Search Results - "Sumioka, Takayoshi"

Loss of sphingosine 1-phosphate receptor 3 gene function impairs injury-induced stromal angiogenesis in mouse cornea by Yasuda, Shingo, Sumioka, Takayoshi, Iwanishi, Hiroki, Okada, Yuka, Miyajima, Masayasu, Ichikawa, Kana, Reinach, Peter S., Saika, Shizuya

“…Sphingosine 1-phosphate (S1P) is a bioactive sphingolipid generated through sphingosine kinase1 (SPK1)-mediated phosphorylation of sphingosine. We show here…”
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Roles of Epithelial and Mesenchymal TRP Channels in Mediating Inflammatory Fibrosis by Okada, Yuka, Sumioka, Takayoshi, Reinach, Peter S, Miyajima, Masayasu, Saika, Shizuya

“…The maintenance of normal vision is dependent on preserving corneal transparency. For this to occur, this tissue must remain avascular and its stromal…”
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Impairment of corneal epithelial wound healing is association with increased neutrophil infiltration and reactive oxygen species activation in tenascin X-deficient mice by Sumioka, Takayoshi, Iwanishi, Hiroki, Okada, Yuka, Miyajima, Masayasu, Ichikawa, Kana, Reinach, Peter S., Matsumoto, Ken-ichi, Saika, Shizuya

“…The purpose of the study was to uncover the role of tenascin X in modulation of healing in mouse corneas subjected to epithelium debridement. Healing in…”
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Loss of TRPV4 Cation Channel Inhibition of Macrophage Infiltration and Neovascularization in a Mouse Cornea by Sumioka, Takayoshi, Iwanishi, Hiroki, Yasuda, Shingo, Ichikawa, Kana, Miyazima, Masayasu, Kokado, Masahide, Okada, Yuka, Saika, Shizuya

“…Corneal injury–associated inflammation could induce inward-growing neovascularization from the periphery of the tissue. Such neovascularization could cause…”
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Loss of TRPV4 Function Suppresses Inflammatory Fibrosis Induced by Alkali-Burning Mouse Corneas by Okada, Yuka, Shirai, Kumi, Miyajima, Masayasu, Reinach, Peter S, Yamanaka, Osamu, Sumioka, Takayoshi, Kokado, Masahide, Tomoyose, Katsuo, Saika, Shizuya

“…In humans suffering from pulmonary disease and a mouse model, transient receptor potential vanilloid 4 (TRPV4) channel activation contributes to fibrosis. As a…”
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A Glaucoma Patient with an Intraocular Pressure Decrease following Total Gastrectomy and Postoperative Anticancer Treatment by Takada, Yukihisa, Sumioka, Takayoshi, Tamura, Tadahiko, Saika, Shizuya

“…We herein report a case of glaucoma with an intraocular pressure (IOP) decrease following total gastrectomy (TG) and anticancer treatment for gastric cancer. A…”
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Sensory nerve supports epithelial stem cell function in healing of corneal epithelium in mice: the role of trigeminal nerve transient receptor potential vanilloid 4 by Okada, Yuka, Sumioka, Takayoshi, Ichikawa, Kana, Sano, Hiromi, Nambu, Atsushi, Kobayashi, Kenta, Uchida, Kunitoshi, Suzuki, Yoshiro, Tominaga, Makoto, Reinach, Peter Sol, Hirai, Syu-ichi, Jester, James V., Miyajima, Masayasu, Shirai, Kumi, Iwanishi, Hiroki, Kao, Winston Whei-Yang, Liu, Chia-Yang, Saika, Shizuya

“…In order to understand the pathobiology of neurotrophic keratopathy, we established a mouse model by coagulating the first branch of the trigeminal nerve (V1…”
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Impairment of corneal epithelial wound healing in a TRPV1-deficient mouse by Sumioka, Takayoshi, Okada, Yuka, Reinach, Peter S, Shirai, Kumi, Miyajima, Masayasu, Yamanaka, Osamu, Saika, Shizuya

“…To examine whether the absence or blockage of an ion channel receptor, transient receptor potential vanilloid subtype 1 (TRPV1), affects the healing of an…”
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Loss of tenascin X gene function impairs injury‐induced stromal angiogenesis in mouse corneas by Sumioka, Takayoshi, Iwanishi, Hiroki, Okada, Yuka, Nidegawa, Yuka, Miyajima, Masayasu, Matsumoto, Ken‐ichi, Saika, Shizuya

“…To determine the contribution by tenascin X (Tnx) gene expression to corneal stromal angiogenesis, the effects were determined of its loss on this response in…”
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Impaired healing of cornea incision injury in a TRPV1-deficient mouse by Nidegawa-Saitoh, Yuka, Sumioka, Takayoshi, Okada, Yuka, Reinach, Peter S., Flanders, Kathleen C., Liu, Chia-Yang, Yamanaka, Osamu, Kao, Winston Whei-Yang, Saika, Shizuya

