Search Results - "Summers deLuca, Leslie"

Fine-tuning of dendritic cell biology by the TNF superfamily by deLuca, Leslie Summers, Gommerman, Jennifer L.

“…Key Points TNF superfamily members have diverse functions in mammalian biology and are often expressed by cells of the immune system. TNF superfamily members…”
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LTβR signaling in dendritic cells induces a type I IFN response that is required for optimal clonal expansion of CD8⁺ T cells by Summers deLuca, Leslie, Ng, Dennis, Gao, Yunfei, Wortzman, Michael E, Watts, Tania H, Gommerman, Jennifer L

“…During an immune response, antigen-bearing dendritic cells (DCs) migrate to the local draining lymph node and present antigen to CD4⁺ helper T cells…”
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A TNF-α-CCL20-CCR6 axis regulates Nod1-induced B cell responses by Paradis, Maude, Mindt, Barbara C, Duerr, Claudia U, Rojas, Olga L, Ng, Dennis, Boulianne, Bryant, McCarthy, Doug D, Yu, Mingxi Dennis, Summers deLuca, Leslie E, Ward, Lesley A, Waldron, James B, Philpott, Dana J, Gommerman, Jennifer L, Fritz, Jörg H

“…Innate immune responses provoke the accumulation of leukocytes at sites of inflammation. In addition to monocytes and granulocytes, B cells also participate in…”
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Exploring the psychosocial needs of persons with lower extremity amputation and feasibility of internet cognitive behavioural therapy: a qualitative study by Mayo, Amanda L., Fung, Vera, Hitzig, Sander L., Gould, Sarah, Posa, Stephanie, Summers deLuca, Leslie, Kayssi, Ahmed

“…Following major lower extremity amputation (LEA), patients experience significant emotional distress and are at risk for anxiety and depression. There is a…”
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Qualitative research in vascular surgery by Ma, Gar-Way, Botros, Daniel, Summers deLuca, Leslie, Kayssi, Ahmed

“…Qualitative research aims to understand and describe subjective experiences and perceptions. Qualitative and mixed-methods research, in which quantitative and…”
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Evaluation of the Efficacy of an Online Learning Module to Increase Wound Care Theoretical Knowledge Amongst Medical Students by Ma, Gar-Way, Summers deLuca, Leslie, Bernatchez, Julien, Ojeda, Cesar Cuen, Chauhan, Anjali, Botros, Daniel, Selim, Omar, Kayssi, Ahmed

“…•Online learning modules are effective at teaching students wound care basics.•Students find online learning modules acceptable.•Embedded photos in learning…”
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Substrain Differences Reveal Novel Disease-Modifying Gene Candidates That Alter the Clinical Course of a Rodent Model of Multiple Sclerosis by deLuca, Leslie E. Summers, Pikor, Natalia B, O'Leary, Jennifer, Galicia-Rosas, Georgina, Ward, Lesley A, Defreitas, Dustin, Finlay, Trisha M, Ousman, Shalina S, Osborne, Lucy R, Gommerman, Jennifer L

“…Experimental autoimmune encephalomyelitis (EAE) is a rodent model of multiple sclerosis that is executed in animals by immunization with myelin Ag in adjuvant…”
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LTβR and CD40: working together in dendritic cells to optimize immune responses by Gommerman, Jennifer L., Summers deLuca, Leslie

“…Generating an immune response tailored to destroy an infecting organism while limiting bystander damage involves guiding T‐cell activation using a variety of…”
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A sphingosine-1-phosphate receptor 1-directed agonist reduces central nervous system inflammation in a plasmacytoid dendritic cell-dependent manner by Galicia-Rosas, Georgina, Pikor, Natalia, Schwartz, Jordan A, Rojas, Olga, Jian, Allen, Summers-Deluca, Leslie, Ostrowski, Mario, Nuesslein-Hildesheim, Barbara, Gommerman, Jennifer L

“…Gradients of the sphingolipid sphingosine-1-phosphate (S1P) are responsible for the egress of lymphocytes from lymph nodes by activating the S1P1 receptor…”
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The lymphotoxin pathway as a novel regulator of dendritic cell function by Summers Deluca, Leslie, Gommerman, Jennifer L

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BAFF induces a hyper-IgA syndrome in the intestinal lamina propria concomitant with IgA deposition in the kidney independent of LIGHT by McCarthy, Douglas D., Chiu, Sidney, Gao, Yunfei, Summers-deLuca, Leslie E., Gommerman, Jennifer L.

