Search Results - "Sumner, Susan"
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Blood type biochemistry and human disease
Published in Wiley interdisciplinary reviews. Systems biology and medicine (01-11-2016)“…Associations between blood type and disease have been studied since the early 1900s when researchers determined that antibodies and antigens are inherited. In…”
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One Step Forward for Reducing False Positive and False Negative Compound Identifications from Mass Spectrometry Metabolomics Data: New Algorithms for Constructing Extracted Ion Chromatograms and Detecting Chromatographic Peaks
Published in Analytical chemistry (Washington) (05-09-2017)“…False positive and false negative peaks detected from extracted ion chromatograms (EIC) are an urgent problem with existing software packages that preprocess…”
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Detailed Investigation and Comparison of the XCMS and MZmine 2 Chromatogram Construction and Chromatographic Peak Detection Methods for Preprocessing Mass Spectrometry Metabolomics Data
Published in Analytical chemistry (Washington) (05-09-2017)“…XCMS and MZmine 2 are two widely used software packages for preprocessing untargeted LC/MS metabolomics data. Both construct extracted ion chromatograms (EICs)…”
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Obesity Increases Mortality and Modulates the Lung Metabolome during Pandemic H1N1 Influenza Virus Infection in Mice
Published in The Journal of immunology (1950) (15-05-2015)“…Obese individuals are at greater risk for hospitalization and death from infection with the 2009 pandemic H1N1 influenza virus (pH1N1). In this study,…”
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Direct and transgenerational effects of low doses of perinatal di-(2-ethylhexyl) phthalate (DEHP) on social behaviors in mice
Published in PloS one (01-02-2017)“…Di-(2-ethylhexyl) phthalate (DEHP) is an endocrine disrupting chemical commonly used as a plasticizer in medical equipment, food packaging, flooring, and…”
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Metabolomics Workbench: An international repository for metabolomics data and metadata, metabolite standards, protocols, tutorials and training, and analysis tools
Published in Nucleic acids research (04-01-2016)“…The Metabolomics Workbench, available at www.metabolomicsworkbench.org, is a public repository for metabolomics metadata and experimental data spanning various…”
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Patterns of infant fecal metabolite concentrations and social behavioral development in toddlers
Published in Pediatric research (01-07-2024)“…Background Gut-derived metabolites, products of microbial and host co-metabolism, may inform mechanisms underlying children’s neurodevelopment. We investigated…”
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Existing antiviral options against SARS-CoV-2 replication in COVID-19 patients
Published in Future microbiology (01-12-2020)“…COVID-19 caused by SARS-CoV-2, is an international concern. This infection requires urgent efforts to develop new antiviral compounds. To date, no specific…”
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Metabolites as biomarkers of adverse reactions following vaccination: A pilot study using nuclear magnetic resonance metabolomics
Published in Vaccine (01-03-2017)“…Highlights • Metabolomics is the study of the small-molecule metabolite profile of an organism. • Metabolomics may help identify individuals predisposed to…”
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Human microbiota, blood group antigens, and disease
Published in Wiley interdisciplinary reviews. Systems biology and medicine (01-05-2018)“…Far from being just “bugs in our guts,” the microbiota interacts with the body in previously unimagined ways. Research into the genome and the microbiome has…”
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Potential serum biomarkers from a metabolomics study of autism
Published in Journal of psychiatry & neuroscience (2016)“…Background Early detection and diagnosis are very important for autism. Current diagnosis of autism relies mainly on some observational questionnaires and…”
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A Review of Metabolic Targets of Anticancer Nutrients and Nutraceuticals in Pre-Clinical Models of Triple-Negative Breast Cancer
Published in Nutrients (10-05-2022)“…Triple-negative breast cancer (TNBC) is a subtype of breast cancer that is notoriously aggressive and has poorer outcomes as compared with other breast cancer…”
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Transforming Big Data into AI‐ready data for nutrition and obesity research
Published in Obesity (Silver Spring, Md.) (01-05-2024)“…Objective Big Data are increasingly used in obesity and nutrition research to gain new insights and derive personalized guidance; however, this data in raw…”
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Multi-omics analysis of glucose-mediated signaling by a moonlighting Gβ protein Asc1/RACK1
Published in PLoS genetics (01-07-2021)“…Heterotrimeric G proteins were originally discovered through efforts to understand the effects of hormones, such as glucagon and epinephrine, on glucose…”
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Metabolomics enables precision medicine: “A White Paper, Community Perspective”
Published in Metabolomics (2016)“…Introduction: Background to metabolomics Metabolomics is the comprehensive study of the metabolome, the repertoire of biochemicals (or small molecules) present…”
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Comparison of Lysis and Detachment Sample Preparation Methods for Cultured Triple-Negative Breast Cancer Cells Using UHPLC-HRMS-Based Metabolomics
Published in Metabolites (10-02-2022)“…Dysregulation of cellular metabolism is now a well-recognized hallmark of cancer. Studies investigating the metabolic features of cancer cells have shed new…”
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The role of gut microbial community and metabolomic shifts in adaptive resistance of Atlantic killifish (Fundulus heteroclitus) to polycyclic aromatic hydrocarbons
Published in The Science of the total environment (01-07-2021)“…Altered gut microbiomes may play a role in rapid evolution to anthropogenic change but remain poorly understood. Atlantic killifish (Fundulus heteroclitus) in…”
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Metabolomics reveals biomarkers of opioid use disorder
Published in Translational psychiatry (04-02-2021)“…Opioid use disorder (OUD) is diagnosed using the qualitative criteria defined by the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition…”
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Disposition of intravenously or orally administered silver nanoparticles in pregnant rats and the effect on the biochemical profile in urine
Published in Journal of applied toxicology (01-05-2017)“…Few investigations have been conducted on the disposition and fate of silver nanoparticles (AgNP) in pregnancy. The distribution of a single dose of…”
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Commensal microbiota is hepatoprotective and prevents liver fibrosis in mice
Published in The FASEB journal (01-03-2015)“…Translocation of bacteria and their products across the intestinal barrier is common in patients with liver disease, and there is evidence that experimental…”
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