“…The present study attempts to elucidate the role of TRPV1 cation channel receptor on primary repair in an incision-wounded mouse cornea in vivo. Previous study…”
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Transient Receptor Potential Channels and Corneal Stromal Inflammation by Okada, Yuka, Reinach, Peter S, Shirai, Kumi, Kitano-Izutani, Ai, Miyajima, Masayasu, Yamanaka, Osamu, Sumioka, Takayoshi, Saika, Shizuya

“…Corneal transparency is dependent on the maintenance of the structural integrity and functional activity of its epithelial and endothelial limiting layers and…”
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Anomaly of cornea and ocular adnexa in spinster homolog 2 (Spns2) knockout mice by Yasuda, Shingo, Sumioka, Takayoshi, Miyajima, Masayasu, Iwanishi, Hiroki, Morii, Tomoya, Mochizuki, Naoki, Reinach, Peter S., Kao, Winston W.Y., Okada, Yuka, Liu, Chia-Yang, Saika, Shizuya

“…Spinster 2 (Spns2) is a transporter that pumps sphingosine-1-phosphate (S1P), a bioactive lipid mediator synthesized in the cytoplasm, out of cells into the…”
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The Role of Extracellular Matrix in Corneal Wound Healing by Yamanaka, Osamu, Sumioka, Takayoshi, Saika, Shizuya

“…During wound healing, cell migration, proliferation, differentiation, and enhanced biosynthetic activities are observed at the sites of injury. Interactions…”
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Long-term intraocular pressure after switching a combination ophthalmic medication of β-blocker/prostaglandin by Takada, Yukihisa, Sumioka, Takayoshi, Nakagawa, Masaki, Saika, Shizuya

“…PURPOSE: We examined intraocular pressure (IOP)-reducing effects 12 months after switching timolol maleate/travoprost combination ophthalmic solution in one…”
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Therapeutic Penetrating Keratoplasty in a Case of Corneal Perforation Caused by Colletotrichum gloeosporioides Infection by Imai, Kazuki, Sumioka, Takayoshi, Iwanishi, Hiroki, Takada, Yukihisa, Murata, Shin'ichi, Iwamoto, Ryuta, Okada, Yuka, Saika, Shizuya

“…: Corneal infection of is uncommon and usually limited to the anterior stroma. However, we observed a case of corneal stromal perforation caused by this fungus…”
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Impaired cornea wound healing in a tenascin C-deficient mouse model by Sumioka, Takayoshi, Kitano, Ai, Flanders, Kathleen C, Okada, Yuka, Yamanaka, Osamu, Fujita, Norihito, Iwanishi, Hiroki, Kao, Winston W-Y, Saika, Shizuya

“…We investigated the effects of loss of tenascin C on the healing of the stroma using incision-injured mice corneas. Tenascin C was upregulated in the stroma…”
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Effects of a prostaglandin F2alpha derivative glaucoma drug on EGF expression and E-cadherin expression in a corneal epithelial cell line by Takada, Yukihisa, Yamanaka, Osamu, Okada, Yuka, Sumioka, Takayoshi, Reinach, Peter S., Saika, Shizuya

“…Purpose: We examined the effects of travoprost on cell proliferation-related signals and E-cadherin expression in vitro and in situ in order to obtain evidence…”
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A Case of Repeating Transient Increase in Intraocular Pressure by Instability of an Intraocular Lens Implanted in the Capsular Bag by Takada, Yukihisa , Sumioka, Takayoshi, Ishikawa, Nobuyuki, Yasuda, Shingo, Komori, Ryoko, Saika, Shizuya

“…We observed repeated episodes of rapid increases in intraocular pressure (IOP) considered to be caused by an in-the-bag intraocular lens (IOL) instability in a…”
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Temperature-sensitive transient receptor potential channels in corneal tissue layers and cells by Mergler, Stefan, Valtink, Monika, Takayoshi, Sumioka, Okada, Yuka, Miyajima, Masayasu, Saika, Shizuya, Reinach, Peter S

“…We here provide a brief summary of the characteristics of transient receptor potential channels (TRPs) identified in corneal tissue layers and cells. In…”
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Histological Analysis of a Cornea Following Experimental Femtosecond Laser Ablation by Sumioka, Takayoshi, Miyamoto, Takeshi, Takatsuki, Reiko, Okada, Yuka, Yamanaka, Osamu, Saika, Shizuya

“…Corneal photorefractive surgery is currently performed by ablation of corneal stroma under the stromal flap. A stromal flap is created using a femtosecond (FS)…”
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