“…BAFF is a peripheral B cell survival factor and can mediate antibody (Ab) class switching. Over-expression of BAFF in mice results in B cell hyperplasia,…”
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The lymphotoxin pathway: beyond lymph node development by McCarthy, Douglas D, Summers-Deluca, Leslie, Vu, Frances, Chiu, Sidney, Gao, Yunfei, Gommerman, Jennifer L

“…The first studies of mice deficient in lymphotoxin-alpha (LTalpha), LTbeta and LTbetaR revealed the seminal discovery that the LTbetaR signaling is critical…”
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Machine Learning Classification of Doppler Waveforms by Van Asseldonk, Brandon, Summers deLuca, Leslie, Kayssi, Ahmed

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Global Bibliometric Analysis of Vascular Surgery Research Output (2000-2023) by Javidan, Arshia P., Baqri, Wafa, Akouris, Polycronis, Balta, Kaan, Summers deLuca, Leslie, Kayssi, Ahmed

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Integration of Th17- and Lymphotoxin-Derived Signals Initiates Meningeal-Resident Stromal Cell Remodeling to Propagate Neuroinflammation by Pikor, Natalia B., Astarita, Jillian L., Summers-Deluca, Leslie, Galicia, Georgina, Qu, Joy, Ward, Lesley A., Armstrong, Susan, Dominguez, Claudia X., Malhotra, Deepali, Heiden, Brendan, Kay, Robert, Castanov, Valera, Touil, Hanane, Boon, Louis, O’Connor, Paul, Bar-Or, Amit, Prat, Alexandre, Ramaglia, Valeria, Ludwin, Samuel, Turley, Shannon J., Gommerman, Jennifer L.

“…Tertiary lymphoid tissues (TLTs) have been observed in the meninges of multiple sclerosis (MS) patients, but the stromal cells and molecular signals that…”
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Nuclear factor-κB1 controls the functional maturation of dendritic cells and prevents the activation of autoreactive T cells by Dissanayake, Dilan, Hall, Håkan, Berg-Brown, Nancy, Elford, Alisha R, Hamilton, Sara R, Murakami, Kiichi, Deluca, Leslie Summers, Gommerman, Jennifer L, Ohashi, Pamela S

“…Although maturation of dendritic cells can drive autoimmune responses in mice, it remains unclear whether intrinsic factors hold dendritic cells in a resting…”
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LTβR and CD40: working together in dendritic cells to optimize immune responses: TNF Receptor Family Members by GOMMERMAN, Jennifer L, SUMMERS DELUCA, Leslie

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Expression of lymphotoxin-αβ on antigen-specific T cells is required for DC function by Summers-deLuca, Leslie E., McCarthy, Douglas D., Cosovic, Bojana, Ward, Lesley A., Lo, Calvin C., Scheu, Stefanie, Pfeffer, Klaus, Gommerman, Jennifer L.

“…During an immune response, activated antigen (Ag)-specific T cells condition dendritic cells (DCs) to enhance DC function and survival within the inflamed…”
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LTβR signaling in Dendritic Cells induces a Type I IFN response that is required for optimal clonal expansion of CD8+ T cells (100.40) by Ng, Dennis, Summers deLuca, Leslie, Gao, Yunfei, Wortzman, Michael, Watts, Tania, Gommerman, Jennifer

“…Abstract During an acute infection, dendritic cells (DC) are triggered by pattern recognition receptors (PRR) to produce inflammatory molecules that are…”
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LT[Beta]R signaling in dendritic cells induces a type I IFN response that is required for optimal clonal expansion of CD8+ T cells by deLuca, Leslie Summers, Ng, Dennis, Gao, Yunfei, Wortzman, Michael E, Watts, Tania H, Gommerman, Jennifer L

“…During an immune response, antigen-bearing dendritic cells (DCs) migrate to the local draining lymph node and present antigen to CD4+ helper T cells…”
Get full text