Dissemination of MCR-Type Genes Encoding Polymyxin Resistance in Russia and Across the Globe

Dissemination of MCR-Type Genes Encoding Polymyxin Resistance in Russia and Across the Globe

The MCR-type polymyxin resistance gene localized on a mobile genetic element was described was described in 2015 for the first time. Publications, following the first description, demonstrated the global distribution of MCR-type genes and the role of animal husbandry in this process. At the same tim...

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Bibliographic Details
Published in:Antibiotiki i himioterapiâ Vol. 66; no. 1-2; pp. 57 - 64
Main Authors: Ageevets, V. A., Sulyan, О. S., Lazareva, I. V., Sukhinin, A. A.
Format: Journal Article
Language:English
Russian
Published: LLC "Publishing House OKI" 06-05-2021
Subjects:
distribution
mcr-type genes
origin
polymyxins
Online Access:Get full text
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Description
Summary:The MCR-type polymyxin resistance gene localized on a mobile genetic element was described was described in 2015 for the first time. Publications, following the first description, demonstrated the global distribution of MCR-type genes and the role of animal husbandry in this process. At the same time, practical importance of polymyxins is growing, considering spread of genes of acquired resistance to carbapenem antibiotics. This review briefly summarizes the principal data on this issue. 
ISSN:0235-2990
DOI:10.37489/0235-2990-2021-66-1-2-57-64