar, Afarin, Amin-Esmaeili, Masoumeh, Roshandel, Gholamreza, Shayanrad, Amaneh, Abaei, Behrouz, Malekzadeh, Reza, Sumner, Susan C. J.

“…Opioid use disorder (OUD) is diagnosed using the qualitative criteria defined by the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition…”
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Sex-Specific Metabolic Effects of Dietary Folate Withdrawal in Wild-Type and Aldh1l1 Knockout Mice by Sharma, Jaspreet, Rushing, Blake R, Hall, Madeline S, Helke, Kristi L, McRitchie, Susan L, Krupenko, Natalia I, Sumner, Susan J, Krupenko, Sergey A

“…ALDH1L1 (10-formyltetrahydrofolate dehydrogenase), an enzyme of folate metabolism, is highly expressed in the liver. It regulates the overall flux of…”
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Correlated metabolomic, genomic, and histologic phenotypes in histologically normal breast tissue by Sun, Xuezheng, Stewart, Delisha A, Sandhu, Rupninder, Kirk, Erin L, Pathmasiri, Wimal W, McRitchie, Susan L, Clark, Robert F, Troester, Melissa A, Sumner, Susan J

“…Breast carcinogenesis is a multistep process accompanied by widespread molecular and genomic alterations, both in tumor and in surrounding microenvironment. It…”
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Macronutrient-differential dietary pattern impacts on body weight, hepatic inflammation, and metabolism by Li, Yuan-Yuan, Madduri, Supradeep S, Rezeli, Erika T, Santos, Charlene, Freeman Iii, Herman, Peng, Jing, McRitchie, Susan L, Pathmasiri, Wimal, Hursting, Stephen D, Sumner, Susan J, Stewart, Delisha A

“…Obesity is a multi-factorial disease frequently associated with poor nutritional habits and linked to many detrimental health outcomes. Individuals with…”
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Predicting and Defining Steroid Resistance in Pediatric Nephrotic Syndrome Using Plasma Metabolomics by Gooding, Jessica R., Agrawal, Shipra, McRitchie, Susan, Acuff, Zach, Merchant, Michael L., Klein, Jon B., Smoyer, William E., Sumner, Susan J., Mahan, John, Patel, Hiren, Ransom, Richard F., Pan, Cynthia, Geary, Denis F., Chang, Myra L., Gibson, Keisha L., Iorember, Franca M., Brophy, Patrick D., Srivastava, Tarak, Greenbaum, Larry A.

“…Nephrotic syndrome (NS) is a kidney disease that affects both children and adults. Glucocorticoids have been the primary therapy for >60 years but are…”
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