Search Results - "Summers, Elizabeth J"

Pembrolizumab in brain metastases of diverse histologies: phase 2 trial results by Brastianos, Priscilla K., Kim, Albert E., Giobbie-Hurder, Anita, Lee, Eudocia Q., Lin, Nancy U., Overmoyer, Beth, Wen, Patrick Y., Nayak, Lakshmi, Cohen, Justine V., Dietrich, Jorg, Eichler, April, Heist, Rebecca S., Krop, Ian, Lawrence, Donald, Ligibel, Jennifer, Tolaney, Sara, Mayer, Erica, Winer, Eric, Bent, Brittany, de Sauvage, Magali A., Ijad, Nazanin, Larson, Juliana M., Marion, Braxton, Nason, Sally, Murthy, Naina, Ratcliff, Sherry, Summers, Elizabeth J., Mahar, Maura, Shih, Helen A., Oh, Kevin, Cahill, Daniel P., Gerstner, Elizabeth R., Sullivan, Ryan J.

“…Brain metastases (BMs) are an emerging challenge in oncology due to increasing incidence and limited treatments. Here, we present results of a single-arm,…”
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The ERK inhibitor LY3214996 augments anti-PD-1 immunotherapy in preclinical mouse models of BRAFV600E melanoma brain metastasis by de Sauvage, Magali A, Torrini, Consuelo, Nieblas-Bedolla, Edwin, Summers, Elizabeth J, Sullivan, Emily, Zhang, Britney S, Batchelor, Emily, Marion, Braxton, Yamazawa, Erika, Markson, Samuel C, Wakimoto, Hiroaki, Nayyar, Naema, Brastianos, Priscilla K

“…Immune checkpoint inhibitors (ICI) have revolutionized cancer treatment; however, only a subset of patients with brain metastasis (BM) respond to ICI…”
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Abnormal vascular structure and function within brain metastases is linked to pembrolizumab resistance by Kim, Albert E, Lou, Kevin W, Giobbie-Hurder, Anita, Chang, Ken, Gidwani, Mishka, Hoebel, Katharina, Patel, Jay B, Cleveland, Mason C, Singh, Praveer, Bridge, Christopher P, Ahmed, Syed Rakin, Bearce, Benjamin A, Liu, William, Fuster-Garcia, Elies, Lee, Eudocia Q, Lin, Nancy U, Overmoyer, Beth, Wen, Patrick Y, Nayak, Lakshmi, Cohen, Justine V, Dietrich, Jorg, Eichler, April, Heist, Rebecca, Krop, Ian, Lawrence, Donald, Ligibel, Jennifer, Tolaney, Sara, Mayer, Erica, Winer, Eric, Perrino, Carmen M, Summers, Elizabeth J, Mahar, Maura, Oh, Kevin, Shih, Helen A, Cahill, Daniel P, Rosen, Bruce R, Yen, Yi-Fen, Kalpathy-Cramer, Jayashree, Martinez-Lage, Maria, Sullivan, Ryan J, Brastianos, Priscilla K, Emblem, Kyrre E, Gerstner, Elizabeth R

“…Abstract Background We recently conducted a phase 2 trial (NCT028865685) evaluating intracranial efficacy of pembrolizumab for brain metastases (BM) of diverse…”
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EXTH-41. COMBINATION TREATMENT WITH RAF/MEK AND FAK INHIBITION ENHANCES TUMOR GROWTH INHIBITION IN MENINGIOMA by Ijad, Nazanin, Waller, Katie L, Yamazawa, Erika, Nayyar, Naema, Summers, Elizabeth J, Migliarese, Christian, Galanis, Evanthia, Carlson, Brett L, Sarkaria, Jann N, Wakimoto, Hiroaki, Vaubel, Rachael A, Brastianos, Priscilla K

“…Abstract BACKGROUND Patients with meningiomas who have progressed after multimodal treatments face a significant shortage of viable therapeutic options. Recent…”
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